Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

Prevention and Control of Influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

Fiore, A. E., Shay, D. K., Broder, K. R., Iskander, J. K., Uyeki, T. M., Mootrey, G., Bresee, J. S., & Cox, N. S. (2001) · PsycEXTRA Dataset · doi:10.1037/e548312006-001 · Cited by 5,006

Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

Thompson, W. W., Shay, D. K., Weintraub, E., Brammer, L., Cox, N., Anderson, L. J., & Fukuda, K. (2003) · JAMA · doi:10.1001/jama.289.2.179 · Cited by 3,673

Influenza-Associated Hospitalizations in the United States

Thompson, W. W. (2004) · JAMA · doi:10.1001/jama.292.11.1333 · Cited by 2,213

Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010.

Fiore, A. E., Uyeki, T. M., Broder, K. R., Finelli, L., Euler, G. L., Singleton, J. A., Iskander, J. K., Wortley, P. M., Shay, D. K., Bresee, J., et al. (2009) · PubMed · Cited by 1,964

Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis

Osterholm, M. T., Kelley, N. S., Sommer, A., & Belongia, E. A. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70295-x · Cited by 1,789

The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature

Gross, P. A., Hermogenes, A. W., Sacks, H. S., Lau, J., & Levandowski, R. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-7-199510010-00008 · Cited by 1,100

The Efficacy of Influenza Vaccination in Elderly Individuals

Govaert, T. M. E. (1994) · JAMA · doi:10.1001/jama.1994.03520210045030 · Cited by 883

Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population

Simonsen, L., Reichert, T. A., Viboud, C. G., Blackwelder, W. C., Taylor, R. J., & Miller, M. A. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.3.265 · Cited by 541

Randomized, Double‐Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High‐Dose and Standard‐Dose Influenza Vaccine in Adults 65 Years of Age and Older

Falsey, A. R., Treanor, J. J., Tornieporth, N., Capellan, J., & Gorse, G. J. (2009) · The Journal of Infectious Diseases · doi:10.1086/599790 · Cited by 388

Influenza Activity — United States, 2015–16 Season and Composition of the 2016–17 Influenza Vaccine

Davlin, S. L., Blanton, L., Kniss, K. L., Mustaquim, D., Smith, S., Kramer, N. A., Cohen, J., Cummings, C. N., Garg, S., Flannery, B. L., et al. (2016) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6522a3 · Cited by 328

The humoral immune response to high-dose influenza vaccine in persons with monoclonal B-cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL)

Whitaker, J. A., Parikh, S. A., Shanafelt, T. D., Kay, N. E., Kennedy, R. B., Grill, D. E., Goergen, K. M., Call, T. G., Kendarian, S. S., Ding, W., et al. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.01.001 · Cited by 38

Erratum: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

Zuo, T., Sun, J., Wang, G., Jiang, L., Zuo, Y., Li, D., Shi, X., Liu, X., Fan, S., Ren, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms10757 · Cited by 38

Burden of influenza in the elderly: a narrative review

Conrad, A., Valour, F., & Vanhems, P. (2023) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000931 · Cited by 37

The relative vaccine effectiveness of high-dose vs standard-dose influenza vaccines in preventing hospitalization and mortality: A meta-analysis of evidence from randomized trials

Skaarup, K. G., Lassen, M. C. H., Modin, D., Johansen, N. D., Loiacono, M. M., Harris, R. C., Lee, J. K. H., Dufournet, M., Vardeny, O., Peikert, A., et al. (2024) · Journal of Infection · doi:10.1016/j.jinf.2024.106187 · Cited by 37

Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults

Leroux-Roels, I., Huang, G., Ferguson, M., Kohli, A., Clark, R., Bickel, M., Soens, M., Du, E., Pucci, A., Hicks, B., et al. (2026) · New England Journal of Medicine · doi:10.1056/nejmoa2516491 · Cited by 37

Effect of Previous-Year Vaccination on the Efficacy, Immunogenicity, and Safety of High-Dose Inactivated Influenza Vaccine in Older Adults

DiazGranados, C. A., Dunning, A. J., Robertson, C. A., Talbot, H. K., Landolfi, V. A., & Greenberg, D. P. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw085 · Cited by 37

Vaccination of Adults in General Medical Practice

Hunter, P. H., Fryhofer, S. A., & Szilagyi, P. G. (2020) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2019.02.024 · Cited by 39

Randomized comparison of the safety of Flublok® versus licensed inactivated influenza vaccine in healthy, medically stable adults ≥50 years of age

Izikson, R., Leffell, D. J., Bock, S. A., PATRIARCA, P. A., Post, P. L., Dunkle, L. M., & Cox, M. M. J. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.10.097 · Cited by 36

Vaccinology in the third millennium: scientific and social challenges

Poland, G. A., Whitaker, J. A., Poland, C. M., Ovsyannikova, I. G., & Kennedy, R. B. (2016) · Current Opinion in Virology · doi:10.1016/j.coviro.2016.03.003 · Cited by 36

Public health and economic benefits of seasonal influenza vaccination in risk groups in France, Italy, Spain and the UK: state of play and perspectives

de Fougerolles, T. R., Baïssas, T., Perquier, G., Vitoux, O., Crépey, P., Bartelt-Hofer, J., Bricout, H., & Petitjean, A. (2024) · BMC Public Health · doi:10.1186/s12889-024-18694-5 · Cited by 35

Mismatching between circulating strains and vaccine strains of influenza: Effect on Hajj pilgrims from both hemispheres

Alfelali, M., Khandaker, G., Booy, R., & Rashid, H. (2015) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1085144 · Cited by 35

Immunogenicity and safety of high-dose versus standard-dose inactivated influenza vaccine in rheumatoid arthritis patients: a randomised, double-blind, active-comparator trial

Colmegna, I., Useche, M., Rodríguez, K. M. G., McCormack, D., Alfonso, G., Patel, A., Ramanakumar, A. V., Rahme, E., Bernatsky, S., Hudson, M., et al. (2019) · The Lancet Rheumatology · doi:10.1016/s2665-9913(19)30094-3 · Cited by 35

Influenza vaccine: progress in a vaccine that elicits a broad immune response

Isakova–Sivak, I., Stepanova, E., Mezhenskaya, D. А., Matyushenko, V., Prokopenko, P., Sychev, I. А., Wong, P.-F., & Георгиевна, Р. Л. (2021) · Expert Review of Vaccines · doi:10.1080/14760584.2021.1964961 · Cited by 35

Influenza Viruses: Innate Immunity and mRNA Vaccines

Lee, S., & Ryu, J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.710647 · Cited by 36

Aging, the Medical Subspecialties, and Career Development: Where We Were, Where We Are Going

Hurria, A., High, K. P., Mody, L., Horne, F. M., Escobedo, M. R., Halter, J. B., Hazzard, W. R., Schmader, K. E., Klepin, H. D., Lee, S., et al. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14708 · Cited by 34

Relative and Absolute Effectiveness of High-Dose and Standard-Dose Influenza Vaccine Against Influenza-Related Hospitalization Among Older Adults—United States, 2015–2017

Doyle, J., Beacham, L. A., Martin, E. T., Talbot, H. K., Monto, A. S., Gaglani, M., Middleton, D. B., Silveira, F. P., Zimmerman, R. K., Alyanak, E., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa160 · Cited by 34

Influenza Vaccination for the Prevention of Cardiovascular Disease in the Americas: Consensus document of the Inter-American Society of Cardiology and the Word Heart Federation

Liprandi, Á. S., Liprandi, M. I. S., Zaidel, E. J., Aisenberg, G. M., Baranchuk, A. M., Barbosa, E. C. D., Sánchez, G. B., Alexander, B., Lanas, F. T., López-Santi, R., et al. (2021) · Global Heart · doi:10.5334/gh.1069 · Cited by 34

Sex-specific effects of aging on humoral immune responses to repeated influenza vaccination in older adults

Shapiro, J. R., Li, H., Morgan, R., Chen, Y., Kuo, H., Ning, X., Shea, P., Wu, C., Merport, K., Saldanha, R., et al. (2021) · npj Vaccines · doi:10.1038/s41541-021-00412-6 · Cited by 34

Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses

Falloon, J., Talbot, H. K., Curtis, C. T., Ervin, J. E., Krieger, D., Dubovsky, F., Takas, T., Yu, J., Li, Y., Lambert, S. L., et al. (2017) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00157-17 · Cited by 34

Analysis of relative effectiveness of high-dose versus standard-dose influenza vaccines using an instrumental variable method

Young‐Xu, Y., Snider, J. T., van Aalst, R., Mahmud, S. M., Thommes, E. W., Lee, J. K. H., Greenberg, D. P., & Chit, A. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.01.063 · Cited by 34

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN)

Cheng, A. C., Holmes, M., Dwyer, D. E., Senenayake, S., Cooley, L., Irving, L. B., Simpson, G., Korman, T. M., Macartney, K. K., Friedman, N. D., et al. (2019) · Communicable Diseases Intelligence · doi:10.33321/cdi.2019.43.48 · Cited by 34

Infection in Kidney Transplantation

Nambiar, P. H., Silibovsky, R., & Belden, K. A. (2018) · Springer eBooks · doi:10.1007/978-3-319-19617-6_22 · Cited by 33

Influenza vaccine strategies for solid organ transplant recipients

Hirzel, C., & Kumar, D. (2018) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000461 · Cited by 33

Effectiveness of Influenza Vaccine for Preventing Laboratory-Confirmed Influenza Hospitalizations in Immunocompromised Adults

Hughes, K., Middleton, D. B., Nowalk, M. P., Balasubramani, G. K., Martin, E. T., Gaglani, M., Talbot, H. K., Patel, M. M., Ferdinands, J. M., Zimmerman, R. K., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa1927 · Cited by 33

Humoral and cellular immune responses to recombinant herpes zoster vaccine in patients with chronic lymphocytic leukemia and monoclonal B cell lymphocytosis

Muchtar, E., Koehler, A. B., Johnson, M. J., Rabe, K. G., Ding, W., Call, T. G., Leis, J. F., Kenderian, S. S., Hayman, S. R., Wang, Y., et al. (2021) · American Journal of Hematology · doi:10.1002/ajh.26388 · Cited by 33

High-Dose Seasonal Influenza Vaccine in Patients Undergoing Dialysis

Miskulin, D. C., Weiner, D. E., Tighiouart, H., Lacson, E. K., Jr., Meyer, K. B., Dad, T., & Manley, H. J. (2018) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03390318 · Cited by 33

Targeting the hallmarks of aging to improve influenza vaccine responses in older adults

Cadar, A. N., Martin, D. E., & Bartley, J. M. (2023) · Immunity & Ageing · doi:10.1186/s12979-023-00348-6 · Cited by 34

High-affinity anti-glycan antibodies: challenges and strategies

Polonskaya, Z., Savage, P. B., Finn, M. G., & Teyton, L. (2019) · Current Opinion in Immunology · doi:10.1016/j.coi.2019.03.004 · Cited by 32

Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination

Loeb, N., Andrew, M. K., Loeb, M. B., Kuchel, G. A., Haynes, L., McElhaney, J. E., & Verschoor, C. P. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa148 · Cited by 32

Advances in the prevention, management, and treatment of community-acquired pneumonia

Pletz, M. W., Rohde, G. G. U., Welte, T., Kolditz, M., & Ott, S. R. (2016) · F1000Research · doi:10.12688/f1000research.7657.1 · Cited by 32

Improved immunogenicity of high-dose influenza vaccine compared to standard-dose influenza vaccine in adult oncology patients younger than 65 years receiving chemotherapy: A pilot randomized clinical trial

Jamshed, S., Walsh, E. E., Dimitroff, L. J., Santelli, J. S., & Falsey, A. R. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.12.037 · Cited by 31

The effect of disease-modifying antirheumatic drugs on vaccine immunogenicity in adults

Day, A. L., Winthrop, K. L., & Curtis, J. R. (2020) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.87a.20056 · Cited by 32

The Interplay between Immunosenescence and Microbiota in the Efficacy of Vaccines

Cianci, R., Franza, L., Massaro, M. G., Borriello, R., Vito, F., & Gambassi, G. (2020) · Vaccines · doi:10.3390/vaccines8040636 · Cited by 32

Factors influencing the immunogenicity of influenza vaccines

Wen, S., Wu, Z., Zhong, S., Mao, L., & Shu, Y. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.1875761 · Cited by 34

Animal Models Utilized for the Development of Influenza Virus Vaccines

Roubidoux, E. K., & Schultz‐Cherry, S. (2021) · Vaccines · doi:10.3390/vaccines9070787 · Cited by 31

Immunogenicity of High-Dose Versus MF59-Adjuvanted Versus Standard Influenza Vaccine in Solid Organ Transplant Recipients: The Swiss/Spanish Trial in Solid Organ Transplantation on Prevention of Influenza (STOP-FLU Trial)

Mombelli, M., Neofytos, D., Huynh‐Do, U., Sánchez‐Céspedes, J., Stampf, S., Golshayan, D., Dahdal, S., Stirnimann, G., Schnyder, A., Garzoni, C., et al. (2023) · Clinical Infectious Diseases · doi:10.1093/cid/ciad477 · Cited by 30

Antibody-mediated NK cell activation as a correlate of immunity against influenza infection

Boudreau, C. M., Burke, J. S., Yousif, A. S., Sangesland, M., Jastrzebski, S. L., Verschoor, C. P., Kuchel, G. A., Lingwood, D., Kleanthous, H., Bruijn, I. D., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-40699-8 · Cited by 30

Effectiveness of Influenza Vaccination Among Older Adults Across Kidney Function: Pooled Analysis of 2005-2006 Through 2014-2015 Influenza Seasons

Ishigami, J., Sang, Y., Grams, M. E., Coresh, J., Chang, A. R., & Matsushita, K. (2019) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2019.09.008 · Cited by 30

Innate Immune Responses of Vaccinees Determine Early Neutralizing Antibody Production After ChAdOx1nCoV-19 Vaccination

Shen, C., Yen, C., Fu, Y.-C., Cheng, C., Shen, T.-C., Chang, P.-D., Cheng, K., Liu, H., Chang, Y., Chen, P., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.807454 · Cited by 30

Seasonal Influenza Vaccine Effectiveness in Persons Aged 15–64 Years: A Systematic Review and Meta-Analysis

Martins, J. P., Santos, M., Martins, A. M., Felgueiras, M. M., & Santos, R. (2023) · Vaccines · doi:10.3390/vaccines11081322 · Cited by 31

Comparison of AS03 and Alum on immune responses elicited by A/H3N2 split influenza vaccine in young, mature and aged BALB/c mice

Yam, K. K., Gupta, J., Allen, E. K., Burt, K. R., Beaulieu, É., Mallett, C. P., Burt, D. S., & Ward, B. J. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.02.012 · Cited by 30

Influenza Vaccines: Current Status, Adjuvant Strategies, and Efficacy

Mokalla, V. R., Gundarapu, S., Kaushik, R. S., Rajput, M., & Tummala, H. (2025) · Vaccines · doi:10.3390/vaccines13090962 · Cited by 29

Seasonal influenza immunisation: Strategies for older adults

Schaffner, W., Buynder, P. G. V., McNeil, S., & Osterhaus, A. D. M. E. (2018) · International Journal of Clinical Practice · doi:10.1111/ijcp.13249 · Cited by 30

Comparative Reactogenicity of Enhanced Influenza Vaccines in Older Adults

Cowling, B. J., Thompson, M. G., Ng, T. W. Y., Fang, V. J., Perera, R. A. P. M., Leung, N., Chen, Y., So, H. C., Ip, D., & Iuliano, A. D. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa255 · Cited by 29

Clinical practice guidelines 2019: Indian consensus-based recommendations on influenza vaccination in adults

Dhar, R., Ghoshal, A. G., Guleria, R., Sharma, S., Kulkarni, T., Swarnakar, R., Samaria, J., Chaudhary, S., Gaur, S., Christopher, D., et al. (2020) · Lung India · doi:10.4103/lungindia.lungindia_270_20 · Cited by 29

Recombinant hemagglutinin influenza vaccine provides broader spectrum protection

Dunkle, L. M., & Izikson, R. (2016) · Expert Review of Vaccines · doi:10.1080/14760584.2016.1203261 · Cited by 29

Surveillance for Guillain-Barré syndrome after 2015–2016 and 2016–2017 influenza vaccination of Medicare beneficiaries

Arya, D., Said, M. A., Izurieta, H. S., Pérez-Vilar, S., Zinderman, C. E., Wernecke, M., Alexander, M., White, T., Su, I., Lufkin, B., et al. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.08.045 · Cited by 29

A retrospective cohort study assessing relative effectiveness of adjuvanted versus high-dose trivalent influenza vaccines among older adults in the United States during the 2018–19 influenza season

Pelton, S. I., Divino, V. M., Postma, M. J., Shah, D., Mould-Quevedo, J. F., DeKoven, M., & Krishnarajah, G. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.03.054 · Cited by 29

SARS-CoV-2-specific humoral and cell-mediated immune responses after immunization with inactivated COVID-19 vaccine in kidney transplant recipients (CVIM 1 study)

Bruminhent, J., Setthaudom, C., Chaumdee, P., Boongird, S., Kiertiburanakul, S., Malathum, K., Nongnuch, A., Phuphuakrat, A., Jirasiritham, S., Janphram, C., et al. (2021) · American Journal of Transplantation · doi:10.1111/ajt.16867 · Cited by 28

Vaccines for healthcare-associated infections: present, future, and expectations

Gagneux‐Brunon, A., Lucht, F., Launay, O., Berthelot, P., & Botelho-Nevers, É. (2018) · Expert Review of Vaccines · doi:10.1080/14760584.2018.1470507 · Cited by 28

Assessing the effectiveness of high-dose influenza vaccine in preventing hospitalization among seniors, and observations on the limitations of effectiveness study design

Robison, S. G., & Thomas, A. R. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.09.050 · Cited by 28

Considering Frailty in SARS-CoV-2 Vaccine Development: How Geriatricians Can Assist

Andrew, M. K., Schmader, K. E., Rockwood, K. J., Clarke, B., & McElhaney, J. E. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s295522 · Cited by 28

Effect of Age on Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccines Among US Medicare Beneficiaries Aged ≥65 Years

Lu, Y., Chillarige, Y., Izurieta, H. S., Wei, Y., Xu, W., Lu, M., Sung, H.-M., Lindaas, A., Wernecke, M., MaCurdy, T. E., et al. (2019) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiz360 · Cited by 28

The baculovirus expression vector system: a modern technology for the future of influenza vaccine manufacturing

Trombetta, C. M., Marchi, S., & Montomoli, E. (2022) · Expert Review of Vaccines · doi:10.1080/14760584.2022.2085565 · Cited by 28

Influenza vaccination strategy in acute coronary syndromes: the VIP-ACS trial

Fonseca, H. A. R., Furtado, R. H. M., Zimerman, A., Lemos, P. A., Franken, M., Monfardini, F., Pedrosa, R. P., Patriota, R. D. L. S., Passos, L. C. S., Dall’Orto, F. T. C., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac472 · Cited by 28

Cost-effectiveness of influenza vaccination with a high dose quadrivalent vaccine of the elderly population in Belgium, Finland, and Portugal

Alvarez, F. P., Chevalier, P., Borms, M., Bricout, H., Marques, C., Soininen, A., Sainio, T., Petit, C., & de Courville, C. (2023) · Journal of Medical Economics · doi:10.1080/13696998.2023.2194193 · Cited by 28

Public Health Impact of the Adjuvanted RSVPreF3 Vaccine for Respiratory Syncytial Virus Prevention Among Older Adults in the United States

Molnar, D., La, E. M., Verelst, F., Poston, S. A., Graham, J., Bellinghen, L.-A. V., & Curran, D. (2024) · Infectious Diseases and Therapy · doi:10.1007/s40121-024-00939-w · Cited by 28

Safety, Reactogenicity, and Health-Related Quality of Life After Trivalent Adjuvanted vs Trivalent High-Dose Inactivated Influenza Vaccines in Older Adults

Schmader, K. E., Liu, C., Harrington, T. A., Rountree, W., Auerbach, H., Walter, E. B., Barnett, E. D., Schlaudecker, E. P., Todd, C. A., Poniewierski, M. S., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.31266 · Cited by 27

Influenza Vaccine Effectiveness in Mainland China: A Systematic Review and Meta-Analysis

Yang, X., Zhao, H., Li, Z., Zhu, A., Ren, M., Geng, M., Li, Y., Qin, Y., Feng, L., Peng, Z., et al. (2021) · Vaccines · doi:10.3390/vaccines9020079 · Cited by 27

Decline in Seasonal Influenza Vaccine Effectiveness With Vaccination Program Maturation: A Systematic Review and Meta-analysis

Okoli, G. N., Racovitan, F., Abdulwahid, T., Hyder, S. K., Lansbury, L., Righolt, C. H., Mahmud, S. M., & Nguyen‐Van‐Tam, J. S. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab069 · Cited by 27

High-dose influenza vaccine favors acute plasmablast responses rather than long-term cellular responses

Kim, J. H., Talbot, H. K., Mishina, M., Zhu, Y., Chen, J., Cao, W., Reber, A. J., Griffin, M. R., Shay, D. K., Spencer, S., et al. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.07.018 · Cited by 27

Safety and Immunogenicity of the Heterosubtypic Influenza A Vaccine MVA-NP+M1 Manufactured on the AGE1.CR.pIX Avian Cell Line

Folegatti, P. M., Bellamy, D. G., Flaxman, A. L., Mair, C., Ellis, C., Ramon, R. L., Lopez, F. R., Mitton, C. H., Baker, M., Poulton, I. D., et al. (2019) · Vaccines · doi:10.3390/vaccines7010033 · Cited by 27

Optimising vaccine immunogenicity in ageing populations: key strategies

Jiang, G., Zou, Y., Zhao, D., & Yu, J. (2024) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(24)00497-3 · Cited by 27

Implications of the apparent extinction of B/Yamagata-lineage human influenza viruses

Barr, I., & Subbarao, K. (2024) · npj Vaccines · doi:10.1038/s41541-024-01010-y · Cited by 26

Evaluation of Efficacy Endpoints for a Phase IIb Study of a Respiratory Syncytial Virus Vaccine in Older Adults Using Patient-Reported Outcomes With Laboratory Confirmation

Yu, J. H., Powers, J. H., Vallo, D., & Falloon, J. (2019) · Value in Health · doi:10.1016/j.jval.2019.09.2747 · Cited by 26

A Map of Racial and Ethnic Disparities in Influenza Vaccine Uptake in the Medicare Fee-for-Service Program

Hall, L. L., Xu, L., Mahmud, S. M., Puckrein, G. A., Thommes, E. W., & Chit, A. (2020) · Advances in Therapy · doi:10.1007/s12325-020-01324-y · Cited by 26

Effectiveness of the influenza vaccine at reducing adverse events in patients with heart failure: A systematic review and meta-analysis

Gupta, C., Sachdeva, A., Khamar, J., Bu, C., Bartoszko, J. J., & Loeb, M. B. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.04.039 · Cited by 26

High-Dose Influenza Vaccine Is Associated With Reduced Mortality Among Older Adults With Breakthrough Influenza Even When There Is Poor Vaccine-Strain Match

Chaves, S. S., Naeger, S., Lounaci, K., Zuo, Y., Loiacono, M. M., Pilard, Q., Nealon, J., Genin, M., & Mahé, C. (2023) · Clinical Infectious Diseases · doi:10.1093/cid/ciad322 · Cited by 26

A trivalent, inactivated influenza vaccine (Vaxigrip®): summary of almost 50 years of experience and more than 1.8 billion doses distributed in over 120 countries

Haugh, M. C., Gresset-Bourgeois, V., Macabeo, B., Woods, A., & Samson, S. (2017) · Expert Review of Vaccines · doi:10.1080/14760584.2017.1324302 · Cited by 26

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