The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The Primary Outcome Fails — What Next?
Open accessAbstract
When the primary outcome of a clinical trial fails to reach its prespecified end point, can any clinically meaningful information still be derived from it? This review article addresses that question.
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Cites
High-Dose Atorvastatin after Stroke or Transient Ischemic Attack
The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators (2006) · New England Journal of Medicine · doi:10.1056/nejmoa061894 · Cited by 2,887
Spironolactone for heart failure with preserved ejection fraction
Pitt, B., Pfeffer, M. A., Assmann, S. F., Boineau, R., Anand, I. S., Claggett, B., Clausell, N., Desai, A. S., Diaz, R., Fleg, J. L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1313731 · Cited by 2,809
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A Controlled Trial of Renal Denervation for Resistant Hypertension
Bhatt, D. L., Kandzari, D. E., O'Neill, W. W., D'Agostino, R., Flack, J. M., Katzen, B. T., Leon, M. B., Liu, M., Mauri, L., Negoita, M., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402670 · Cited by 2,186
Long-term use of ticagrelor in patients with prior myocardial infarction
Bonaca, M. P., Bhatt, D. L., Cohen, M., Steg, P. G., Storey, R. F., Jensen, E. C., Magnani, G., Bansilal, S., Fish, M. P., Im, K., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1500857 · Cited by 1,999
A Randomized Trial of Therapies for Type 2 Diabetes and Coronary Artery Disease
(2009) · New England Journal of Medicine · doi:10.1056/nejmoa0805796 · Cited by 1,939
Intention-to-treat concept: A review
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Statistics in Medicine — Reporting of Subgroup Analyses in Clinical Trials
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Cited by
Delayed versus Immediate Cord Clamping in Preterm Infants
Tarnow-Mordi, W., Morris, J., Kirby, A., Robledo, K., Askie, L., Brown, R., Evans, N., Finlayson, S., Fogarty, M., Gebski, V., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1711281 · Cited by 308
Brocklehurst, P., Field, D., Greene, K., Juszczak, E., Keith, R., Kenyon, S., Linsell, L., Mabey, C., Newburn, M., Plachcinski, R., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30568-8 · Cited by 207
Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations
Smith, S. M., Dworkin, R. H., Turk, D. C., McDermott, M. P., Eccleston, C., Farrar, J. T., Rowbotham, M. C., Bhagwagar, Z., Burke, L. B., Cowan, P., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000001952 · Cited by 194
Yamasue, H., Okada, T., Munesue, T., Kuroda, M., Fujioka, T., Uno, Y., Matsumoto, K., Kuwabara, H., Mori, D., Okamoto, Y., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-018-0097-2 · Cited by 185
Maguire, A., Clarkson, J. E., Douglas, G. V., Ryan, V., Homer, T., Marshman, Z., McColl, E., Wilson, N., Vale, L., Robertson, M., et al. (2020) · Health Technology Assessment · doi:10.3310/hta24010 · Cited by 55
Metadata
- Authors
- Pocock, S. J., & Stone, G. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-09
- Volume
- 375
- Issue
- 9
- Pages
- 861-870
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2516880594
- Cited by
- 274
- References
- 12
- FWCI
- 37.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Pocock, S. J., & Stone, G. W. (2016). The Primary Outcome Fails — What Next? New England Journal of Medicine. https://doi.org/10.1056/nejmra1510064
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
