The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Trim5α protein restricts both HIV-1 and murine leukemia virus
Open accessAbstract
Replication of HIV-1 and N-tropic murine leukemia virus (N-MLV) is restricted in a number of different primate cells. In some cell lines, cross-saturation experiments suggest that the two viruses are interacting with the same restriction factor. Recently, Trim5α protein from rhesus monkey was found to restrict HIV-1. We have confirmed this result and have shown that Trim5α from two African green monkey cell lines, Vero and CV-1, also restricts HIV-1. In addition, we show that human, rhesus, and African green monkey Trim5α can restrict N-MLV. By using a panel of MLV capsid mutants, subtle differences in the anti-MLV activity were identified among the different primate Trim5α cDNAs. Trim1 isolated from humans and green monkeys was also found to restrict N-MLV. We hypothesize that the Trim family of proteins plays a widespread role in innate immunity to viral infection.
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Cites
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
Naldini, L., Blömer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996) · Science · doi:10.1126/science.272.5259.263 · Cited by 4,903
Constructing primate phylogenies from ancient retrovirus sequences
Johnson, W. E., & Coffin, J. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10254 · Cited by 199
Bainbridge, J., Stephens, C., Parsley, K., Demaison, C., Halfyard, A., Thrasher, A., & Ali, R. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301574 · Cited by 197
Short, K. M., Hopwood, B., Yi, Z., & Cox, T. C. (2002) · BMC Cell Biology · doi:10.1186/1471-2121-3-1 · Cited by 137
Cited by
TRIM family proteins and their emerging roles in innate immunity
Ozato, K., Shin, D.-M., Chang, T.-H., & Morse, H. C. (2008) · Nature Reviews Immunology · doi:10.1038/nri2413 · Cited by 1,120
TRIM family proteins: retroviral restriction and antiviral defence
Nisole, S., Stoye, J. P., & Saïb, A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1248 · Cited by 761
Self-citationSawyer, S. L., Wu, L. I., Emerman, M., & Malik, H. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409853102 · Cited by 688
Effects of Retroviruses on Host Genome Function
Jern, P., & Coffin, J. M. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.42.110807.091501 · Cited by 499
Stremlau, M., Perron, M., Welikala, S., & Sodroski, J. (2005) · Journal of Virology · doi:10.1128/jvi.79.5.3139-3145.2005 · Cited by 373
Metadata
- Authors
- Yap, M. W., Nisole, S., Lynch, C., & Stoye, J. P.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2004-07-12
- Volume
- 101
- Issue
- 29
- Pages
- 10786-10791
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1965849042
- Cited by
- 455
- References
- 4
- FWCI
- 14.00
- Type
- journal article
- Language
- en
- Open access
- green
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