Cited by 1,597Nanoplatforms for cancer theranosticsAdvances in Oncology and RadiotherapyNanoparticle-Based Drug Delivery

New approaches and procedures for cancer treatment: Current perspectives

Open access
Debela, Dejene Tolossa, Muzazu, Seke GY, Heraro, Kidist Digamo, Ndalama, Maureen Tayamika, Mesele, Betelhiem Woldemedhin, Haile, Dagimawi Chilot, Kitui, Sophia Khalayi, Manyazewal, Tsegahun·2021·SAGE Open Medicine

Abstract

Cancer is a global health problem responsible for one in six deaths worldwide. Treating cancer has been a highly complex process. Conventional treatment approaches, such as surgery, chemotherapy, and radiotherapy, have been in use, while significant advances are being made in recent times, including stem cell therapy, targeted therapy, ablation therapy, nanoparticles, natural antioxidants, radionics, chemodynamic therapy, sonodynamic therapy, and ferroptosis-based therapy. Current methods in oncology focus on the development of safe and efficient cancer nanomedicines. Stem cell therapy has brought promising efficacy in regenerating and repairing diseased or damaged tissues by targeting both primary and metastatic cancer foci, and nanoparticles brought new diagnostic and therapeutic options. Targeted therapy possessed breakthrough potential inhibiting the growth and spread of specific cancer cells, causing less damage to healthy cells. Ablation therapy has emerged as a minimally invasive procedure that burns or freezes cancers without the need for open surgery. Natural antioxidants demonstrated potential tracking down free radicals and neutralizing their harmful effects thereby treating or preventing cancer. Several new technologies are currently under research in clinical trials, and some of them have already been approved. This review presented an update on recent advances and breakthroughs in cancer therapies.

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Crossref · 10.1177/20503121211034366

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83 of 83 references verified0 citation errors · 0 not checkable

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  • When people cannot change a situation, they accept and tolerate it and regulate emotions, especially the force from action tendencies toward immediate avoidance or weakening of the experience, and do not suffer from performance breakdown.

    “when they cannot change the situation, accept and tolerate it and regulate emotions, especially the force resulting from action tendencies in the direction of immediate avoidance or weakening of the experience, and do not suffer from performance breakdown(8).”

    From Effectiveness of Mindfulness Training in Emotion Regulation and Distress Tolerance among Breast Cancer Patients (2024) · cites this paper as [8]

    The Conventional cancer therapies and Advanced and innovative cancer therapies sections discuss treatments and drug resistance, not how people respond when they cannot change a situation. Searches for acceptance, emotion regulation, avoidance, and performance breakdown found no passage addressing the claim. The indexed passages provide no page numbers. (LLM, conf=0.77)

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  • Generally, a person is expected to increase distress tolerance by training in mindfulness-based cognitive therapy.

    “Generally, a person is expected to increase a meta-emotional structure called distress tolerance by training in mindfulness-based cognitive therapy.”

    From Effectiveness of Mindfulness Training in Emotion Regulation and Distress Tolerance among Breast Cancer Patients (2024) · cites this paper as [8]

    The Abstract and the sections on conventional and targeted cancer therapies discuss cancer treatments, not mindfulness-based cognitive therapy or distress tolerance (page numbers unavailable). Searches for those terms and for psychological interventions found no passage addressing the claim. (LLM, conf=0.78)

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Research works printed but not linked: 4

  1. [7]Abbas Z Rehman S. An overview of cancer treatment modalities. Neoplasm 2018; 1: 139– 157.
  2. [14]Mondal J Panigrahi AK Khuda-Bukhsh AR. Conventional chemotherapy: problems and scope for combined therapies with certain herbal products and dietary supplements. Austin J Mol Cell Biol 2014; 1: 10.
  3. [38]Yadav P. Targeted cancer therapy; researchers reflection. Int Peer-Rev J 2017; 1: 11– 17.
  4. [54]Cabuy E. Thermal ablation in cancer treatment. Reliab Cancer Ther 2012; 2: 1– 68.

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Authors
Debela, D. T., Muzazu, S. G., Heraro, K. D., Ndalama, M. T., Mesele, B. W., Haile, D. C., Kitui, S. K., & Manyazewal, T.
Affiliations
  • Addis Ababa University (ET)
  • Centre for Infectious Disease Research in Zambia (ZM)
  • Wachemo University (ET)
  • Center for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Corresponding author
Debela, Dejene Tolossa
Venue
SAGE Open Medicine
Published
2021-01
Volume
9
Pages
20503121211034366-20503121211034366
ISSN
2050-3121 (ISSN-L)
OpenAlex
W3190191592
Cited by
1,597
References
83
Citations by year
2026: 250 · 2025: 487 · 2024: 580 · 2023: 234 · 2022: 46
FWCI
18.14
Type
journal article
Language
en
Open access
Locations
  • SAGE Open Medicine (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advances in Oncology and Radiotherapy
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords
cancer therapy, stem cell therapy, targeted therapy, ablation therapy, cancer nanomedicine, nanoparticles, natural antioxidants, radionics, chemodynamic therapy, sonodynamic therapy, minimally invasive cancer therapy, free radicals

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