Esteller, Manel

Non-coding RNAs in human disease

Esteller, M. (2011) · Nature Reviews Genetics

Cancer-related molecular mechanisms researchMicroRNA in disease regulation

Cited by 4,825

Epigenetic differences arise during the lifetime of monozygotic twins

Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 3,602

The Polycomb group protein EZH2 directly controls DNA methylation

Viré, E., Brenner, C., Deplus, R., Blanchon, L., Fraga, M., Didelot, C., Morey, L., Van Eynde, A., Bernard, D., Vanderwinden, J.-M., et al. (2006) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,204

A Landscape of Pharmacogenomic Interactions in Cancer

Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N., Gonçalves, E., Barthorpe, S., Lightfoot, H., et al. (2016) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 2,090

Global epigenomic reconfiguration during mammalian brain development

Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., Lucero, J., Huang, Y., Dwork, A. J., Schultz, M. D., et al. (2013) · Science

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 1,830

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

Esteller, M. (2000) · Journal of the National Cancer Institute

BRCA gene mutations in cancerEpigenetics and DNA Methylation

Cited by 1,233

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

Sandoval, J., Heyn, H., Moran, S., Serra-Musach, J., Pujana, M. A., Bibikova, M., & Esteller, M. (2011) · Epigenetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 990

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

Sia, D., Jiao, Y., Martinez-Quetglas, I., Kuchuk, O., Villacorta-Martin, C., Castro de Moura, M., Putra, J., Camprecios, G., Bassaganyas, L., Akers, N., et al. (2017) · Gastroenterology

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 976

Distinct DNA methylomes of newborns and centenarians

Heyn, H., Li, N., Ferreira, H. J., Moran, S., Pisano, D. G., Gomez, A., Diez, J., Sanchez-Mut, J. V., Setien, F., Carmona, F. J., et al. (2012) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 802

Epigenetic gene silencing in cancer: the DNA hypermethylome

Esteller, M. (2007) · Human Molecular Genetics

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 725

Epigenetics and aging: the targets and the marks

Fraga, M. F., & Esteller, M. (2007) · Trends in Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 690

DNA methylation contributes to natural human variation

Heyn, H., Moran, S., Hernando-Herraez, I., Sayols, S., Gomez, A., Sandoval, J., Monk, D., Hata, K., Marques-Bonet, T., Wang, L., et al. (2013) · Genome Research

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 408

A Role for RNAi in the Selective Correction of DNA Methylation Defects

Teixeira, F. K., Heredia, F., Sarazin, A., Roudier, F., Boccara, M., Ciaudo, C., Cruaud, C., Poulain, J., Berdasco, M., Fraga, M. F., et al. (2009) · Science

Epigenetics and DNA MethylationPlant Molecular Biology Research

Cited by 358

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

Gonzalo, S., García-Cao, M., Fraga, M. F., Schotta, G., Peters, A. H. F. M., Cotter, S. E., Eguía, R., Dean, D. C., Esteller, M., Jenuwein, T., et al. (2005) · Nature Cell Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 343

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

Agrelo, R., Cheng, W.-H., Setien, F., Ropero, S., Espada, J., Fraga, M. F., Herranz, M., Paz, M. F., Sanchez-Cespedes, M., Artiga, M. J., et al. (2006) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

Cited by 264

Cross‐Talk between Aging and Cancer: The Epigenetic Language

FRAGA, M. F., AGRELO, R., & ESTELLER, M. (2007) · Annals of the New York Academy of Sciences

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 251

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

Léveillé, N., Melo, C. A., Rooijers, K., Díaz-Lagares, A., Melo, S. A., Korkmaz, G., Lopes, R., Moqadam, F. A., Maia, A. R., Wijchers, P. J., et al. (2015) · Nature Communications

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 183

DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

Sanchez-Mut, J. V., Aso, E., Panayotis, N., Lott, I., Dierssen, M., Rabano, A., Urdinguio, R. G., Fernandez, A. F., Astudillo, A., Martin-Subero, J. I., et al. (2013) · Brain

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 144

Effects of APOE ‐ε4 allele load on brain morphology in a cohort of middle‐aged healthy individuals with enriched genetic risk for Alzheimer's disease

Cacciaglia, R., Molinuevo, J. L., Falcón, C., Brugulat‐Serrat, A., Sánchez‐Benavides, G., Gramunt, N., Esteller, M., Morán, S., Minguillón, C., Fauria, K., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 124

MeCP2: the long trip from a chromatin protein to neurological disorders

Ausió, J., Paz, A. M. D., & Esteller, M. (2014) · Trends in Molecular Medicine

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 108

Hot topics in epigenetic mechanisms of aging: 2011

Berdasco, M., & Esteller, M. (2012) · Aging Cell

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 86

The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

Subtil-Rodríguez, A., Vázquez-Chávez, E., Ceballos-Chávez, M., Rodríguez-Paredes, M., Martín-Subero, J. I., Esteller, M., & Reyes, J. C. (2014) · Nucleic Acids Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 83

Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease

Garcia-Gomez, A., Li, T., de la Calle-Fabregat, C., Rodríguez-Ubreva, J., Ciudad, L., Català-Moll, F., Godoy-Tena, G., Martín-Sánchez, M., San-Segundo, L., Muntión, S., et al. (2021) · Nature Communications

Multiple Myeloma Research and TreatmentsEpigenetics and DNA Methylation

Cited by 57

Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects

Operto, G., Molinuevo, J. L., Cacciaglia, R., Falcon, C., Brugulat-Serrat, A., Suárez-Calvet, M., Grau-Rivera, O., Bargalló, N., Morán, S., Esteller, M., et al. (2019) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 40