CoChat
Sign Up
Cited by 811

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Drug-Related Hepatotoxicity

Navarro, Victor J., Senior, John R.·2006·New England Journal of Medicine
DOI 10.1056/nejmra052270
Open this paper in CoChat — free account

Abstract

Given its rarity, drug-related hepatotoxicity may not be seen during the initial clinical trials of a new medication. After approval, when many more patients are exposed, toxic effects that are very infrequent may emerge. This review explains the difficulties in identifying the cause of hepatotoxic effects in such situations and provides clinical guidance with regard to the detection, evaluation, and possible prevention of drug-related hepatotoxicity.

Overview

Integrity signals

Registry

Crossref · 10.1056/nejmra052270

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • DILI is a common adverse drug reaction that can lead to liver failure and even death.

    “Drug-induced liver injury (DILI) is a common adverse drug reaction (ADR), and it can lead to liver failure and even death.[1][2][3]”

    From Incidence and Etiology of Drug-Induced Liver Injury in Mainland China (2019) · cites this paper as [2]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 56

  1. 10.1055/s-2002-30101 · DOI
  2. 10.1053/jhep.2002.34857 · DOI
  3. 10.1002/hep.20703 · DOI
  4. Bohan TP, 2001, Neurology, 41, 1405, 10.1212/WNL.56.10.1405 · DOI
  5. 10.1016/0168-8278(90)90124-A · DOI · Paper page
  6. Rosalski SB, McIntyre N. Biochemical investigations in the management of liver disease. In: Bircher J, Benhamou J-P, McIntyre N, Rizetto M, Rodes J, eds. Oxford handbook of clinical hepatology. 2nd ed. Oxford, England: Oxford University Press, 1999:504.
  7. 10.1002/hep.20800 · DOI · Paper page
  8. 10.1053/j.gastro.2005.05.006 · DOI
  9. 10.1001/jama.281.11.1014 · DOI
  10. 10.1001/jama.271.13.992 · DOI
  11. 10.1086/381446 · DOI
  12. 10.1016/S0140-6736(00)03137-8 · DOI
  13. 10.1073/pnas.84.2.551 · DOI
  14. 10.1016/S0168-8278(97)82329-X · DOI
  15. 10.1038/clpt.1992.135 · DOI
  16. Yun CH, 1993, Drug Metab Dispos, 21, 403
  17. 10.1056/NEJM199810223391707 · DOI
  18. 10.1016/S1471-4914(01)02026-3 · DOI
  19. 10.1055/s-2001-12929 · DOI
  20. 10.1055/s-2002-30100 · DOI
  21. Zimmerman HJ. Hepatotoxicity: the adverse effects of drugs and other chemicals on the liver. 2nd ed. Philadelphia: Lippincott Williams & Wilkins, 1999.
  22. 10.1146/annurev.pa.23.040183.000511 · DOI
  23. 10.1001/jama.272.23.1845 · DOI
  24. 10.1053/j.gastro.2004.03.030 · DOI
  25. 10.1016/S0168-8278(97)80492-8 · DOI
  26. 10.1056/NEJMra020526 · DOI
  27. 10.1053/jhep.2002.32102 · DOI
  28. 10.1124/mol.104.007146 · DOI
  29. 10.3816/CCC.2005.n.018 · DOI
  30. 10.1056/NEJM199908193410802 · DOI
  31. 10.1023/A:1005661516165 · DOI
  32. 10.1056/NEJMra011775 · DOI · Paper page
  33. 10.1053/gast.2003.50032 · DOI
  34. 10.1053/j.gastro.2004.02.015 · DOI · Paper page
  35. 10.1053/jhep.2001.21083 · DOI
  36. 10.1016/0895-4356(93)90101-6 · DOI · Paper page
  37. 10.1016/0895-4356(93)90102-7 · DOI · Paper page
  38. 10.1517/14740338.3.4.329 · DOI
  39. 10.1002/hep.510260319 · DOI · Paper page
  40. 10.1053/jhep.2001.20645 · DOI · Paper page
  41. 10.1080/01926230590522356 · DOI
  42. 10.1016/S0168-8278(97)82330-6 · DOI
  43. 10.1002/hep.1840150212 · DOI
  44. 10.1016/S0002-9149(02)02355-X · DOI
  45. The binomial distribution. In: Rosner B. Fundamentals of biostatistics. Belmont, Calif.: Duxbury Press, 1995:82-5.
  46. 10.1056/NEJM199803263381314 · DOI
  47. 10.1016/S0002-9343(02)01529-2 · DOI
  48. 10.1002/hep.20598 · DOI · Paper page
  49. 10.1001/jama.269.21.2765 · DOI
  50. 10.1016/0140-6736(93)90895-N · DOI
  51. Vandenbroucke JP, 2001, Ann Intern Med, 134, 330, 10.7326/0003-4819-134-4-200102200-00017 · DOI
  52. 10.1007/s002280100265 · DOI
  53. 10.1056/NEJMp038145 · DOI
  54. 10.1056/NEJMra020021 · DOI
  55. 10.1002/hep.20948 · DOI
  56. Hoofnagle JH, 2004, Hepatology, 40, 773, 10.1002/hep.20445 · DOI

Cited by

Sorted by citations

Metadata

Authors
Navarro, V. J., & Senior, J. R.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
2006-02-16
Volume
354
Issue
7
Pages
731-739
ISSN
  • 0028-4793
  • 1533-4406
DOI
10.1056/nejmra052270
Cited by
811
References
2
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review