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Molecular structure of the lecithin ripple phase
Open accessAbstract
Molecular dynamics simulations of lecithin lipid bilayers in water as they are cooled from the liquid crystalline phase show the spontaneous formation of rippled bilayers. The ripple consists of two domains of different length and orientation, connected by a kink. The organization of the lipids in one domain of the ripple is found to be that of a splayed gel; in the other domain the lipids are gel-like and fully interdigitated. In the concave part of the kink region between the domains the lipids are disordered. The results are consistent with the experimental information available and provide an atomic-level model that may be tested by further experiments.
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Functional rafts in cell membranes
Simons, K., & Ikonen, E. (1997) · Nature · doi:10.1038/42408 · Cited by 9,757
Cited by
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Marrink, S. J., de Vries, A. H., & Tieleman, D. P. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.10.006 · Cited by 440
Self-citationBiological and synthetic membranes: What can be learned from a coarse-grained description?
MULLER, M., KATSOV, K., & SCHICK, M. (2006) · Physics Reports · doi:10.1016/j.physrep.2006.08.003 · Cited by 320
Coarse grained protein- lipid model with application to lipoprotein particles
Shih, A. Y., Arkhipov, A., Freddolino, L., & Schulten, K. (2006) · The Journal of Physical Chemistry B · doi:10.1021/jp0550816 · Cited by 267
Metadata
- Authors
- de Vries, A. H., Yefimov, S., Mark, A. E., & Marrink, S. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2005-04-04
- Volume
- 102
- Issue
- 15
- Pages
- 5392-5396
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2064769762
- Cited by
- 180
- References
- 1
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- green
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- de Vries, A. H., Yefimov, S., Mark, A. E., & Marrink, S. J. (2005). Molecular structure of the lecithin ripple phase. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0408249102
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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