The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Insulin Analogues
Abstract
In the 1990s, the value of glycemic control in the management of diabetes became incontrovertible. The interest in producing insulin formulations that are safer than previous formulations and that more closely duplicate the basal and mealtime components of endogenous insulin secretion has yielded insulin analogues with action profiles that afford more flexible treatment regimens and a lower risk of hypoglycemia. This article examines the use of these newer insulins in clinical practice.
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“Specifically, improved glycemic control in the DCCT was associated with a 2–6 fold increase in severe hypoglycemia in intensive as compared to conventionally treated subjects101.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [101]
Citations
Cites
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Outpatient Insulin Therapy in Type 1 and Type 2 Diabetes Mellitus: Scientific Review
DeWitt, D. E., & Hirsch, I. B. (2003) · JAMA · doi:10.1001/jama.289.17.2254 · Cited by 502
Self-citationDiminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
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Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277
Epidemiology of type 1 diabetes
Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.011 · Cited by 1,092
Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes
Bergenstal, R. M., Tamborlane, W. V., Ahmann, A., Buse, J. B., Dailey, G., Davis, S. N., Joyce, C., Peoples, T., Perkins, B. A., Welsh, J. B., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1002853 · Cited by 894
Metadata
- Authors
- Hirsch, I. B.
- Affiliations
- University of Washington (US)
- Corresponding author
- Hirsch, Irl B.
- ORCID
- Hirsch, Irl B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-01-13
- Volume
- 352
- Issue
- 2
- Pages
- 174-183
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4242554702
- Cited by
- 667
- References
- 62
- Citations by year
- 2026: 13 · 2025: 8 · 2024: 14 · 2023: 11 · 2022: 23 · 2021: 16 · 2020: 26 · 2019: 19 · 2018: 31 · 2017: 29 · 2016: 36 · 2015: 36 · 2014: 27 · 2013: 39 · 2012: 46
- FWCI
- 5.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- insulin analogues, glycemic control, diabetes mellitus, hypoglycemia risk, insulin formulations
- MeSH terms
- Insulin Glargine, Child, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Drug Administration Schedule, Female, Humans, Hypoglycemic Agents, Insulin, Pregnancy, Blood Glucose Self-Monitoring, Insulin, Long-Acting, Insulin Aspart, Insulin Lispro
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