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Cited by 455

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Malaria resurgence in the East African highlands: Temperature trends revisited

Open access
Pascual, M., Ahumada, J. A., Chaves, L. F., Rodó, X., Bouma, M.·2006·Proceedings of the National Academy of Sciences

Abstract

The incidence of malaria in the East African highlands has increased since the end of the 1970s. The role of climate change in the exacerbation of the disease has been controversial, and the specific influence of rising temperature (warming) has been highly debated following a previous study reporting no evidence to support a trend in temperature. We revisit this result using the same temperature data, now updated to the present from 1950 to 2002 for four high-altitude sites in East Africa where malaria has become a serious public health problem. With both nonparametric and parametric statistical analyses, we find evidence for a significant warming trend at all sites. To assess the biological significance of this trend, we drive a dynamical model for the population dynamics of the mosquito vector with the temperature time series and the corresponding detrended versions. This approach suggests that the observed temperature changes would be significantly amplified by the mosquito population dynamics with a difference in the biological response at least 1 order of magnitude larger than that in the environmental variable. Our results emphasize the importance of considering not just the statistical significance of climate trends but also their biological implications with dynamical models.

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Metadata

Authors
Pascual, M., Ahumada, J. A., Chaves, L. F., Rodó, X., & Bouma, M.
Venue
Proceedings of the National Academy of Sciences
Published
2006-04-11
Volume
103
Issue
15
Pages
5829-5834
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2142354606
Cited by
455
References
45
FWCI
23.62
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Malaria resurgence in the East African highlands: Temperature trends revisited. https://app.cochat.ai/papers/10.1073/pnas.0508929103
The paper
Pascual, M., Ahumada, J. A., Chaves, L. F., Rodó, X., & Bouma, M. (2006). Malaria resurgence in the East African highlands: Temperature trends revisited. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0508929103

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