Fraga, Mario F.

Epigenetic differences arise during the lifetime of monozygotic twins

Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 3,602

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., LeBleu, V. S., Mittendorf, E. A., Weitz, J., Rahbari, N., et al. (2015) · Nature

Extracellular vesicles in diseaseCancer Genomics and Diagnostics

Cited by 2,880

The Polycomb group protein EZH2 directly controls DNA methylation

Viré, E., Brenner, C., Deplus, R., Blanchon, L., Fraga, M., Didelot, C., Morey, L., Van Eynde, A., Bernard, D., Vanderwinden, J.-M., et al. (2006) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,204

Epigenetics and the environment: emerging patterns and implications

Feil, R., & Fraga, M. F. (2012) · Nature Reviews Genetics

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 1,929

Distinct DNA methylomes of newborns and centenarians

Heyn, H., Li, N., Ferreira, H. J., Moran, S., Pisano, D. G., Gomez, A., Diez, J., Sanchez-Mut, J. V., Setien, F., Carmona, F. J., et al. (2012) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 802

Epigenetics and aging: the targets and the marks

Fraga, M. F., & Esteller, M. (2007) · Trends in Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 690

A Role for RNAi in the Selective Correction of DNA Methylation Defects

Teixeira, F. K., Heredia, F., Sarazin, A., Roudier, F., Boccara, M., Ciaudo, C., Cruaud, C., Poulain, J., Berdasco, M., Fraga, M. F., et al. (2009) · Science

Epigenetics and DNA MethylationPlant Molecular Biology Research

Cited by 358

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

Gonzalo, S., García-Cao, M., Fraga, M. F., Schotta, G., Peters, A. H. F. M., Cotter, S. E., Eguía, R., Dean, D. C., Esteller, M., Jenuwein, T., et al. (2005) · Nature Cell Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 343

The role of epigenetics in aging and age-related diseases

Calvanese, V., Lara, E., Kahn, A., & Fraga, M. F. (2009) · Ageing Research Reviews

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 329

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

Agrelo, R., Cheng, W.-H., Setien, F., Ropero, S., Espada, J., Fraga, M. F., Herranz, M., Paz, M. F., Sanchez-Cespedes, M., Artiga, M. J., et al. (2006) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

Cited by 264

Cross‐Talk between Aging and Cancer: The Epigenetic Language

FRAGA, M. F., AGRELO, R., & ESTELLER, M. (2007) · Annals of the New York Academy of Sciences

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 251

Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan

Gokhman, D., Lavi, E., Prüfer, K., Fraga, M. F., Riancho, J. A., Kelso, J., Pääbo, S., Meshorer, E., & Carmel, L. (2014) · Science

Epigenetics and DNA MethylationPleistocene-Era Hominins and Archaeology

Cited by 221

DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

Sanchez-Mut, J. V., Aso, E., Panayotis, N., Lott, I., Dierssen, M., Rabano, A., Urdinguio, R. G., Fernandez, A. F., Astudillo, A., Martin-Subero, J. I., et al. (2013) · Brain

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 144

Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Chondronasiou, D., Gill, D., Mosteiro, L., Urdinguio, R. G., Berenguer‐Llergo, A., Aguilera, M., Durand, S., Aprahamian, F., Nirmalathasan, N., Abad, M., et al. (2022) · Aging Cell

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 133

Aging and cancer epigenetics: Where do the paths fork?

Pérez, R. F., Tejedor, J. R., Fernández, A. F., & Fraga, M. F. (2022) · Aging Cell

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 44

LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk

Salas, L. A., Villanueva, C. M., Tajuddin, S. M., Amaral, A. F. S., Fernandez, A. F., Moore, L. E., Carrato, A., Tardón, A., Serra, C., García-Closas, R., et al. (2014) · Epigenetics

Epigenetics and DNA MethylationWater Treatment and Disinfection

Cited by 34

Epigenetics and aging: status, challenges, and needs for the future

Kahn, A., & Fraga, M. F. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 29