Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

DiazGranados, Carlos A., Dunning, Andrew J., Kimmel, Murray, Kirby, Daniel, Treanor, John, Collins, Avi, Pollak, Richard, Christoff, Janet, Earl, John, Landolfi, Victoria, Martin, Earl, Gurunathan, Sanjay, Nathan, Richard, Greenberg, David P., Tornieporth, Nadia G., Decker, Michael D., Talbot, H. Keipp·2014·New England Journal of Medicine
DOI 10.1056/nejmoa1315727

Cited by (878)

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  34. Influenza 2015-2016: Challenges and Recommendations.
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