Cited by 2,522Hematopoietic Stem Cell TransplantationTransplantation: Methods and OutcomesMesenchymal stem cell research

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Hematopoietic Stem-Cell Transplantation

Copelan, Edward A.·2006·New England Journal of Medicine

DOI 10.1056/nejmra052638

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Abstract

Hematopoietic stem-cell transplantation, which is used to treat both malignant and nonmalignant conditions, was first conceived more than 50 years ago, but problems associated with transplanting a nonsolid organ and modulating the immune response had to be solved before the procedure could be used clinically. This review summarizes background information about hematopoietic stem-cell transplantation and discusses the current role of the procedure.

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Authors: Copelan, E. A.
Affiliations: The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
Corresponding author: Copelan, Edward A.
ORCID: Copelan, Edward A.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2006-04-27
Volume: 354
Issue: 17
Pages: 1813-1826
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra052638
OpenAlex: W2160666689
Cited by: 2,522
References: 102
Citations by year: 2026: 89 · 2025: 99 · 2024: 121 · 2023: 143 · 2022: 163 · 2021: 149 · 2020: 128 · 2019: 126 · 2018: 128 · 2017: 161 · 2016: 123 · 2015: 162 · 2014: 142 · 2013: 142 · 2012: 120
FWCI: 10.56
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
DigitalGeorgetown (Georgetown University Library) (submittedVersion)
Topics: Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Mesenchymal stem cell research
Keywords: hematopoietic stem cell transplantation, hematopoietic stem cells, immunomodulation, history of transplantation
MeSH terms: Graft vs Host Disease, Humans, Major Histocompatibility Complex, Transplantation Immunology, Transplantation, Autologous, Transplantation, Homologous, Hematopoietic Stem Cell Transplantation, Transplantation Conditioning, Cord Blood Stem Cell Transplantation

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