Cited by 171Suicide and Self-Harm StudiesTreatment of Major DepressionMental Health Treatment and Access

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Antidepressants' Black-Box Warning — 10 Years Later

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Friedman, Richard A.·2014·New England Journal of Medicine

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Abstract

In 2004, the FDA issued a black-box warning linking antidepressants to an increased risk of suicidal thinking, feeling, and behavior in young people. But some worrisome trends suggest that the warning may inadvertently discourage appropriate treatment of depression.

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Authors: Friedman, R. A.
Affiliations: Cornell University (US)
Corresponding author: Friedman, Richard A.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2014-10-30
Volume: 371
Issue: 18
Pages: 1666-1668
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmp1408480
OpenAlex: W2006985105
Cited by: 171
References: 5
Citations by year: 2026: 7 · 2025: 11 · 2024: 19 · 2023: 11 · 2022: 14 · 2021: 9 · 2020: 15 · 2019: 13 · 2018: 34 · 2017: 14 · 2016: 11 · 2015: 11 · 2014: 1
FWCI: 14.55
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: antidepressants, black box warning, suicide risk, FDA drug labeling, treatment underuse, depression treatment
MeSH terms: Suicide Prevention, Adolescent, Adult, Aged, Antidepressive Agents, Child, Depressive Disorder, Drug Labeling, Drug Utilization, Humans, Risk Factors, Suicide, United States, United States Food and Drug Administration, Government Regulation

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Antidepressants' Black-Box Warning — 10 Years Later

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