The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Structural flexibility in the Burkholderia mallei genome
Open accessAbstract
The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. B. mallei , the etiologic agent of glanders, has come under renewed scientific investigation as a result of recent concerns about its past and potential future use as a biological weapon. Genome analysis identified a number of putative virulence factors whose function was supported by comparative genome hybridization and expression profiling of the bacterium in hamster liver in vivo . The genome contains numerous insertion sequence elements that have mediated extensive deletions and rearrangements of the genome relative to Burkholderia pseudomallei . The genome also contains a vast number (>12,000) of simple sequence repeats. Variation in simple sequence repeats in key genes can provide a mechanism for generating antigenic variation that may account for the mammalian host's inability to mount a durable adaptive immune response to a B. mallei infection.
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Cites
The Pfam Protein Families Database
Bateman, A. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.276 · Cited by 14,000
Principles and Practice of Infectious Diseases.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-818_5 · Cited by 12,025
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
Fleischmann, R. D., Adams, M. D., White, O., Clayton, R. A., Kirkness, E. F., Kerlavage, A. R., Bult, C. J., Tomb, J.-F., Dougherty, B. A., Merrick, J. M., et al. (1995) · Science · doi:10.1126/science.7542800 · Cited by 5,654
Self-citationThe Pfam Protein Families Database
Bateman, A. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.1.263 · Cited by 1,256
Microbial gene identification using interpolated Markov models
Salzberg, S. L., Delcher, A. L., Kasif, S., & White, O. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.2.544 · Cited by 996
Self-citationGenomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
Holden, M. T. G., Titball, R. W., Peacock, S. J., Cerdeño-Tárraga, A. M., Atkins, T., Crossman, L. C., Pitt, T., Churcher, C., Mungall, K., Bentley, S. D., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403302101 · Cited by 758
Self-citationComplete genome sequence of Caulobacter crescentus
Nierman, W. C., Feldblyum, T. V., Laub, M. T., Paulsen, I. T., Nelson, K. E., Eisen, J., Heidelberg, J. F., Alley, M. R. K., Ohta, N., Maddock, J. R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061029298 · Cited by 522
Self-citationTIGRFAMs: a protein family resource for the functional identification of proteins
Haft, D. H. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.1.41 · Cited by 488
Self-citationBiological Warfare: A Historical Perspective
Christopher, L. G. W. (1997) · JAMA · doi:10.1001/jama.1997.03550050074036 · Cited by 417
Functions of the gene products of Escherichia coli
Riley, M. A. (1993) · Microbiological Reviews · doi:10.1128/mmbr.57.4.862-952.1993 · Cited by 367
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Gevers, D., Cohan, F. M., Lawrence, J. G., Spratt, B. G., Coenye, T., Feil, E. J., Stackebrandt, E., de Peer, Y. V., Vandamme, P., Thompson, F. L., et al. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1236 · Cited by 1,122
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
Holden, M. T. G., Titball, R. W., Peacock, S. J., Cerdeño-Tárraga, A. M., Atkins, T., Crossman, L. C., Pitt, T., Churcher, C., Mungall, K., Bentley, S. D., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403302101 · Cited by 758
Self-citationMelioidosis: insights into the pathogenicity of Burkholderia pseudomallei
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Specialized metabolites from the microbiome in health and disease
Sharon, G., Garg, N., Debelius, J., Knight, R., Dorrestein, P. C., & Mazmanian, S. K. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.10.016 · Cited by 544
Metadata
- Authors
- Nierman, W. C., DeShazer, D., Kim, H. S., Tettelin, H., Nelson, K. E., Feldblyum, T., Ulrich, R. L., Ronning, C. M., Brinkac, L. M., Daugherty, S. C., Davidsen, T. D., Deboy, R. T., Dimitrov, G., Dodson, R. J., Durkin, A. S., Gwinn, M. L., Haft, D. H., Khouri, H., Kolonay, J. F., Madupu, R., Mohammoud, Y., Nelson, W. C., Radune, D., Romero, C. M., Sarria, S., Selengut, J., Shamblin, C., Sullivan, S. A., White, O., Yu, Y., Zafar, N., Zhou, L., & Fraser, C. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2004-09-17
- Volume
- 101
- Issue
- 39
- Pages
- 14246-14251
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2008338708
- Cited by
- 395
- References
- 20
- FWCI
- 25.44
- Type
- journal article
- Language
- en
- Open access
- green
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- Nierman, W. C., DeShazer, D., Kim, H. S., Tettelin, H., Nelson, K. E., Feldblyum, T., Ulrich, R. L., Ronning, C. M., Brinkac, L. M., Daugherty, S. C., Davidsen, T. D., Deboy, R. T., Dimitrov, G., Dodson, R. J., Durkin, A. S., Gwinn, M. L., Haft, D. H., Khouri, H., Kolonay, J. F., . . . Fraser, C. M. (2004). Structural flexibility in the Burkholderia mallei genome. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0403306101
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
