Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
Agrelo, Ruben, Cheng, Wen-Hsing, Setien, Fernando, Ropero, Santiago, Espada, Jesus, Fraga, Mario F., Herranz, Michel, Paz, Maria F., Sanchez-Cespedes, Montserrat, Artiga, Maria Jesus, Guerrero, David, Castells, Antoni, von Kobbe, Cayetano, Bohr, Vilhelm A., Esteller, Manel·2006·Proceedings of the National Academy of Sciences
Cited by (263)
Items 201–263 of 263
- The Human Epigenome—Implications for the Understanding of Human DiseaseManel Esteller · 2017 · Elsevier eBooks
- [Epigenetic research progress of anti-tumor drugs].Mouze Liu, Fazhong He, Wei Zhang · 2013 · PubMed
- The epigenome of colorectal cancerMinoru Toyota, Hiromu Suzuki, Yasuhisa Shinomura · 2009 · Current Colorectal Cancer Reports
- Epigenetic Primer for Diagnostic Applications: A window into Personalized MedicineBeth A. McNally, Mark W. Linder, Roland Valdes · 2014 · Personalized Medicine
- The Role of DNA Methylation in CancerSepideh Shahkarami, Samaneh Zoghi, Nima Rezaei · 2020 · Springer eBooks
- Epigenetic Silencing of Progeroid SyndromesRubén Agrelo · 2009 · Springer eBooks
- The Biological Basis of AgingJunko Oshima, George M. Martin, Fuki Marie Hisama · 2013 · Elsevier eBooks
- Epigenetic Mechanisms in Cancer Formation and ProgressionElisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues J. M. Nicolay, Sandra Coral, Michele Maio · 2011 · Wiley eBooks
- The Age of CancerMitch Leslie · 2006 · Science of Aging Knowledge Environment
- Maintaining the unmethylated stateSteven S. Smith · 2013 · Clinical Epigenetics
- The Biological Basis of Aging: Implications for Medical GeneticsJunko Oshima, George M. Martin, Fuki Marie Hisama · 2014 · Elsevier eBooks
- The Influence of Aging and Cellular Senescence on MetastasisFutoshi Okada, Hiroshi Kobayashi · 2011 · Cambridge University Press eBooks
- Methylation Changes in NeoplasiaTim Crook, Eleftheria ChR. Hatzimichael, Justin Stebbing · 2008 · CRC Press eBooks
- Chapter 18 – The Biological Basis of Aging: Implications for Medical GeneticsJunko Oshima, George M. Martin, Fuki Marie Hisama · 2013
- The Human Epigenome: Implications for the Understanding of Human DiseaseMaría Berdasco, Manel Esteller · 2009 · Elsevier eBooks
- Promoter CpG island methylation in colorectal cancer:Sarah Derks A, Manon van Engeland · 2012 · Cambridge University Press eBooks
- Biomarkers in Metastatic Colorectal CancerConnie Irene Diakos, Kellie A. Charles, Wei Ming Chua, Viive Maarika Howell, Stephen John Clarke · 2015 · Biomarkers in disease
- Werner syndrome: a rare mutationAlberto Castagna, Pietro Gareri, Francesca Falvo, Simona Sestito, Maurizio Rocca, Licia Pensabene, Daniela Concolino, Giuseppe Coppolino, Giovanni Ruotolo · 2018 · Aging Clinical and Experimental Research
- WPŁYW METYLACJI DNA NA FUNKCJONOWANIE GENOMUMarcin Łukasik, Jolanta Karmalska, Mirosław M. Szutowski, Jacek Łukaszkiewicz · 2009 · Prospects in Pharmaceutical Sciences
- Alcohol consumption as a risk factor for colorectal cancer : an epidemiological study on genetic susceptibility and molecular endpointsBrenda W. C. Bongaerts · 2008
- DNA Helicase Deficiency DisordersJulia M. Sidorova, Raymond J. Monnat · 2018 · Wiley eBooks
- Gene expression changes in normal haematopoietic cellsJack M. Lionberger, Derek L. Stirewalt · 2009 · Best Practice & Research Clinical Haematology
- Telomere biology: Implications for radiation carcinogenesisSeiji Kodama, Kentaro Ariyoshi, Sanae Watanabe, Kazunori Shiraishi, Masami Watanabe · 2007 · International Congress Series
- Epigenetics in Brain Development and DiseaseElisabeth J. Radford, Anne C. Ferguson‐Smith, Sacri R. Ferrón · 2017 · Wiley eBooks
- Contribución de la epigenética al manejo personalizado del cáncerVerónica Dávalos, Manel Esteller · 2010 · Elsevier eBooks
- Methylation in TumorigenesisA. Melissa, P. Pashayar, Drew R., Adam Mark · 2012 · InTech eBooks
- (Epi-) genetic profiling of colorectal cancer : prognostic and biological relevance, with emphasis on tumor-hypoxiaArjen H.G. Cleven · 2012
- Pharmaco-Epigenomics to Improve Cancer TherapiesBart Claes, Bernard Siebens, Diether Lambrechts · 2012 · Encyclopedia of Molecular Cell Biology and Molecular Medicine
- Análise epigenética e de polimorfismos em tumores extra-axiais do sistema nervosoLuciana O. Almeida · 2009
- Epigenetics and Tumor Suppressor GenesMingzhou Guo, Xuefeng Liu, Weimin Zhang · 2012 · InTech eBooks
- Epigenetic Drivers of Genetic Alterations in CancerHiromu Suzuki · 2012 · Wiley eBooks
- Predicting chemotherapeutic response and toxicity in colorectal cancerConnie Irene Diakos, Wei Ming Chua, Kellie A. Charles, Viive Maarika Howell, Stephen John Clarke · 2013 · Colorectal Cancer
- Genetics and epigenetics in human cancerJie Lv, Hui Liu, Hongbo Liu, Qiong Wu, Yan Zhang · 2014 · Cancer Genetics and Epigenetics
- Regulation of WRN Function by Acetylation and SIRT1-Mediated Deacetylation in Response to DNA Damage: A DissertationKai Li · 2010 · eScholarship@UMassChan
- Utilization of Werner syndrome mouse model in studying premature aging and tumorShuting Jia, Shihua Yang, Ying Luo · 2009 · Hereditas (Beijing)
- Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRNAndreas Bachler, Stephanie W. Cox · 2012
- Werner syndrome: association of premature aging and cancer predispositionByungchan Ahn, Tinna Stevnsner, Vilhelm A. Bohr · 2013 · Cambridge University Press eBooks
- TYPES OF DNA DAMAGE2013 · CRC Press eBooks
- Age-related epigenetic changes at base excision repair genes and their modulation by dietary restriction in miceJoanna Gorniak · 2015
- Genetics: Clues, Not Answers, to the Mysteries of Precision MedicineJules J. Berman · 2018 · Elsevier eBooks
- The Human EpigenomeMaría Berdasco, Manel Esteller · 2010 · Elsevier eBooks
- Evolution and Embryonic DevelopmentJules J. Berman · 2019 · Elsevier eBooks
- Analyse globale des altérations abberantes de la méthylation de l'ADN dans le cancer de l'ovaireMamadou Keita · 2013
- Biomarkers in Metastatic Colorectal CancerConnie Irene Diakos, Kellie A. Charles, Wei Ming Chua, Viive Maarika Howell, Stephen John Clarke · 2014 · Springer eBooks
- Mutational landscape informs the treatment of non-small cell lung cancerRohan Aananth, Meera Chopra, Esra Rakab · 2021 · The Meducator
- Werner SyndromeMaria Stylianou, Xenia Anastassiou‐Hadjicharalambous · 2011 · Springer eBooks
- Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemiaYuslina Mat Yusoff, Fadly Ahid, Zahidah Abu Seman, Julia Abdullah, Nor Rizan Kamaluddin, Ezalia Esa, Zubaidah Zakaria · 2021 · Research Square
- Glossary2014 · Elsevier eBooks
- PathoprofileRohan Aananth, Meera Chopra, Esra Rakab · 2020 · The Meducator
- DNA Helicase‐deficiency DisordersJulia M. Sidorova, Raymond J. Monnat · 2010 · Wiley eBooks
- In Brief2006 · Nature reviews. Cancer
- Prognostic significance of aberrant CpG islands methylation in human follicular and diffuse large B-cell lymphomaMilena Krajnović · 2013
- Faculty Opinions recommendation of WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy.Vilhelm A. Bohr · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Epigenetic therapy and DNA damage responseMarina Baretti, Nilofer Saba Azad · 2022 · Elsevier eBooks
- Supplementary Figure 1 from RECQL1 and WRN Proteins Are Potential Therapeutic Targets in Head and Neck Squamous Cell CarcinomaAkihito Arai, Tokuhiro Chano, Kazunobu Futami, Yasuhiro Furuichi, Kaichiro Ikebuchi, Takuma Inui, Hitosuke Tameno, Yasuko Ochi, Taketoshi Shimada, Yasuo Hisa et al. · 2023
- Epigenetic Contributions to Human CancerJames Gordon Herman, Stephen B. Baylin · 2017 · Wiley eBooks
- James German and the Quest to Understand Human RECQ Helicase DeficienciesRaymond J. Monnat · 2024 · Cells
- Whole Exome Sequencing Identifies a Novel Frameshift Mutation of the WRN Gene in a Werner Syndrome Family and Functional AnalysisHao Xiong, Haiqing Gao, Jianji Wan, Jieping Xiao, Xiaoqun Luo, Xiuqin Dong, Yueheng Wu, Tao Liu · 2025 · Molecular Genetics & Genomic Medicine
- WRN helicase upregulates mitophagy by resolving an intricate nexus of G-quadruplexes-R loops-ATG7 pre-mRNA maturation in cancerPooja Gupta, Mrityunjay Tyagi, Ananda Guha Majumdar, Ganesh Pai Bellare, Saikat Chakraborty, Shambhavi Mishra, Megha Tawate, Avik Chakraborty, Sujit K. Bhutia, Birija Sankar Patro · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Etude de la régulation de l’expression de PLAGL1 dans les sarcomesAnne-Lise Peille · 2010 · theses.fr (ABES)
- Réparation des cassures double brin de l'adn chez les mammifères : rôle des protéines MRE11 et BLM dans l’initiation de la ligature d’extrémités non homologues (NHEJ )Anastazja Grabarz · 2011 · theses.fr (ABES)
- The interplay between genetics and epigenetics in colorectal cancerSarah Derks · 2009 · Research Publications (Maastricht University)
- The epigenetic regulation of chemotherapy resistance in melanomaHussein Abdul-Hassan Tawbi · 2011 · D-Scholarship@Pitt (University of Pittsburgh)