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Evaluation of iron-cobalt/ferrite core-shell nanoparticles for cancer thermotherapy
Abstract
Magnetic nanoparticles (MNPs) offer promise for local hyperthermia or thermoablative cancer therapy. Magnetic hyperthermia uses MNPs to heat cancerous regions in an rf field. Metallic MNPs have larger magnetic moments than iron oxides, allowing similar heating at lower concentrations. By tuning the magnetic anisotropy in alloys, the heating rate at a particular particle size can be optimized. Fe–Co core-shell MNPs have protective CoFe2O4 shell which prevents oxidation. The oxide coating also aids in functionalization and improves biocompatibility of the MNPs. We predict the specific loss power (SLP) for FeCo (SLP ∼450W∕g) at biocompatible fields to be significantly larger in comparision to oxide materials. The anisotropy of Fe-Co MNPs may be tuned by composition and/or shape variation to achieve the maximum SLP at a desired particle size.
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Cited by
Exchange-coupled magnetic nanoparticles for efficient heat induction
Lee, J.-H., Jang, J.-T., Choi, J.-S., Moon, S. H., Noh, S.-H., Kim, J.-W., Kim, J.-G., Kim, I.-S., Park, K. I., & Cheon, J. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.95 · Cited by 1,364
Guardia, P., Di Corato, R., Lartigue, L., Wilhelm, C., Espinosa, A., Garcia-Hernandez, M., Gazeau, F., Manna, L., & Pellegrino, T. (2012) · ACS Nano · doi:10.1021/nn2048137 · Cited by 752
Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy
Liu, X., Zhang, Y., Wang, Y., Zhu, W., Li, G., Ma, X., Zhang, Y., Chen, S., Tiwari, S., Shi, K., et al. (2020) · Theranostics · doi:10.7150/thno.40805 · Cited by 719
Magnetic nanoparticle-based therapeutic agents for thermo-chemotherapy treatment of cancer
Hervault, A., & Thanh, N. T. K. (2014) · Nanoscale · doi:10.1039/c4nr03482a · Cited by 585
Figuerola, A., Di Corato, R., Manna, L., & Pellegrino, T. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2009.12.012 · Cited by 480
Metadata
- Authors
- Habib, A. H., Ondeck, C. L., Chaudhary, P., Bockstaller, M. R., & McHenry, M. E.
- Venue
- Journal of Applied Physics
- Publisher
- AIP Publishing
- Published
- 2008-02-07
- Volume
- 103
- Issue
- 7
- ISSN
- 0021-8979 (ISSN-L)
- 1089-7550
- OpenAlex
- W2061715327
- Cited by
- 263
- References
- 0
- FWCI
- 8.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Habib, A. H., Ondeck, C. L., Chaudhary, P., Bockstaller, M. R., & McHenry, M. E. (2008). Evaluation of iron-cobalt/ferrite core-shell nanoparticles for cancer thermotherapy. Journal of Applied Physics. https://doi.org/10.1063/1.2830975
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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