The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest
Open accessAbstract
BACKGROUND: Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led the International Liaison Committee on Resuscitation to call for a placebo-controlled trial to determine whether the use of epinephrine is safe and effective in such patients. METHODS: In a randomized, double-blind trial involving 8014 patients with out-of-hospital cardiac arrest in the United Kingdom, paramedics at five National Health Service ambulance services administered either parenteral epinephrine (4015 patients) or saline placebo (3999 patients), along with standard care. The primary outcome was the rate of survival at 30 days. Secondary outcomes included the rate of survival until hospital discharge with a favorable neurologic outcome, as indicated by a score of 3 or less on the modified Rankin scale (which ranges from 0 [no symptoms] to 6 [death]). RESULTS: At 30 days, 130 patients (3.2%) in the epinephrine group and 94 (2.4%) in the placebo group were alive (unadjusted odds ratio for survival, 1.39; 95% confidence interval [CI], 1.06 to 1.82; P=0.02). There was no evidence of a significant difference in the proportion of patients who survived until hospital discharge with a favorable neurologic outcome (87 of 4007 patients [2.2%] vs. 74 of 3994 patients [1.9%]; unadjusted odds ratio, 1.18; 95% CI, 0.86 to 1.61). At the time of hospital discharge, severe neurologic impairment (a score of 4 or 5 on the modified Rankin scale) had occurred in more of the survivors in the epinephrine group than in the placebo group (39 of 126 patients [31.0%] vs. 16 of 90 patients [17.8%]). CONCLUSIONS: In adults with out-of-hospital cardiac arrest, the use of epinephrine resulted in a significantly higher rate of 30-day survival than the use of placebo, but there was no significant between-group difference in the rate of a favorable neurologic outcome because more survivors had severe neurologic impairment in the epinephrine group. (Funded by the U.K. National Institute for Health Research and others; Current Controlled Trials number, ISRCTN73485024 .).
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In contrast, a strict requirement for pre-enrolment consent may delay the initiation of an experimental intervention, thereby hampering its potential benefit to the patient. 327”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [327]
Citations
Cites
Heart disease and stroke statistics-2018 update: a report from the american heart association
Benjamin, E. J., Virani, S. S., Callaway, C. W., Chamberlain, A. M., Chang, A. R., Cheng, S., Chiuve, S. E., Cushman, M., Delling, F. N., Deo, R., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000558 · Cited by 7,146
Nolan, J. P., Soar, J., Cariou, A., Cronberg, T., Moulaert, V. R. M., Deakin, C. D., Böttiger, B. W., Friberg, H., Sunde, K., & Sandroni, C. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2015.07.018 · Cited by 1,139
Self-citationEarly Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest
Hasselqvist‐Ax, I., Riva, G., Herlitz, J. D., Rosenqvist, M., Hollenberg, J., Nordberg, P., Ringh, M., Jonsson, M. N., Axelsson, C., Lindqvist, J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1405796 · Cited by 992
Mode of death after admission to an intensive care unit following cardiac arrest
Laver, S. R., Farrow, C., Turner, D., & Nolan, J. P. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2425-z · Cited by 984
Self-citationEuropean Resuscitation Council Guidelines for Resuscitation 2015
Monsieurs, K. G., Nolan, J. P., Bossaert, L. L., Greif, R., Maconochie, I. K., Nikolaou, N. I., Perkins, G. D., Soar, J., Truhlář, A., Wyllie, J. P., et al. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2015.07.038 · Cited by 962
Self-citationPerkins, G. D., Jacobs, I. G., Nadkarni, V. M., Berg, R. A., Bhanji, F., Biarent, D., Bossaert, L. L., Brett, S. J., Chamberlain, D., de Caen, A. R., et al. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2014.11.002 · Cited by 726
Self-citationJacobs, I. G., Finn, J., Jelinek, G. A., Oxer, H. F., & Thompson, P. L. (2011) · Resuscitation · doi:10.1016/j.resuscitation.2011.06.029 · Cited by 472
Self-citationHypoxic-ischemic brain injury: Pathophysiology, neuropathology and mechanisms
Busl, K. M., & Greer, D. M. (2010) · Neurorehabilitation · doi:10.3233/nre-2010-0531 · Cited by 368
Public-Access Defibrillation and Out-of-Hospital Cardiac Arrest in Japan
Kitamura, T., Kiyohara, K., Sakai, T., Matsuyama, T., Hatakeyama, T., Shimamoto, T., Izawa, J., Fujii, T., Nishiyama, C., Kawamura, T., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmsa1600011 · Cited by 332
Validation of a Rule for Termination of Resuscitation in Out-of-Hospital Cardiac Arrest
Morrison, L. J., Visentin, L. M., Kiss, A., Theriault, R., Eby, D., Vermeulen, M. J., Sherbino, J., & Verbeek, P. R. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052620 · Cited by 325
Research works printed but not linked: 1
- Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care. 6. Advanced cardiovascular life support: section 6: pharmacology II: agents to optimize cardiac output and blood pressure. Circulation 2000;102:Suppl:I-129–I-135.10966670
Cited by
Sorted by citations
Items 601–700 of 797
The fight against time in prehospital cardiac arrest - a true medical emergency
Holmen, J. (2020) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Role of Vasopressors in Cardiac Arrest
Morrison, L. J. (2020) · Critical Care Clinics · doi:10.1016/j.ccc.2020.07.009
The limitations of evidence: increasing data and increasing doubt in the treatment of cardiac arrest
Berg, K. M. (2020) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000765
Free Open Access Medical Education (FOAM) and its relevance to military clinicians
Winstanley, M., Henning, D. C., & Gurney, I. (2018) · Journal of The Royal Naval Medical Service · doi:10.1136/jrnms-104-192
The ineffable epinephrine in the labyrinth of evidence-based medicine
Orso, D., Peric, D., Federici, N., Piani, T., Deana, C., Vetrugno, L., & Bove, T. (2020) · European Journal of Emergency Medicine · doi:10.1097/mej.0000000000000780
Steventon, N. B. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780192888501.003.0005
Baldwin, A., & Myers, G. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0015
Out-of-hospital cardiac arrest
Nolan, J. P., & Hassager, C. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198849346.003.0009
Self-citationParo cardiaco de origen traumático: ¿cómo podemos intervenir en el servicio de urgencias?
Gómez, M. Z., Quintero, C. C. A., & Palacio, S. P. (2021) · Medicina UPB · doi:10.18566/medupb.v40n1.a07
Optimizing the management of inpatient cardiac arrest
Carter, M. (2021) · JAAPA · doi:10.1097/01.jaa.0000735736.00078.d9
Focused ultrasound in out-of-hospital cardiac arrest by advanced paramedics
Brown, N., Fothergill, R. T., McIntyre, I., Faulkner, M., & Quinn, T. (2021) · International Paramedic Practice · doi:10.12968/ippr.2021.11.2.49
Self-citationWijland, Y. (2021) · Australasian Journal of Paramedicine · doi:10.33151/ajp.18.890
Out‐of‐hospital cardiac arrest research
Grunau, B. E., Smith, K. L., & Panchal, A. R. (2021) · Emergency medical services · doi:10.1002/9781119756279.ch117
Adrénaline au cours de la réanimation de l’arrêt cardiaque
Dumas, F., & Cariou, A. (2021) · Annales françaises de médecine d’urgence · doi:10.3166/afmu-2021-0335
Awad, E. (2021) · cIRcle (University of British Columbia) · doi:10.14288/1.0402152
Huang, H.-C., Lee, T.-Y., Tsai, C.-H., Su, Y.-S., Chen, Y., Yeh, Y.-N., Hsu, C.-F., & Tsai, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182111020
Впровадження постійного тренінгового навчання з серцево-легеневої реанімації серед лікарів-інтернів
Распутіна, Л. В., Ткаченко, Т. В., & Откаленко, О. К. (2021)
Chimeric Antigen Receptor T Cells, the Shock of the New*
Morris, A. C. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005153
Sriharan, S., Kay, G., Lee, J. C. Y., Pollock, R. D., & Russomano, T. (2021) · Aerospace Medicine and Human Performance · doi:10.3357/amhp.5937.2021
(2021) · Elsevier eBooks · doi:10.1016/b978-3-437-23841-3.00041-2
Bakhsh, A. A., Safhi, M. A., Alghamdi, A., Alharazi, A., Alshabibi, B., Alobaidi, R., & Alnashri, M. M. (2021) · Research Square · doi:10.21203/rs.3.rs-145019/v1
What's New in Emergencies, Trauma, and Shock – Prehospital Cardiac Arrest in Trauma Victims
Chauhan, V. (2021) · Journal of Emergencies Trauma and Shock · doi:10.4103/jets.jets_162_21
Arianayagam, S. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0006
Baldwin, A. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0013
Errors in the Context of the Perioperative Administration of Medications
Merry, A., & Wahr, J. A. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108151702.007
Pennoyer, A., & Patel, S. (2017) · The American Pharmacists Association eBooks · doi:10.21019/pharmacotherapyfirst.cardiac-arrest_overview
Buckley, S. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0003
Baldwin, A. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780192888501.003.0014
Goumalatsou, C. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0002
Epinephrine for out-of-hospital cardiac arrest has neurological risk
(2018) · Reactions Weekly · doi:10.1007/s40278-018-49843-8
Denniston, A. K., & Mathewson, P. A. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0004
Hjelde, N. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0011
Graham, B. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.003.0009
Rianimazione cardiopolmonare in ambito ospedaliero
Debord, S., Peguet, O., Carry, P.-Y., & Gueugniaud, P.-Y. (2022) · EMC - Anestesia-Rianimazione · doi:10.1016/s1283-0771(22)46426-7
Inotropes, pressors, and vasodilators
Price, S., & Uddin, S. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780198766223.003.0044
Pharmacotherapy during cardiopulmonary resuscitation
Krüger, A. (2021) · Intervenční a akutní kardiologie · doi:10.36290/kar.2021.020
Paramedic Practice in England with Adrenaline Following Return Of Spontaneous Circulation (ROSC)Preprint
Webb, L. (2022) · Research Square · doi:10.21203/rs.3.rs-1823325/v1
Research progress of brain injury after cardiopulmonary resuscitation
Yao, P., Ma, W., Wang, Z., Songling, T. A. N. G., Jian, M., Zhou, T., XIANG, X., Zhou, F., Gan, L., He, Y., et al. (2022) · Scientia Sinica Vitae · doi:10.1360/ssv-2022-0158
Nikolov, K., Ahl, E., Wagner, H., & Härdig, B. M. (2022) · Research Square · doi:10.21203/rs.3.rs-1685072/v1
AIC-Wissenschaftspreis 2022: 1. Platz
Putzer, G. (2022) · Anästhesie Nachrichten · doi:10.1007/s44179-022-00110-1
Zeng, R., Lai, F., Huang, M., Zhu, D., Chen, B., Tao, L., Huang, W., Lai, C., & Ding, B. (2023) · Pilot and Feasibility Studies · doi:10.1186/s40814-023-01239-9
Out-of-Hospital Cardiac Arrest—Achilles’ Heel in Cardiovascular Medicine
Adler, C., Heyne, S., Meertens, M. M., Macherey‐Meyer, S., & Baldus, S. E. (2023) · Springer eBooks · doi:10.1007/978-3-031-20260-5_27
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0004
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0010
JABC, & JML (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0008
Baldwin, A. (2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0007
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0002
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0003
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780198827191.002.0011
Reference intervals—biochemistry
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780192888501.002.0012
Reference intervals—haematology
(2020) · Oxford University Press eBooks · doi:10.1093/med/9780192888501.002.0013
Epinephrine and Outcomes Following Cardiac Arrest
Chacko, J., Pawar, S., Seppelt, I., & Brar, G. (2023) · Springer eBooks · doi:10.1007/978-981-19-9940-6_23
Fatores prognósticos da ressuscitação cardiopulmonar pediátrica no hospital
Sakano, T. M. S. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2022.tde-26042023-125225
use of adrenaline in cardiac arrest - impact on survival to discharge from the hospital
Zimnicki, P., Lato, M., Iberszer, K., Litwiniuk, M., Zaniuk, M., HURKAŁA, K., ANTONIK, D., Denys, B., Góra, K., & Zdziennicki, W. (2023) · Journal of Education Health and Sport · doi:10.12775/jehs.2023.30.01.006
Redazione, R. (2020) · Scenario - Il Nursing nella sopravvivenza · doi:10.4081/scenario.2019.419
Härdig, B. M. (2023) · International Journal of Clinical Cardiology and Cardiovascular Interventions · doi:10.61148/2836-2837/ijccci/010
Extracorporeal cardiopulmonary resuscitation
Teixeira, J. P., Larson, L. M., Schmid, K. M., Azevedo, K., & Kraai, E. P. (2023) · International Anesthesiology Clinics · doi:10.1097/aia.0000000000000415
KORHN risk score for early neuroprognostication in cardiac arrest patientsPreprint
Choi, W. J., Lee, J. H., Jang, T. C., Oh, S. H., & Im, J. Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1485762/v1
Rex, S., & Erber, K. (2023) · Springer Reference Medizin · doi:10.1007/978-3-642-54675-4_40-2
Zhang, B., McCracken, B. M., Colmenero, C. I., Leander, D. C., Greer, N. L., Cranford, J. A., Hsu, C. H., Tiba, M. H., Neumar, R. W., & Greineder, C. F. (2023) · Resuscitation Plus · doi:10.1016/j.resplu.2023.100477
Withdrawal of life sustaining treatment after resuscitation from cardiac arrest: Quo Vadis?
Goren, E., Hoering, A., & Nichol, G. (2023) · Resuscitation · doi:10.1016/j.resuscitation.2023.109988
EMPODERANDO HERÓIS ANÔNIMOS: RELATO DE EXPERIÊNCIA SOBRE O DIA NACIONAL DA REANIMAÇÃO CARDIOPULMONAR
Lucena, Ê. A. C., Bulhão, M. P., de Castro, M. D. V. M., de Oliveira, C. Q., & Uchôa, Y. C. (2023) · Jornada de Urgência e Emergência LAUEC · doi:10.29327/1318927.4-18
Epinephrine and brain perfusion during cardiac arrest: every minute counts
Segond, N., Jaeger, D., & Debaty, G. P. (2023) · Resuscitation · doi:10.1016/j.resuscitation.2023.110006
Hoehne, S. N., Iannucci, C., Murthy, V. D., Dutil, G. F., & Maiolini, A. (2023) · Journal of Veterinary Emergency and Critical Care · doi:10.1111/vec.13347
Salvadori, F. A. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2023.tde-21112023-131010
Seiner, J., Strýček, M., Polášek, R., & Roubíček, T. (2023) · Intervenční a akutní kardiologie · doi:10.36290/kar.2023.031
Geographical Distribution of COVID-19 Infection Across Saudi Arabia
Aldossari, H. M. (2024) · Journal of Anesthesia & Intensive Care Medicine · doi:10.19080/jaicm.2023.12.555862
Breglia, A., Pettenella, P., Cervino, L., Fossa, C., & Zanatta, M. (2024) · Emergency Care and Medicine · doi:10.3390/ecm1010007
The Pharmacologic Management of Cardiac Arrest
Singh, A., Heeney, M. E., & Montgomery, M. E. (2024) · Cardiology Clinics · doi:10.1016/j.ccl.2024.02.012
Koga, Y., Fujita, M., Yagi, T., Todani, M., Nakahara, T., Kaneda, K., & Tsuruta, R. (2024) · Cureus · doi:10.7759/cureus.59926
Palatinus, H. N., Johnson, M. A., & Youngquist, S. T. (2024) · Resuscitation · doi:10.1016/j.resuscitation.2024.110316
Sıvı ve Elektrolit Bozuklukları
DEMIRTAKAN, T. (2024) · doi:10.5152/2311
Akdeniz, Y. S. (2024) · doi:10.5152/2313
Erişkin İleri Kardiyak Yaşam Desteği
BIBEROĞLU, S. (2024) · doi:10.5152/2303
Aman, G. (2024) · doi:10.5152/2307
ÖZKAN, S. (2024) · doi:10.5152/2305
Batıkan, E. (2024) · doi:10.5152/2315
Non-İnvaziv ve İnvaziv Mekanik Ventilasyon
İPEKCI, A. (2024) · doi:10.5152/2302
Pediatrik İleri Kardiyak Yaşam Desteği
ÖZKAN, S. (2024) · doi:10.5152/2304
Akdeniz, Y. S., & Çirkin, Y. (2024) · doi:10.5152/2310
Orhan, Ç. (2024) · doi:10.5152/2306
Kırmızı Alan: Acilde Kritik Vakalar I
Ikızcelı, İ., Özkan, S., İpekci, A., Kanbakan, A., Orhan, Ç., Batıkan, E., Çakmak, F., Aman, G., Yılmaz, N., Biberoğlu, S., et al. (2024) · doi:10.5152/2300
İPEKCI, A. (2024) · doi:10.5152/2312
Akdeniz, Y. S. (2024) · doi:10.5152/2316
Efficacy of radial artery cannulation in treatment of cardiac arrest: A case report
Li, J., Ji, H., & Xu, J. (2024) · Medicine · doi:10.1097/md.0000000000039149
Rex, S., & Erber, K. (2024) · Springer Reference Medizin · doi:10.1007/978-3-662-68699-7_40
Garcia, S. I., & Wieruszewski, P. M. (2024) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2024.08.024
If at First You Don’t Get ROSC: Dose, Dose Again…*
Pinto, V. L., & Dezfulian, C. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006364
Strategies for early adrenaline administration using a kitchen timer for time management
Nakamura, N., Nakagawa, K., Ueta, H., Hata, K., & Tanaka, H. (2024) · Journal of EMS Medicine · doi:10.35616/jemsm.2024.00101
Cardiopulmonary resuscitation and post-resuscitation care
O'Connor, M. C., & Cattlin, C. S. (2024) · Anaesthesia & intensive care medicine · doi:10.1016/j.mpaic.2024.08.011
McGraw, M., Chandra, K., Mekwan, J., Fraser, J. M., McDougall, P., Pishe, T., & Atkinson, P. (2024) · Research Square · doi:10.21203/rs.3.rs-5663050/v1
Cheskes, S. (2025) · Annals of Internal Medicine · doi:10.7326/annals-25-00159-jc
Cheskes, S. (2025) · Annals of Internal Medicine · doi:10.7326/annals-25-00160-jc
Tsoungani, G., & Nour, S. (2025) · Archives of Academic Emergency Medicine · doi:10.22037/aaemj.v13i1.2447
Impact of the COVID-19 Pandemic on Out-of-Hospital Cardiac Arrests Occurring in the Workplace
Tanaka, Y., Tanaka, K., Ushimoto, T., & Inaba, H. (2025) · Cureus · doi:10.7759/cureus.80168
Lee, J., Park, J. H., Jung, E., Ryu, H. H., Song, K. J., & Shin, S. D. (2025) · Prehospital Emergency Care · doi:10.1080/10903127.2025.2489036
Giannopoulou, E., Latsios, G., Tsilivarakis, D., Sanidas, E. A., Toutouzas, K. P., Tsioufis, K. P., & Kosmopoulou, S. (2025) · Hellenic Journal of Cardiology · doi:10.1016/j.hjc.2025.05.003
How should shock-resistant ventricular fibrillation best be analyzed and handled?
Nordseth, T. (2025) · Resuscitation · doi:10.1016/j.resuscitation.2025.110643
Predictors of response to peri-arrest bolus epinephrine in children
Sorcher, J. L., Kundun, H., Mehta, S. M., Grossestreuer, A. V., Donnino, M. W., Kleinman, M. E., & Ross, C. E. (2025) · Resuscitation Plus · doi:10.1016/j.resplu.2025.101020
Metadata
- Authors
- Perkins, G. D., Ji, C., Deakin, C. D., Quinn, T., Nolan, J. P., Scomparin, C., Regan, S., Long, J., Slowther, A., Pocock, H., Black, J. J. M., Moore, F., Fothergill, R. T., Rees, N., O’Shea, L., Docherty, M., Gunson, I., Han, K., Charlton, K., Finn, J., Petrou, S., Stallard, N., Gates, S., & Lall, R.
- Affiliations
- University of Warwick (GB)
- National Institute for Health and Care Research (GB)
- St George's, University of London (GB)
- Royal United Hospital (GB)
- North East Ambulance Service NHS Foundation Trust (GB)
- Curtin University (AU)
- ORCID
- Perkins, Gavin D.
- Ji, Chen
- Deakin, Charles D.
- Quinn, Tom
- Nolan, Jerry P.
- Scomparin, Charlotte
- Regan, Scott
- Long, John
- Slowther, Anne
- Pocock, Helen
- Black, John J.M.
- Moore, Fionna
- Fothergill, Rachael T.
- Rees, Nigel
- O’Shea, Lyndsey
- Docherty, Mark
- Gunson, Imogen
- Han, Kyee
- Charlton, Karl
- Finn, Judith
- Petrou, Stavros
- Stallard, Nigel
- Gates, Simon
- Lall, Ranjit
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2018-08-23
- Volume
- 379
- Issue
- 8
- Pages
- 711-721
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2883159984
- Cited by
- 794
- References
- 35
- Citations by year
- 2026: 59 · 2025: 88 · 2024: 101 · 2023: 87 · 2022: 74 · 2021: 105 · 2020: 150 · 2019: 102 · 2018: 27
- FWCI
- 117.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- Monash University Research Portal (Monash University) (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Research Repository (Kingston University London) (acceptedVersion)
- Warwick Research Archive Portal (University of Warwick) (acceptedVersion, other-oa)
- eSpace (Curtin University) (submittedVersion)
- amber - ambulance research repository (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion, other-oa)
- Explore Bristol Research (submittedVersion)
- Funders
- Health Technology Assessment Programme (12/127/126)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- out-of-hospital cardiac arrest, epinephrine, cardiopulmonary resuscitation, 30-day survival, neurological outcome, modified Rankin Scale, paramedics, ambulance services, United Kingdom National Health Service, resuscitation guidelines
- MeSH terms
- Aged, Combined Modality Therapy, Double-Blind Method, Electric Countershock, Emergency Medical Services, Epinephrine, Female, United Kingdom, Humans, Male, Middle Aged, Nervous System Diseases, Sympathomimetics, Survival Rate, Cardiopulmonary Resuscitation, Hospital Mortality, Out-of-Hospital Cardiac Arrest, Time-to-Treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
