Insulin Analogues

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

(1998) · The Lancet · doi:10.1016/s0140-6736(98)07019-6 · Cited by 20,023

Untitled work

Riddle (2003) · doi:10.2337/diacare.26.11.3080 · Cited by 1,479

Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.

Lepore, M., Pampanelli, S., Fanelli, C., Porcellati, F., Bartocci, L., Di Vincenzo, A., Cordoni, C., Costa, E., Brunetti, P., & Bolli, G. B. (2000) · Diabetes · doi:10.2337/diabetes.49.12.2142 · Cited by 818

Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells

Quagliaro, L., Piconi, L., Assaloni, R., Martinelli, L., Motz, E., & Ceriello, A. (2003) · Diabetes · doi:10.2337/diabetes.52.11.2795 · Cited by 772

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use

Kurtzhals, P., Schäffer, L., Sørensen, A., Kristensen, C., Jonassen, I., Schmid, C., & Trüb, T. (2000) · Diabetes · doi:10.2337/diabetes.49.6.999 · Cited by 739

Standards of Medical Care in Diabetes

(2004) · Diabetes Care · doi:10.2337/diacare.27.2007.s15 · Cited by 688

Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes. HOE 901/3002 Study Group.

Yki‐Järvinen, H., Dressler, A., Ziemen, M., & HOE 901/300s Study Group (2000) · Diabetes Care · doi:10.2337/diacare.23.8.1130 · Cited by 573

Outpatient Insulin Therapy in Type 1 and Type 2 Diabetes Mellitus: Scientific Review

DeWitt, D. E., & Hirsch, I. B. (2003) · JAMA · doi:10.1001/jama.289.17.2254 · Cited by 502

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

Ward, W. K., Bolgiano, D. C., McKnight, B., Halter, J. B., & Porte, D. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111542 · Cited by 483

Protein Therapeutics: A Summary and Pharmacological Classification

Leader, B., Baca, Q. J., & Golan, D. E. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2399 · Cited by 2,161

Trends in peptide drug discovery

Muttenthaler, M., King, G. F., Adams, D. J., & Alewood, P. F. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-00135-8 · Cited by 2,074

Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline

Cryer, P. E., Axelrod, L., Grossman, A. B., Heller, S. R., Montori, V. M., Seaquist, E. R., & Service, F. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1410 · Cited by 1,277

Epidemiology of type 1 diabetes

Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.011 · Cited by 1,092

Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes

Bergenstal, R. M., Tamborlane, W. V., Ahmann, A., Buse, J. B., Dailey, G., Davis, S. N., Joyce, C., Peoples, T., Perkins, B. A., Welsh, J. B., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1002853 · Cited by 894

Consensus Statement By The American Association Of Clinical Endocrinologists And American College Of Endocrinology On The Comprehensive Type 2 Diabetes Management Algorithm – 2016 EXECUTIVE SUMMARY

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S. E., DeFronzo, R. A., EINHORN, D. F., Fonseca, V. A., et al. (2016) · Endocrine Practice · doi:10.4158/ep151126.cs · Cited by 879

Severe hypoglycemia in critically ill patients: risk factors and outcomes

Krinsley, J. S., & Grover, A. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000282073.98414.4b · Cited by 671

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm - 2020 executive summary

Garber, A. J., Handelsman, Y., Grunberger, G., Einhorn, D., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bush, M. A., DeFronzo, R. A., Garber, J. R., et al. (2020) · Endocrine Practice · doi:10.4158/cs-2019-0472 · Cited by 598

Diabetes mellitus and periodontal disease

Mealey, B. L., & Ocampo, G. L. (2007) · Periodontology 2000 · doi:10.1111/j.1600-0757.2006.00193.x · Cited by 579

American Association of Clinical Endocrinologists and American College of Endocrinology - clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015

Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G., Zimmerman, R. S., Bailey, T. S., Blonde, L., Bray, G. A., Cohen, A. J., Dagogo-Jack, S., et al. (2015) · Endocrine Practice · doi:10.4158/ep15672.glsuppl · Cited by 559

Rates of Complications and Mortality in Older Patients With Diabetes Mellitus: The Diabetes and Aging Study

Huang, E. S., Laiteerapong, N., Liu, J. Y., John, P. M., Moffet, H. H., & Karter, A. J. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.12956 · Cited by 501

Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2018 Executive Summary

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S. E., DeFronzo, R. A., EINHORN, D. F., Fonseca, V. A., et al. (2018) · Endocrine Practice · doi:10.4158/cs-2017-0153 · Cited by 503

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm – 2017 executive summary

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S., DeFronzo, R. A., Einhorn, D., Fonseca, V. A., et al. (2017) · Endocrine Practice · doi:10.4158/ep161682.cs · Cited by 435

Mechanisms of Hypoglycemia-Associated Autonomic Failure and Its Component Syndromes in Diabetes

Cryer, P. E. (2005) · Diabetes · doi:10.2337/diabetes.54.12.3592 · Cited by 406

Management of Hyperglycemia in the Hospital Setting

Inzucchi, S. E. (2006) · New England Journal of Medicine · doi:10.1056/nejmcp060094 · Cited by 391

Emerging micro- and nanotechnology based synthetic approaches for insulin delivery

Mo, R., Jiang, T., Di, J., Tai, W., & Gu, Z. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60436e · Cited by 389

American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Developing a Diabetes Mellitus Comprehensive Care Plan

Handelsman, Y., Mechanick, J. I., Blonde, L., Grunberger, G., Bloomgarden, Z. T., Bray, G. A., Dagogo-Jack, S., Davidson, J. A., Einhorn, D., Ganda, O., et al. (2011) · Endocrine Practice · doi:10.4158/ep.17.s2.1 · Cited by 513

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm—2019 executive summary.

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S., DeFronzo, R. A., Einhorn, D., Fonseca, V. A., et al. (2019) · Endocrine Practice · doi:10.4158/cs-2018-0535 · Cited by 297

Society for Ambulatory Anesthesia Consensus Statement on Perioperative Blood Glucose Management in Diabetic Patients Undergoing Ambulatory Surgery

Joshi, G. P., Chung, F. F., Vann, M. A., Ahmad, S., Gan, T. J., Goulson, D. T., Merrill, D. G., & Twersky, R. S. (2010) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181f9c288 · Cited by 299

Pursuit of a perfect insulin

Zaykov, A. N., Mayer, J. P., & DiMarchi, R. D. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.36 · Cited by 294

Efficacy and safety of insulin analogues for the management of diabetes mellitus: a meta-analysis

Singh, S. R., Ahmad, F., Lal, A., Yu, C., Bai, Z., & Bennett, H. (2009) · Canadian Medical Association Journal · doi:10.1503/cmaj.081041 · Cited by 241

Towards peakless, reproducible and long‐acting insulins. An assessment of the basal analogues based on isoglycaemic clamp studies

Heise, T., & Pieber, T. R. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2007.00756.x · Cited by 236

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates

Chou, D. H., Webber, M. J., Tang, B. C., Lin, A. B., Thapa, L. S., Deng, D., Truong, J. V., Cortinas, A. B., Langer, R., & Anderson, D. G. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424684112 · Cited by 237

Insulin structure and function

Mayer, J. P., Zhang, F. P. Y., & DiMarchi, R. D. (2007) · Biopolymers · doi:10.1002/bip.20734 · Cited by 248

Gender-specific care of the patient with diabetes: review and recommendations

Legato, M. J., Gelzer, A., Goland, R., Ebner, S. A., Rajan, S., Villagra, V., & Kosowski, M. (2006) · Gender Medicine · doi:10.1016/s1550-8579(06)80202-0 · Cited by 225

Mechanisms of hypoglycemia unawareness and implications in diabetic patients

Martín-Timón, I. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i7.912 · Cited by 204

Hypoglycemia in Type 1 Diabetes Mellitus

Cryer, P. E. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.003 · Cited by 205

A randomized trial of adding insulin glargine vs. avoidance of insulin in people with Type 2 diabetes on either no oral glucose‐lowering agents or submaximal doses of metformin and/or sulphonylureas. The Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study

Gerstein, H. C., Yale, J. ‐., Harris, S. B., Issa, M., Stewart, J. A., & Dempsey, E. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01881.x · Cited by 197

Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: Oral delivery using pH-Responsive nanoparticles vs. subcutaneous injection

Sonaje, K., Lin, K., Wey, S., Lin, C.-K., Yeh, T.-H., Nguyen, H.-N., Hsu, C., Yen, T., Juang, J., & Sung, H. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.05.042 · Cited by 187

Pharmacotherapy of type 2 diabetes: An update

Upadhyay, J., Pοlyzos, S. A., Perakakis, N., Thakkar, B., Paschou, S. Α., Katsiki, N., UNDERWOOD, P. C., Park, K., Seufert, J., Kang, E. S., et al. (2017) · Metabolism · doi:10.1016/j.metabol.2017.08.010 · Cited by 196

Hypoglycemia: Still The Limiting Factor in the Glycemic Management of Diabetes

Cryer, P. E. (2008) · Endocrine Practice · doi:10.4158/ep.14.6.750 · Cited by 184

Insulin therapy for type 2 diabetes.

Swinnen, S. G., Hoekstra, J. B., & DeVries, J. H. (2009) · Diabetes Care · doi:10.2337/dc09-s318 · Cited by 181

Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells

Weinstein, D., Simon, M., Yehezkel, E., Laron, Z., & Werner, H. (2009) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.912 · Cited by 179

A novel approach using functional peptides for efficient intestinal absorption of insulin

Morishita, M., Kamei, N., Ehara, J., Isowa, K., & Takayama, K. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.12.022 · Cited by 166

Hydrogels in Emerging Technologies for Type 1 Diabetes

Fuchs, S., Ernst, A. U., Wang, L., Shariati, K., Wang, X., Liu, Q., & Ma, M. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01062 · Cited by 162

Pharmacotherapy of type 2 diabetes: An update and future directions

DeMarsilis, A. J., Reddy, N., Boutari, C., Filippaios, A., Sternthal, E., Katsiki, N., & Mantzoros, C. S. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155332 · Cited by 173

Immunogenicity to Biologics: Mechanisms, Prediction and Reduction

Sethu, S., Govindappa, K., Alhaidari, M., Pirmohamed, M., Park, K., & Sathish, J. G. (2012) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-012-0189-7 · Cited by 154

Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling

Sciacca, L., Cassarino, M. F., Genua, M., Pandini, G., Moli, R. L., Squatrito, S., & Vigneri, R. (2010) · Diabetologia · doi:10.1007/s00125-010-1760-6 · Cited by 142

Proportion of patients at HbA1c target <7% with eight classes of antidiabetic drugs in type 2 diabetes: systematic review of 218 randomized controlled trials with 78 945 patients

Esposito, K., Chiodini, P., Bellastella, G., Maiorino, M. I., & Giugliano, D. (2012) · Diabetes, Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01512.x · Cited by 136

Clinical Application of Emerging Sensor Technologies in Diabetes Management: Consensus Guidelines for Continuous Glucose Monitoring (CGM)

Hirsch, I. B., Armstrong, D. U., Bergenstal, R. M., Buckingham, B. A., Childs, B. P., Clarke, W. L., Peters, A. L., & Wolpert, H. A. (2008) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2008.0016 · Cited by 135

Insulin Units and Conversion Factors: A Story of Truth, Boots, and Faster Half-Truths

Knopp, J. L., Holder-Pearson, L. R., & Chase, J. G. (2018) · Journal of Diabetes Science and Technology · doi:10.1177/1932296818805074 · Cited by 138

Introducing a simplified approach to insulin therapy in type 2 diabetes: a comparison of two single‐dose regimens of insulin glulisine plus insulin glargine and oral antidiabetic drugs

Lankisch, M., Ferlinz, K., Leahy, J. L., Scherbaum, W. A., & Orals Plus Apidra and LANTUS (OPAL) study group (2008) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2008.00967.x · Cited by 133

The Australasian Diabetes in Pregnancy Society consensus guidelines for the management of type 1 and type 2 diabetes in relation to pregnancy

McElduff, A., Cheung, N. W., McIntyre, D. H., Lagstrom, J., Walters, B. N. J., Oats, J. J. N., Wein, P., Ross, G. P., & Simmons, D. S. (2005) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2005.tb07087.x · Cited by 130

Pharmacological Targeting of Mitochondria in Diabetic Kidney Disease

Cleveland, K. H., & Schnellmann, R. G. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.122.000560 · Cited by 134

Efficacy of Insulin Analogs in Achieving the Hemoglobin A1c Target of <7% in Type 2 Diabetes

Giugliano, D., Maiorino, M. I., Bellastella, G., Chiodini, P., Ceriello, A., & Esposito, K. (2011) · Diabetes Care · doi:10.2337/dc10-1710 · Cited by 127

New Drugs for Type 2 Diabetes Mellitus

Krentz, A. J., Patel, M., & Bailey, C. J. (2008) · Drugs · doi:10.2165/00003495-200868150-00005 · Cited by 122

Diabetes mellitus and other disorders of metabolism

(2009) · Elsevier eBooks · doi:10.1016/b978-0-7020-2993-6.00024-9 · Cited by 121

Exercise and Glycemic Control in Diabetes: Benefits, Challenges, and Adjustments to Pharmacotherapy

Gulve, E. A. (2008) · Physical Therapy · doi:10.2522/ptj.20080114 · Cited by 120

Rapid Pharmacokinetics of Intradermal Insulin Administered Using Microneedles in Type 1 Diabetes Subjects

Gupta, J., Felner, E. I., & Prausnitz, M. R. (2011) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2010.0204 · Cited by 118

A Randomized Clinical Trial of the Effect of Continuous Glucose Monitoring on Nocturnal Hypoglycemia, Daytime Hypoglycemia, Glycemic Variability, and Hypoglycemia Confidence in Persons with Type 1 Diabetes Treated with Multiple Daily Insulin Injections (GOLD-3)

Ólafsdóttir, A. F., Polonsky, W. H., Bolinder, J., Hirsch, I. B., Dahlqvist, S., Wedel, H., Nyström, T., Wijkman, M. O., Schwarcz, E., Hellman, J., et al. (2018) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2017.0363 · Cited by 115

Advances in Peptidomimetics for Next-Generation Therapeutics: Strategies, Modifications, and Applications

Lombardi, L., Genio, V. D., Alberício, F., & Williams, D. R. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00989 · Cited by 130

Insulin therapy in renal disease

Iglesias, P., & Díez, J. J. (2008) · Diabetes, Obesity and Metabolism · doi:10.1111/j.1463-1326.2007.00802.x · Cited by 110

Immune therapy in type 1 diabetes mellitus

Lernmark, Å., & Larsson, H. E. (2013) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.237 · Cited by 109

Lipodystrophy Reactions to Insulin

Radermecker, R. P., rard, G. R. E. P., & Scheen, A. J. (2007) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200708010-00003 · Cited by 107

What's fueling the biotech engine?

Aggarwal, S. (2007) · Nature Biotechnology · doi:10.1038/nbt1007-1097 · Cited by 105

MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview

Diamanti‐Kandarakis, E., Dattilo, M., Μacut, D., Duntas, L. H., Gonos, E. S., Goulis, D. G., Kanaka‐Gantenbein, C., Καπετάνου, Μ., Koukkou, E. G., Lambrinoudaki, I. V., et al. (2017) · European Journal of Endocrinology · doi:10.1530/eje-16-1061 · Cited by 105

Smart approaches to glucose-responsive drug delivery

Webber, M. J., & Anderson, D. G. (2015) · Journal of drug targeting · doi:10.3109/1061186x.2015.1055749 · Cited by 103

Basal insulin analogues in the management of diabetes mellitus: what progress have we made?

Owens, D. R., Matfin, G., & Monnier, L. (2013) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2469 · Cited by 102

Allergy reactions to insulin: effects of continuous subcutaneous insulin infusion and insulin analogues

Radermecker, R. P., & Scheen, A. J. (2007) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.714 · Cited by 100

Continuous Glucose Monitoring and Insulin Informed Advisory System with Automated Titration and Dosing of Insulin Reduces Glucose Variability in Type 1 Diabetes Mellitus

Breton, M. D., Patek, S. D., Lv, D., Schertz, E. M., Robic, J., Pinnata, J., Kollar, L. L., Barnett, C. L., WAKEMAN, C. A., Oliveri, M. C., et al. (2018) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2018.0079 · Cited by 102

15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2026

Bajaj, M. S., McCoy, R. G., Balapattabi, K., Bannuru, R. R., Bellini, N. J., Bennett, A. K., Beverly, E. A., Early, K. B., Brown, F. M., ChallaSivaKanaka, S., et al. (2025) · Diabetes Care · doi:10.2337/dc26-s015 · Cited by 132

Further Exploration of the Relationship Between Insulin Glargine and Incident Cancer

Morden, N. E., Liu, S. K., Smith, J., MacKenzie, T. A., Skinner, J., & Korc, M. (2011) · Diabetes Care · doi:10.2337/dc11-0699 · Cited by 94

Refining basal insulin therapy: what have we learned in the age of analogues?

DeVries, J. H., Nattrass, M., & Pieber, T. R. (2007) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.762 · Cited by 94

Management of Gestational Diabetes: Pharmacologic Treatment Options and Glycemic Control

Langer, O. (2006) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2005.09.007 · Cited by 91

Diabetes in pregnancy: health risks and management

Ali, S. N., & Dornhorst, A. (2011) · Postgraduate Medical Journal · doi:10.1136/pgmj.2010.109157 · Cited by 91

Insulin Use in Elderly Adults: Risk of Hypoglycemia and Strategies for Care

Ligthelm, R. J., Kaiser, M., Vora, J. P., & Yale, J. (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2012.04055.x · Cited by 90

Proinsulin and the Genetics of Diabetes Mellitus

Weiss, M. A. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.r109.009936 · Cited by 91

New advances in type 1 diabetes

Subramanian, S., Khan, F. N., & Hirsch, I. B. (2024) · BMJ · doi:10.1136/bmj-2023-075681 · Cited by 105

Insulin Stacking Versus Therapeutic Accumulation: Understanding the Differences

Heise, T., & Meneghini, L. F. (2014) · Endocrine Practice · doi:10.4158/ep13090.ra · Cited by 87

The role of polysaccharides from natural resources to design oral insulin micro- and nanoparticles intended for the treatment of Diabetes mellitus: A review

Meneguin, A. B., Silvestre, A. L. P., Spósito, L., de Souza, M. P. C., Sábio, R. M., Araújo, V. H. S., Cury, B. S. F., & Chorilli, M. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117504 · Cited by 91

Basal Insulin: Physiology, Pharmacology, and Clinical Implications

Niswender, K. D. (2011) · Postgraduate Medicine · doi:10.3810/pgm.2011.07.2300 · Cited by 91

The Contribution of Malglycemia to Mortality among Allogeneic Hematopoietic Cell Transplant Recipients

Hammer, M. J., Casper, C., Gooley, T. A., O’Donnell, P. V., Boeckh, M., & Hirsch, I. B. (2009) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2008.12.488 · Cited by 86

A Review of Types 1 and 2 Diabetes Mellitus and Their Treatment with Insulin

Salsali, A., & Nathan, M. (2006) · American Journal of Therapeutics · doi:10.1097/00045391-200607000-00012 · Cited by 85

Insulin Therapy in Children and Adolescents with Type 1 Diabetes

Malik, F. S., & Taplin, C. E. (2014) · Pediatric Drugs · doi:10.1007/s40272-014-0064-6 · Cited by 91

Prandial Premixed Insulin Analogue Regimens Versus Basal Insulin Analogue Regimens in the Management of Type 2 Diabetes: An Evidence-Based Comparison

Ilag, L. L., Kerr, L., Malone, J. K., & Tan, M. H. (2007) · Clinical Therapeutics · doi:10.1016/j.clinthera.2007.07.003 · Cited by 84

Canine Diabetes Mellitus

Nelson, R. W. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-4456-5.00006-7 · Cited by 86

Insulin Glulisine Complementing Basal Insulins: A Review of Structure and Activity

Becker, R. H. A. (2007) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2006.0035 · Cited by 82

Toward a Fully Automated Artificial Pancreas System Using a Bioinspired Reinforcement Learning Design: In Silico Validation

Lee, S., Kim, J., Park, S. W., Jin, S., & Park, S. (2020) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2020.3002022 · Cited by 89

Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalities

Monnier, L., & Colette, C. (2006) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70241-0 · Cited by 82

Intradermal Microneedle Delivery of Insulin Lispro Achieves Faster Insulin Absorption and Insulin Action than Subcutaneous Injection

Pettis, R. J., Ginsberg, B. H., Hirsch, L. J., Sutter, D. E., Keith, S., McVey, E., Harvey, N. G., Hompesch, M., Nosek, L., Kapitza, C., et al. (2011) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2010.0184 · Cited by 83

Why is there no generic insulin? Historical origins of a modern problem

Greene, J. A., & Riggs, K. R. (2015) · New England Journal of Medicine · doi:10.1056/nejmms1411398 · Cited by 81

Realistic Expectations and Practical Use of Continuous Glucose Monitoring for the Endocrinologist

Hirsch, I. B. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2625 · Cited by 93

The past, present, and future of basal insulins

Pettus, J., Cavaiola, T. S., Tamborlane, W. V., & Edelman, S. V. (2015) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2763 · Cited by 83

Targeting postprandial hyperglycemia

Rendell, M., & Jovanovič, L. (2006) · Metabolism · doi:10.1016/j.metabol.2006.05.012 · Cited by 80

A Practical Approach to Using Trend Arrows on the Dexcom G5 CGM System to Manage Children and Adolescents With Diabetes

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Pharmacokinetics and linear exposure of AFRESA™ compared with the subcutaneous injection of regular human insulin

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