The DOI matches its Crossref record.
A Variegated Squirrel Bornavirus Associated with Fatal Human Encephalitis
Open accessAbstract
Between 2011 and 2013, three breeders of variegated squirrels (Sciurus variegatoides) had encephalitis with similar clinical signs and died 2 to 4 months after onset of the clinical symptoms. With the use of a metagenomic approach that incorporated next-generation sequencing and real-time reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR), the presence of a previously unknown bornavirus was detected in a contact squirrel and in brain samples from the three patients. Phylogenetic analyses showed that this virus, tentatively named variegated squirrel 1 bornavirus (VSBV-1), forms a lineage separate from that of the known bornavirus species. (Funded by the Federal Ministry of Food and Agriculture [Germany] and others.).
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Citations
Cited by
Simner, P. J., Miller, S., & Carroll, K. C. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/cix881 · Cited by 821
The Diagnosis and Treatment of Autoimmune Encephalitis
Lancaster, E. (2016) · Journal of Clinical Neurology · doi:10.3988/jcn.2016.12.1.1 · Cited by 437
mNGS in clinical microbiology laboratories: on the road to maturity
Han, D., Li, Z., Li, R., Tan, P., Zhang, R., & Li, J. (2019) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2019.1681933 · Cited by 361
Goldberg, B., Sichtig, H., Geyer, C., Ledeboer, N., & Weinstock, G. M. (2015) · mBio · doi:10.1128/mbio.01888-15 · Cited by 360
Clinical and biological insights from viral genome sequencing
Houldcroft, C. J., Beale, M. A., & Breuer, J. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.182 · Cited by 334
Metadata
- Authors
- Hoffmann, B., Tappe, D., Höper, D., Herden, C., Boldt, A., Mawrin, C., Niederstraßer, O., Müller, T., Jenckel, M., van der Grinten, E., Lutter, C., Abendroth, B., Teifke, J. P., Cadar, D., Schmidt-Chanasit, J., Ulrich, R. G., & Beer, M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-07-09
- Volume
- 373
- Issue
- 2
- Pages
- 154-162
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1269781284
- Cited by
- 260
- References
- 0
- FWCI
- 40.24
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Hoffmann, B., Tappe, D., Höper, D., Herden, C., Boldt, A., Mawrin, C., Niederstraßer, O., Müller, T., Jenckel, M., van der Grinten, E., Lutter, C., Abendroth, B., Teifke, J. P., Cadar, D., Schmidt-Chanasit, J., Ulrich, R. G., & Beer, M. (2015). A Variegated Squirrel Bornavirus Associated with Fatal Human Encephalitis. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1415627
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
