Cited by 115Allergic Rhinitis and SensitizationAsthma and respiratory diseasesNasal Surgery and Airway Studies

A questionnaire to measure quality of life in adults with nocturnal allergic rhinoconjunctivitis

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Juniper, Elizabeth F., Rohrbaugh, Thomas, Meltzer, Eli O.·2003·Journal of Allergy and Clinical Immunology

Abstract

Background Many patients with rhinoconjunctivitis experience symptoms at night and these interfere with getting a good night's sleep.Objective The aim of this study was to develop the Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) to measure the functional problems that are most troublesome to patients with nocturnal allergic rhinoconjunctivitis (NAR).Methods After generating a list of 256 potentially important items, 132 patients with NAR identified the items that were most troublesome. The top scoring 16 items are included in the NRQLQ in four domains (sleep problems, symptoms during sleep time, symptoms on waking and practical problems). The NRQLQ asks patients to recall their experiences during the previous week and score each item on a 7-point scale.Results One hundred and six patients with NAR participated in a 3 week validation study. This showed the NRQLQ to have good reliability (ICC = 0.87) and responsiveness (responsiveness index = 0.93). For both cross-sectional and longitudinal construct validity correlations between the NRQLQ and other measures of health status were close to a priori predictions.Conclusions The NRQLQ has strong evaluative and discriminative measurement properties and can be used with confidence in both clinical practice and clinical trials to measure the functional impairments that are most troublesome to patients with nocturnal allergic rhinoconjunctivitis.

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Crossref · 10.1067/mai.2003.137

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  • In patients with seasonal allergic rhinitis, quality of life is better outside the peak season and worsens during allergen exposure.

    “As expected in patients with SAR, QOL is better outside of peak season and worsens during allergen exposure.690,691”

    From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [690]

    The Discussion links exposure to pollen or animal dander with allergic symptoms and possible subsequent impairments in health-related quality of life. It does not compare quality of life inside and outside peak season, or establish the claimed seasonal pattern in patients with seasonal allergic rhinitis. (LLM, conf=0.72)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 1

  1. De Graaf-in 't Veld T, Koenders S, Garrelds IM, Gerth van Wijk R. Rela- tionship between nasal hyperreactivity, quality of life and nasal symp- toms in perennial rhinitis. J Allergy Clin Immunol 1996;98:508-13.

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Authors
Juniper, E. F., Rohrbaugh, T., & Meltzer, E. O.
Affiliations
  • McMaster University Medical Centre (CA)
  • Harbage Consulting (US)
  • Allergy and Asthma Medical Group and Research Center (US)
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
2003-03
Volume
111
Issue
3
Pages
484-490
ISSN
0091-6749 (ISSN-L)
OpenAlex
W1966644554
Cited by
115
References
16
Citations by year
2026: 1 · 2025: 1 · 2024: 4 · 2023: 4 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 3 · 2013: 4 · 2012: 7
FWCI
3.15
Type
journal article
Language
en
Open access
Locations
  • Journal of Allergy and Clinical Immunology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
  • Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
  • Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
Keywords
quality of life, questionnaire development, sleep disorders, symptom burden, functional disability, construct validity, responsiveness, reliability statistics
MeSH terms
Adult, Circadian Rhythm, Conjunctivitis, Allergic, Female, Rhinitis, Allergic, Seasonal, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Rhinitis, Allergic, Perennial

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