Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

Prevention and Control of Influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP)

Fiore, A. E., Shay, D. K., Broder, K., Iskander, J. K., Uyeki, T. M., Mootrey, G., Bresee, J. S., & Cox, N. S. (2001) · PsycEXTRA Dataset · doi:10.1037/e548312006-001 · Cited by 5,006 · see citing works

Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

Thompson, W. W., Shay, D. K., Weintraub, E., Brammer, L., Cox, N., Anderson, L. J., & Fukuda, K. (2003) · JAMA · doi:10.1001/jama.289.2.179 · Cited by 3,673 · see citing works

Influenza-Associated Hospitalizations in the United States

Thompson, W. W. (2004) · JAMA · doi:10.1001/jama.292.11.1333 · Cited by 2,213 · see citing works

Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010.

Fiore, A. E., Uyeki, T. M., Broder, K. R., Finelli, L., Euler, G. L., Singleton, J. A., Iskander, J. K., Wortley, P. M., Shay, D. K., Bresee, J., et al. (2009) · PubMed · Cited by 1,964 · see citing works

Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis

Osterholm, M. T., Kelley, N. S., Sommer, A., & Belongia, E. A. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70295-x · Cited by 1,789 · see citing works

The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature

Gross, P. A., Hermogenes, A. W., Sacks, H. S., Lau, J., & Levandowski, R. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-7-199510010-00008 · Cited by 1,100 · see citing works

The Efficacy of Influenza Vaccination in Elderly Individuals

Govaert, T. M. E. (1994) · JAMA · doi:10.1001/jama.1994.03520210045030 · Cited by 883 · see citing works

Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population

Simonsen, L., Reichert, T. A., Viboud, C. G., Blackwelder, W. C., Taylor, R. J., & Miller, M. A. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.3.265 · Cited by 541 · see citing works

Randomized, Double‐Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High‐Dose and Standard‐Dose Influenza Vaccine in Adults 65 Years of Age and Older

Falsey, A. R., Treanor, J. J., Tornieporth, N., Capellan, J., & Gorse, G. J. (2009) · The Journal of Infectious Diseases · doi:10.1086/599790 · Cited by 388 · see citing works

Influenza Activity — United States, 2015–16 Season and Composition of the 2016–17 Influenza Vaccine

Davlin, S. L., Blanton, L., Kniss, K. L., Mustaquim, D., Smith, S., Kramer, N. A., Cohen, J., Cummings, C. N., Garg, S., Flannery, B. L., et al. (2016) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6522a3 · Cited by 328 · see citing works

The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial

Govaert, T. M. (1994) · JAMA · doi:10.1001/jama.272.21.1661 · Cited by 200 · see citing works

Clinical Efficacy and Safety of the Orally Inhaled Neuraminidase Inhibitor Zanamivir in the Treatment of Influenza: a Randomized, Double-blind, Placebo-controlled European Study

Mäkelä, M. J., Pauksens, K., Rostila, T., Fleming, D., Man, C. Y., Keene, O. N., & Webster, A. (2000) · Journal of Infection · doi:10.1053/jinf.1999.0602 · Cited by 179 · see citing works

Seasonal influenza vaccine efficacy and its determinants in children and non-elderly adults: A systematic review with meta-analyses of controlled trials

DiazGranados, C. A., Denis, M., & Plotkin, S. A. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.10.084 · Cited by 171 · see citing works

Effectiveness of Adjuvanted Influenza Vaccination in Elderly Subjects in Northern Italy

Mannino, S., Villa, M., Apolone, G., Weiss, N. S., Groth, N., Aquino, I. F. P., Boldori, L., Caramaschi, F., Gattinoni, A., Malchiodi, G., et al. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kws313 · Cited by 171 · see citing works

The unmet need in the elderly: Designing new influenza vaccines for older adults

McElhaney, J. E. (2005) · Vaccine · doi:10.1016/j.vaccine.2005.04.019 · Cited by 168 · see citing works

The predictive value of influenza symptomatology in elderly people

Govaert, T. M. E. (1998) · Family Practice · doi:10.1093/fampra/15.1.16 · Cited by 168 · see citing works

The Diagnosis of Viral Respiratory Disease in Older Adults

Talbot, H. K., & Falsey, A. R. (2010) · Clinical Infectious Diseases · doi:10.1086/650486 · Cited by 168 · see citing works

AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial

McElhaney, J. E., Beran, J., Devaster, J.-M., Esen, M., Launay, O., Leroux-Roels, G., Ruiz-Palacios, G. M., van Essen, G. A., Caplanusi, A., Claeys, C., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70046-x · Cited by 164 · see citing works

Hemagglutination inhibition assays

CROSS, G. (2002) · Seminars in Avian and Exotic Pet Medicine · doi:10.1053/saep.2002.28236 · Cited by 144 · see citing works

High-dose trivalent influenza vaccine compared to standard dose vaccine in elderly adults: Safety, immunogenicity and relative efficacy during the 2009–2010 season

DiazGranados, C. A., Dunning, A. J., Jordanov, E., Landolfi, V. A., Denis, M., & Talbot, H. K. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.12.013 · Cited by 123 · see citing works

Efficacy and safety of a live attenuated influenza vaccine in adults 60 years of age and older

Villiers, P. J. T. D., Steele, A. D., Hiemstra, L. A., Rappaport, R., Dunning, A. J., Gruber, W. C., & Forrest, B. D. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.09.092 · Cited by 93 · see citing works

Immunogenicity and safety of Fluzone® intradermal and high-dose influenza vaccines in older adults ≥65 years of age: A randomized, controlled, phase II trial

Tsang, P. H., Gorse, G. J., Strout, C. B., Sperling, M. J., Greenberg, D. P., Ozol-Godfrey, A., DiazGranados, C. A., & Landolfi, V. A. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.09.074 · Cited by 91 · see citing works

Seasonal influenza vaccine provision in 157 countries (2004–2009) and the potential influence of national public health policies

Palache, A. M. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.10.030 · Cited by 90 · see citing works

MF59®‐adjuvanted vaccines for seasonal and pandemic influenza prophylaxis

Banzhoff, A., Pellegrini, M., Giudice, G. D., Fragapane, E., Groth, N., & Podda, A. (2008) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2008.00059.x · Cited by 70 · see citing works

Improvement of Inactivated Influenza Virus Vaccines

Couch, R. B., Keitel, W. A., & Cate, T. R. (1997) · The Journal of Infectious Diseases · doi:10.1086/514173 · Cited by 69 · see citing works

Intanza®: a new intradermal vaccine for seasonal influenza

Atmar, R. L., Patel, S. M., & Keitel, W. A. (2010) · Expert Review of Vaccines · doi:10.1586/erv.10.134 · Cited by 59 · see citing works

Re: "Effectiveness of Adjuvanted Influenza Vaccination in Elderly Subjects in Northern Italy"

Skowronski, D. M., Serres, G. D., Janjua, N. Z., & Hottes, T. S. (2013) · American Journal of Epidemiology · doi:10.1093/aje/kwt021 · Cited by 7 · see citing works

Detecting and describing heterogeneity in meta-analysis

Hardy, R. J., & Thompson, S. G. (1998) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(19980430)17:8

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2018–19 Influenza Season

Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Walter, E. B., Fry, A. M., & Jernigan, D. B. (2018) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr6703a1 · Cited by 1,635 · see citing works

Breast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A. E., ELIAS, A. D., Farrar, W. B., Forero, A., Giordano, S. H., et al. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.0012 · Cited by 1,607 · see citing works

A guide to vaccinology: from basic principles to new developments

Pollard, A. J., & Bijker, E. M. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-020-00479-7 · Cited by 1,593 · see citing works

Influenza

Krammer, F., Smith, G. J. D., Fouchier, R. A. M., Peiris, M. J. S., Kedzierska, K., Doherty, P. C., Palese, P., Shaw, M. L., Treanor, J. J., Webster, R. G., et al. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0002-y · Cited by 1,591 · see citing works

Alternatives to antibiotics—a pipeline portfolio review

Czaplewski, L. G., Bax, R. P., Clokie, M. R. J., Dawson, M., Fairhead, H., Fischetti, V. A., Foster, S. J., Gilmore, B., Hancock, R. E. W., Harper, D. J., et al. (2016) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(15)00466-1 · Cited by 846 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines

Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Olsen, S. J., Karron, R. A., Jernigan, D. B., & Bresee, J. (2016) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr6505a1 · Cited by 597 · see citing works

Advances in the development of influenza virus vaccines

Krammer, F., & Palese, P. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4529 · Cited by 592 · see citing works

Age-dependent Immune Response to the Biontech/Pfizer BNT162b2 Coronavirus Disease 2019 Vaccination

Müller, L., Andrée, M., Moskorz, W., Drexler, I., Walotka, L., Grothmann, R., Ptok, J., Hillebrandt, J., Ritchie, A., Rabl, D., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab381 · Cited by 511 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2019–20 Influenza Season

Grohskopf, L. A., Alyanak, E., Broder, K. R., Walter, E. B., Fry, A. M., & Jernigan, D. B. (2019) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr6803a1 · Cited by 393 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2017–18 Influenza Season

Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Walter, E. B., Bresee, J., Fry, A. M., & Jernigan, D. B. (2017) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr6602a1 · Cited by 390 · see citing works

The disease burden of influenza beyond respiratory illness

Macías, A. E., McElhaney, J. E., Chaves, S. S., Nealon, J., Nunes, M. C., Samson, S., Seet, B. T., Weinke, T., & Yu, H. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.09.048 · Cited by 371 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 Influenza Season

Grohskopf, L. A., Alyanak, E., Ferdinands, J. M., Broder, K. R., Blanton, L., Talbot, H. K., & Fry, A. M. (2021) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr7005a1 · Cited by 364 · see citing works

Successful and Maladaptive T Cell Aging

Goronzy, J. J., & Weyand, C. M. (2017) · Immunity · doi:10.1016/j.immuni.2017.03.010 · Cited by 362 · see citing works

Applications of gold nanoparticles in virus detection

Draz, M. S., & Shafiee, H. (2018) · Theranostics · doi:10.7150/thno.23856 · Cited by 351 · see citing works

Prevention and control of seasonal influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2020-21 influenza season

Grohskopf, L. A., Alyanak, E., Broder, K. R., Blanton, L. H., Fry, A. M., Jernigan, D. B., & Atmar, R. L. (2020) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6908a1 · Cited by 332 · see citing works

Prevention and Control of Seasonal Influenza With Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2017–18 Influenza Season

Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Walter, E. B., Bresee, J., Fry, A. M., & Jernigan, D. B. (2017) · American Journal of Transplantation · doi:10.1111/ajt.14511 · Cited by 327 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022–23 Influenza Season

Grohskopf, L. A., Blanton, L., Ferdinands, J. M., Chung, J. R., Broder, K. R., Talbot, H. K., Morgan, R. L., & Fry, A. M. (2022) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr7101a1 · Cited by 327 · see citing works

Next-generation influenza vaccines: opportunities and challenges

Wei, C., Crank, M. C., Shiver, J. W., Graham, B. S., Mascola, J. R., & Nabel, G. J. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0056-x · Cited by 324 · see citing works

Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season

Rolfes, M. A. R., Flannery, B. L., Chung, J. R., O’Halloran, A. C., Garg, S., Belongia, E. A., Gaglani, M., Zimmerman, R. K., Jackson, M. L., Monto, A. S., et al. (2019) · Clinical Infectious Diseases · doi:10.1093/cid/ciz075 · Cited by 298 · see citing works

Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older

Dunkle, L. M., Izikson, R., PATRIARCA, P. A., Goldenthal, K. L., Muse, D. D., Callahan, J. D., & Cox, M. M. J. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1608862 · Cited by 290 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2024–25 Influenza Season

Grohskopf, L. A., Ferdinands, J. M., Blanton, L., Broder, K. R., & Loehr, J. (2024) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr7305a1 · Cited by 282 · see citing works

Influenza Vaccine Effectiveness in the United States during the 2015–2016 Season

Jackson, M. L., Chung, J. R., Jackson, L. A., Phillips, C. H., Benoit, J., Monto, A. S., Martin, E. T., Belongia, E. A., McLean, H. Q., Gaglani, M., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1700153 · Cited by 277 · see citing works

Mortality Associated With Influenza and Respiratory Syncytial Virus in the US, 1999-2018

Hansen, C., Chaves, S. S., Demont, C., & Viboud, C. G. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.0527 · Cited by 250 · see citing works

Assessment of the Inclusion of Racial/Ethnic Minority, Female, and Older Individuals in Vaccine Clinical Trials

Flores, L. E., Frontera, W. R., Andrasik, M. P., del Rı́o, C., González, A. M., Price, S. A., Krantz, E. M., Pergam, S. A., & Silver, J. K. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.37640 · Cited by 244 · see citing works

Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines

Sridhar, S., Brokstad, K. A., & Cox, R. J. (2015) · Vaccines · doi:10.3390/vaccines3020373 · Cited by 206 · see citing works

Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology

Denlinger, C. S., Sanft, T., Baker, K. S., Broderick, G., Demark-Wahnefried, W., Friedman, D. L., Goldman, M., Hudson, M., Khakpour, N., King, A., et al. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.0078 · Cited by 199 · see citing works

The Impact of Pre-existing Comorbidities and Therapeutic Interventions on COVID-19

Callender, L. A., Curran, M., Bates, S. M., Mairesse, M., Weigandt, J., & Betts, C. J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01991 · Cited by 190 · see citing works

Practical Guide to Vaccination in All Stages of CKD, Including Patients Treated by Dialysis or Kidney Transplantation

Krueger, K., Ison, M. G., & Ghossein, C. (2019) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2019.06.014 · Cited by 188 · see citing works

Viral vectors as vaccine platforms: from immunogenicity to impact

Ewer, K., Lambe, T., Rollier, C. S., Spencer, A. J., Hill, A. V. S., & Dorrell, L. (2016) · Current Opinion in Immunology · doi:10.1016/j.coi.2016.05.014 · Cited by 187 · see citing works

An Overview of Influenza Viruses and Vaccines

Nuwarda, R. F., Alharbi, A. A., & Kayser, V. (2021) · Vaccines · doi:10.3390/vaccines9091032 · Cited by 185 · see citing works

A Double-Blind, Randomized Trial of High-Dose vs Standard-Dose Influenza Vaccine in Adult Solid-Organ Transplant Recipients

Natori, Y., Shiotsuka, M., Slomovic, J., Höschler, K., Ferreira, V. H., Ashton, P., Rotstein, C., Lilly, L. B., Schiff, J. R., Singer, L. G., et al. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix1082 · Cited by 184 · see citing works

Comparative effectiveness of high-dose versus standard-dose influenza vaccines in US residents aged 65 years and older from 2012 to 2013 using Medicare data: a retrospective cohort analysis

Izurieta, H. S., Thadani, N. N., Shay, D. K., Lu, Y., Maurer, A., Foppa, I., Franks, R. L., Pratt, D., Forshee, R. A., MaCurdy, T. E., et al. (2015) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(14)71087-4 · Cited by 181 · see citing works

Comparative effectiveness of high-dose versus standard-dose influenza vaccination on numbers of US nursing home residents admitted to hospital: a cluster-randomised trial

Gravenstein, S., Davidson, H. E., Taljaard, M., Ogarek, J. A., Gozalo, P. L., Han, L., & Mor, V. (2017) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(17)30235-7 · Cited by 178 · see citing works

Efficacy and safety of high-dose influenza vaccine in elderly adults: A systematic review and meta-analysis

Wilkinson, K., Wei, Y., Szwajcer, A., Rabbani, R., Zarychanski, R., Abou-Setta, A. M., & Mahmud, S. M. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.03.092 · Cited by 172 · see citing works

The immune response to influenza in older humans: beyond immune senescence

McElhaney, J. E., Verschoor, C. P., Andrew, M. K., Haynes, L., Kuchel, G. A., & Pawelec, G. (2020) · Immunity & Ageing · doi:10.1186/s12979-020-00181-1 · Cited by 168 · see citing works

Clinical epidemiology of infectious disease among patients with chronic kidney disease

Ishigami, J., & Matsushita, K. (2018) · Clinical and Experimental Nephrology · doi:10.1007/s10157-018-1641-8 · Cited by 166 · see citing works

Vaccines for the elderly: current use and future challenges

Weinberger, B. (2018) · Immunity & Ageing · doi:10.1186/s12979-017-0107-2 · Cited by 164 · see citing works

Relative Effectiveness of Cell-Cultured and Egg-Based Influenza Vaccines Among Elderly Persons in the United States, 2017–2018

Izurieta, H. S., Chillarige, Y., Kelman, J. A., Wei, Y., Lu, Y., Xu, W., Lu, M., Pratt, D., Chu, S., Wernecke, M., et al. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiy716 · Cited by 164 · see citing works

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023–24 Influenza Season

Grohskopf, L. A., Blanton, L., Ferdinands, J. M., Chung, J. R., Broder, K. R., & Talbot, H. K. (2023) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr7202a1 · Cited by 157 · see citing works

Duration of Influenza Vaccine Effectiveness: A Systematic Review, Meta-analysis, and Meta-regression of Test-Negative Design Case-Control Studies

Young, B. E., Sadarangani, S. P., Jiang, L., Wilder‐Smith, A., & Chen, M. I.-C. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix632 · Cited by 152 · see citing works

The Covid-19 Vaccine-Development Multiverse

Heaton, P. M. (2020) · New England Journal of Medicine · doi:10.1056/nejme2025111 · Cited by 151 · see citing works

Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: a systematic review and meta-analysis

Lee, J. K. H., Lam, G., Shin, T., Kim, J., Krishnan, A., Greenberg, D. P., & Chit, A. (2018) · Expert Review of Vaccines · doi:10.1080/14760584.2018.1471989 · Cited by 143 · see citing works

Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses

Crooke, S. N., Ovsyannikova, I. G., Poland, G. A., & Kennedy, R. B. (2019) · Experimental Gerontology · doi:10.1016/j.exger.2019.110632 · Cited by 143 · see citing works

Vaccination of Adults With Cancer: ASCO Guideline

Kamboj, M., Bohlke, K., Manassaram‐Baptiste, D., Dunleavy, K. M., Fueger, A., Jones, L., Kelkar, A. H., Law, L. Y., LeFebvre, K. B., Ljungman, P. T., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.24.00032 · Cited by 143 · see citing works

Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals

Henry, C., Zheng, N., Huang, M., Cabanov, A., Rojas, K. T., Kaur, K., Andrews, S. F., Palm, A.-K. E., Chen, Y.-Q., Li, Y., et al. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.01.002 · Cited by 142 · see citing works

T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines

McElhaney, J. E., Kuchel, G. A., Zhou, X., Swain, S. L., & Haynes, L. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00041 · Cited by 139 · see citing works

Effect of High-Dose Trivalent vs Standard-Dose Quadrivalent Influenza Vaccine on Mortality or Cardiopulmonary Hospitalization in Patients With High-risk Cardiovascular Disease

Vardeny, O., Kim, K., Udell, J. A., Joseph, J., Desai, A. S., Farkouh, M. E., Hegde, S. M., Hernandez, A. F., McGeer, A., Talbot, H. K., et al. (2020) · JAMA · doi:10.1001/jama.2020.23649 · Cited by 139 · see citing works

How I vaccinate blood and marrow transplant recipients

Carpenter, P. A., & Englund, J. A. (2016) · Blood · doi:10.1182/blood-2015-12-550475 · Cited by 138 · see citing works

Safety, efficacy, and immunogenicity of Flublok in the prevention of seasonal influenza in adults

Cox, M. M. J., Izikson, R., Post, P. L., & Dunkle, L. M. (2015) · Therapeutic Advances in Vaccines · doi:10.1177/2051013615595595 · Cited by 136 · see citing works

Inactivated influenza vaccines

Fiore, A. E., Bridges, C. B., Katz, J. M., & Cox, N. J. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-0090-5.00026-4 · Cited by 135 · see citing works

Aging and influenza vaccine-induced immunity

Dugan, H. L., Henry, C., & Wilson, P. C. (2019) · Cellular Immunology · doi:10.1016/j.cellimm.2019.103998 · Cited by 133 · see citing works

Efficacy and effectiveness of high-dose influenza vaccine in older adults by circulating strain and antigenic match: An updated systematic review and meta-analysis

Lee, J. K. H., Lam, G., Shin, T., Samson, S., Greenberg, D. P., & Chit, A. (2021) · Vaccine · doi:10.1016/j.vaccine.2020.09.004 · Cited by 128 · see citing works

Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults

Pillet, S., Couillard, J., Trépanier, S., Poulin, J., Yassine‐Diab, B., Guy, B., Ward, B. J., & Landry, N. (2019) · PLoS ONE · doi:10.1371/journal.pone.0216533 · Cited by 127 · see citing works

Immunology of the ageing kidney

Sato, Y., & Yanagita, M. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0185-9 · Cited by 126 · see citing works

Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

Kim, C., Hu, B., Jadhav, R. R., Jin, J., Zhang, H., Cavanagh, M., Akondy, R. S., Ahmed, R., Weyand, C. M., & Goronzy, J. J. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.10.074 · Cited by 123 · see citing works

Host Factors Impact Vaccine Efficacy: Implications for Seasonal and Universal Influenza Vaccine Programs

Dhakal, S., & Klein, S. L. (2019) · Journal of Virology · doi:10.1128/jvi.00797-19 · Cited by 123 · see citing works

Vaccines to Prevent Infectious Diseases in the Older Population: Immunological Challenges and Future Perspectives

Wagner, A., & Weinberger, B. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00717 · Cited by 123 · see citing works

Pneumonia in Patients with Chronic Obstructive Pulmonary Disease

Restrepo, M. I., Sibila, O., & Anzueto, A. (2018) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2018.0030 · Cited by 122 · see citing works

Prevention of serious events in adults 65 years of age or older: A comparison between high-dose and standard-dose inactivated influenza vaccines

DiazGranados, C. A., Robertson, C. A., Talbot, H. K., Landolfi, V. A., Dunning, A. J., & Greenberg, D. P. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.07.006 · Cited by 122 · see citing works

Respiratory viral infections in the elderly

Watson, A., & Wilkinson, T. M. A. (2021) · Therapeutic Advances in Respiratory Disease · doi:10.1177/1753466621995050 · Cited by 118 · see citing works

Analysis of COVID‐19 vaccines: Types, thoughts, and application

Han, X., Xu, P., & Ye, Q. (2021) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.23937 · Cited by 114 · see citing works

Comparative Immunogenicity of Several Enhanced Influenza Vaccine Options for Older Adults: A Randomized, Controlled Trial

Cowling, B. J., Perera, R. A. P. M., Valkenburg, S. A., Leung, N. H. L., Iuliano, A. D., Tam, Y. H., Wong, J. H. F., Fang, V. J., Li, A. P. Y., So, H. C., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciz1034 · Cited by 110 · see citing works

Safety and immunogenicity of a high-dose quadrivalent influenza vaccine administered concomitantly with a third dose of the mRNA-1273 SARS-CoV-2 vaccine in adults aged ≥65 years: a phase 2, randomised, open-label study

Izikson, R., Brune, D., Bolduc, J.-S., Bourron, P., Fournier, M., Moore, T. M., Pandey, A., Perez, L., Sater, N., Shrestha, A., et al. (2021) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(21)00557-9 · Cited by 108 · see citing works

Do antibody responses to the influenza vaccine persist year-round in the elderly? A systematic review and meta-analysis

Young, B. E., Zhao, X., Cook, A. R., Parry, C. M., Wilder‐Smith, A., & Chen, M. I.-C. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.11.013 · Cited by 106 · see citing works

Comparative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccines Among US Medicare Beneficiaries in Preventing Postinfluenza Deaths During 2012–2013 and 2013–2014

Shay, D. K., Chillarige, Y., Kelman, J. A., Forshee, R. A., Foppa, I., Wernecke, M., Lu, Y., Ferdinands, J. M., Iyengar, A., Fry, A. M., et al. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw641 · Cited by 106 · see citing works

Influenza vaccination: protecting the most vulnerable

Tanner, A. R., Dorey, R. B., Brendish, N. J., & Clark, T. W. (2021) · European Respiratory Review · doi:10.1183/16000617.0258-2020 · Cited by 106 · see citing works

Influenza Vaccination

Treanor, J. J. (2016) · New England Journal of Medicine · doi:10.1056/nejmcp1512870 · Cited by 104 · see citing works

Host factors and vaccine efficacy: Implications for COVID‐19 vaccines

Falahi, S., & Kenarkoohi, A. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27485 · Cited by 103 · see citing works

Correlates of Protection against Influenza in the Elderly: Results from an Influenza Vaccine Efficacy Trial

Dunning, A. J., DiazGranados, C. A., Voloshen, T., Hu, B. T., Landolfi, V. A., & Talbot, H. K. (2016) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00604-15 · Cited by 101 · see citing works

Overcoming immune dysfunction in the elderly: trained immunity as a novel approach

Bulut, O., Kilic, G., Domínguez-Andrés, J., & Netea, M. G. (2020) · International Immunology · doi:10.1093/intimm/dxaa052 · Cited by 99 · see citing works

Challenges of Making Effective Influenza Vaccines

Gouma, S., Anderson, E. M., & Hensley, S. E. (2020) · Annual Review of Virology · doi:10.1146/annurev-virology-010320-044746 · Cited by 95 · see citing works

The influence of prebiotic or probiotic supplementation on antibody titers after influenza vaccination: A systematic review and meta-analysis of randomized controlled trials

Yeh, T.-L., Shih, P.-C., Liu, S.-J., Lin, C.-H., Liu, J.-M., Lei, W.-T., & Lin, C.-Y. (2018) · Drug Design Development and Therapy · doi:10.2147/dddt.s155110 · Cited by 93 · see citing works

How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation

Waghmare, A., Englund, J. A., & Boeckh, M. (2016) · Blood · doi:10.1182/blood-2016-01-634873 · Cited by 93 · see citing works

Fighting against a protean enemy: immunosenescence, vaccines, and healthy aging

Giudice, G. D., Goronzy, J. J., Grubeck‐Loebenstein, B., Lambert, P., Mrkvan, T., Stoddard, J. J., & Doherty, T. M. (2017) · npj Aging and Mechanisms of Disease · doi:10.1038/s41514-017-0020-0 · Cited by 91 · see citing works

Efficacy and immunogenicity of high-dose influenza vaccine in older adults by age, comorbidities, and frailty

DiazGranados, C. A., Dunning, A. J., Robertson, C. A., Talbot, H. K., Landolfi, V. A., & Greenberg, D. P. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.07.003 · Cited by 90 · see citing works

South African guideline for the management of community-acquired pneumonia in adults

South African Thoracic Society, F. O. I. D. S. O. S. A., Boyles, T. H., Brink, A. J., Calligaro, G., Cohen, C., Dheda, K. U. J., Maartens, G., Richards, G. A., van Zyl-Smit, R. N., Smith, C. A., et al. (2017) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.05.31 · Cited by 89 · see citing works

Does Vitamin D Deficiency Affect the Immunogenic Responses to Influenza Vaccination? A Systematic Review and Meta-Analysis

Lee, M.-D., Lin, C., Lei, W., Chang, H.-Y., Lee, H., Yeung, C., Chiu, N., Chi, H., Liu, J., Hsu, R., et al. (2018) · Nutrients · doi:10.3390/nu10040409 · Cited by 89 · see citing works

An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus

Schwartzman, L. M., Cathcart, A. L., Pujanauski, L. M., Qi, L., Kash, J. C., & Taubenberger, J. K. (2015) · mBio · doi:10.1128/mbio.01044-15 · Cited by 89 · see citing works

Relative Effectiveness of Influenza Vaccines Among the United States Elderly, 2018–2019

Izurieta, H. S., Chillarige, Y., Kelman, J. A., Wei, Y., Lu, Y., Xu, W., Lu, M., Pratt, D., Wernecke, M., MaCurdy, T. E., et al. (2020) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa080 · Cited by 86 · see citing works

Geriatric Infectious Diseases: Current Concepts on Diagnosis and Management

Yoshikawa, T. T., & Norman, D. C. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14731 · Cited by 85 · see citing works

Earliest infections predict the age distribution of seasonal influenza A cases

Arevalo, P., McLean, H. Q., Belongia, E. A., & Cobey, S. E. (2020) · eLife · doi:10.7554/elife.50060 · Cited by 85 · see citing works

Challenges in adult vaccination

de Gomensoro, E., Giudice, G. D., & Doherty, T. M. (2018) · Annals of Medicine · doi:10.1080/07853890.2017.1417632 · Cited by 85 · see citing works

Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient

Fontana, L., & Strasfeld, L. M. (2019) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2019.02.004 · Cited by 85 · see citing works

Seasonal Influenza Vaccination in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib

Sun, C., Gao, J., Couzens, L. K., Tian, X., Farooqui, M. Z. H., Eichelberger, M. C., & Wiestner, A. U. (2016) · JAMA Oncology · doi:10.1001/jamaoncol.2016.2437 · Cited by 84 · see citing works

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice

Silva-Cayetano, A., Foster, W. S., Innocentin, S., Belij-Rammerstorfer, S., Spencer, A. J., Burton, O. T., Fra-Bidó, S., Le Lee, J., Thakur, N., Conceicao, C., et al. (2021) · Med · doi:10.1016/j.medj.2020.12.006 · Cited by 84 · see citing works

Influenza Vaccines: Successes and Continuing Challenges

Becker, T., Elbahesh, H., Reperant, L. A., Rimmelzwaan, G. F., & Osterhaus, A. D. M. E. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiab269 · Cited by 83 · see citing works

HIV infection Worsens Age-Associated Defects in Antibody Responses to Influenza Vaccine

George, V. K., Pallikkuth, S., Parmigiani, A., Alcaide, M. L., Fischl, M. A., Arheart, K. L., & Pahwa, S. G. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu840 · Cited by 81 · see citing works

Influenza Vaccine Effectiveness: New Insights and ChallengesPreprint

McLean, H. Q., & Belongia, E. A. (2020) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a038315 · Cited by 80 · see citing works

Comparison of the safety and immunogenicity of a novel Matrix-M-adjuvanted nanoparticle influenza vaccine with a quadrivalent seasonal influenza vaccine in older adults: a phase 3 randomised controlled trial

Shinde, V., Cho, I., Plested, J. S., Agrawal, S., Fiske, J., Cai, R., Zhou, H., Pham, X., Zhu, M., Cloney-Clark, S., et al. (2021) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(21)00192-4 · Cited by 79 · see citing works

Development and deployment of COVID-19 vaccines for those most vulnerable

Koff, W. C., Schenkelberg, T., Williams, T. M., Baric, R. S., McDermott, A. B., Cameron, C., Cameron, M. J., Frieman, M. B., Neumann, G., Kawaoka, Y., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abd1525 · Cited by 78 · see citing works

Safety and immunogenicity of high-dose quadrivalent influenza vaccine in adults ≥65 years of age: A phase 3 randomized clinical trial

Chang, L.-J., Meng, Y., Janosczyk, H., Landolfi, V. A., & Talbot, H. K. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.08.016 · Cited by 77 · see citing works

Influenza Vaccination in Older Adults: Recent Innovations and Practical Applications

Andrew, M. K., Bowles, S. K., Pawelec, G., Haynes, L., Kuchel, G. A., McNeil, S., & McElhaney, J. E. (2018) · Drugs & Aging · doi:10.1007/s40266-018-0597-4 · Cited by 76 · see citing works

Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations

Sullivan, S. G., Price, O. H., & Regan, A. K. (2019) · Therapeutic Advances in Vaccines and Immunotherapy · doi:10.1177/2515135519826481 · Cited by 76 · see citing works

Randomized, double‐blind comparison of standard‐dose vs. high‐dose trivalent inactivated influenza vaccine in pediatric solid organ transplant patients

GiaQuinta, S., Michaels, M. G., McCullers, J. A., Wang, L., Fonnesbeck, C., O’Shea, A., Green, M., & Halasa, N. (2014) · Pediatric Transplantation · doi:10.1111/petr.12419 · Cited by 76 · see citing works

Comparative immunogenicity of enhanced seasonal influenza vaccines in older adults: a systematic review and meta-analysis

Ng, T. W. Y., Cowling, B. J., Gao, H., & Thompson, M. G. (2018) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiy720 · Cited by 75 · see citing works

Vaccine Immunology

Siegrist, C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35761-6.00002-x · Cited by 75 · see citing works

Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection

Merani, S., Pawelec, G., Kuchel, G. A., & McElhaney, J. E. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00784 · Cited by 74 · see citing works

Analysis of MarketScan Data for Immunosuppressive Conditions and Hospitalizations for Acute Respiratory Illness, United States

Patel, M. M., Chen, J., Kim, S. S., Garg, S., Flannery, B. L., Haddadin, Z., Rankin, D. A., Halasa, N., Talbot, H. K., & Reed, C. (2020) · Emerging infectious diseases · doi:10.3201/eid2608.191493 · Cited by 74 · see citing works

Influenza Vaccination to Reduce Cardiovascular Morbidity and Mortality in Patients With COVID-19

Behrouzi, B., Campoverde, M. V. A., Liang, K., Talbot, H. K., Bogoch, I. I., McGeer, A., Fröbert, O., Loeb, M. B., Vardeny, O., Solomon, S. D., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.08.028 · Cited by 74 · see citing works

High Doses of Inactivated African Swine Fever Virus Are Safe, but Do Not Confer Protection against a Virulent Challenge

Cadenas-Fernández, E., Sánchez‐Vizcaíno, J. M., van den Born, E., Kosowska, A., van Kilsdonk, E., Fernández‐Pacheco, P., Gallardo, C., Arias, M., & Barasona, J. Á. (2021) · Vaccines · doi:10.3390/vaccines9030242 · Cited by 74 · see citing works

Safety and immunogenicity of high-dose trivalent inactivated influenza vaccine in adults 50–64 years of age

DiazGranados, C. A., Saway, W., Gouaux, J., Baron, M., Baker, J. P., Denis, M., Jordanov, E., Landolfi, V. A., & Yau, E. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.10.131 · Cited by 22 · see citing works

Randomized, Double‐Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High‐Dose and Standard‐Dose Influenza Vaccine in Adults 65 Years of Age and Older

Falsey, A. R., Treanor, J. J., Tornieporth, N., Capellan, J., & Gorse, G. J. (2009) · The Journal of Infectious Diseases · doi:10.1086/599790 · Cited by 388 · see citing works

Relative effectiveness of high dose versus standard dose influenza vaccines in older adult outpatients over four seasons, 2015–16 to 2018–19

Balasubramani, G. K., Choi, W. S., Nowalk, M. P., Zimmerman, R. K., Monto, A. S., Martin, E. T., Belongia, E. A., McLean, H. Q., Gaglani, M., Murthy, K., et al. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.08.011 · Cited by 23 · see citing works

High-dose trivalent influenza vaccine compared to standard dose vaccine in elderly adults: Safety, immunogenicity and relative efficacy during the 2009–2010 season

DiazGranados, C. A., Dunning, A. J., Jordanov, E., Landolfi, V. A., Denis, M., & Talbot, H. K. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.12.013 · Cited by 123 · see citing works

High-dose trivalent influenza vaccine. Efficacy and effectiveness

de Miguel, Á. G., Margüello, E. R., Díez‐Domingo, J., de Lejarazu, R. O., Martinón‐Torres, F., & Departamento de Medicina Preventiva y Salud Pública, U. R. J. C. (2020) · Revista Española de Quimioterapia · doi:10.37201/req/043.2020 · Cited by 6 · see citing works