The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester
Open accessAbstract
Phenylpropenes such as chavicol, t -anol, eugenol, and isoeugenol are produced by plants as defense compounds against animals and microorganisms and as floral attractants of pollinators. Moreover, humans have used phenylpropenes since antiquity for food preservation and flavoring and as medicinal agents. Previous research suggested that the phenylpropenes are synthesized in plants from substituted phenylpropenols, although the identity of the enzymes and the nature of the reaction mechanism involved in this transformation have remained obscure. We show here that glandular trichomes of sweet basil ( Ocimum basilicum ), which synthesize and accumulate phenylpropenes, possess an enzyme that can use coniferyl acetate and NADPH to form eugenol. Petunia ( Petunia hybrida cv. Mitchell) flowers, which emit large amounts of isoeugenol, possess an enzyme homologous to the basil eugenol-forming enzyme that also uses coniferyl acetate and NADPH as substrates but catalyzes the formation of isoeugenol. The basil and petunia phenylpropene-forming enzymes belong to a structural family of NADPH-dependent reductases that also includes pinoresinol–lariciresinol reductase, isoflavone reductase, and phenylcoumaran benzylic ether reductase.
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An Investigation of the Storage and Biosynthesis of Phenylpropenes in Sweet Basil
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Self-citationUnderstanding in Vivo Benzenoid Metabolism in Petunia Petal Tissue
Boatright, J., Negre, F., Chen, X., Kish, C. M., Wood, B., Peel, G., Orlova, I., Gang, D., Rhodes, D., & Dudareva, N. (2004) · Plant Physiology · doi:10.1104/pp.104.045468 · Cited by 461
Self-citationODORANT1 Regulates Fragrance Biosynthesis in Petunia Flowers
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Characterization of Geraniol Synthase from the Peltate Glands of Sweet Basil
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Self-citationRegulation of floral scent production in petunia revealed by targeted metabolomics
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Self-citationAntibacterial activity of essential oil components
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Structure and function of enzymes involved in the biosynthesis of phenylpropanoids
Ferrer, J.-L., Austin, M. B., Stewart, C., & Noel, J. P. (2008) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2007.12.009 · Cited by 873
Self-citationConvergent Evolution in Plant Specialized Metabolism
Pichersky, E., & Lewinsohn, E. (2011) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103814 · Cited by 523
Self-citationSites of synthesis, biochemistry and functional role of plant volatiles
Maffei, M. E. (2010) · South African Journal of Botany · doi:10.1016/j.sajb.2010.03.003 · Cited by 342
Avetisyan, A., Markosian, A., Petrosyan, M., Sahakyan, N., Babayan, A., Aloyan, S., & Trchounian, A. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-1587-5 · Cited by 186
Bao, F., Zhang, T., Ding, A., Ding, A., Yang, W., Wang, J., Cheng, T., & Zhang, Q. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.574982 · Cited by 15
Metadata
- Authors
- Koeduka, T., Fridman, E., Gang, D. R., Vassão, D. G., Jackson, B. L., Kish, C. M., Orlova, I., Spassova, S. M., Lewis, N. G., Noel, J. P., Baiga, T. J., Dudareva, N., & Pichersky, E.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2006-06-27
- Volume
- 103
- Issue
- 26
- Pages
- 10128-10133
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2149115900
- Cited by
- 417
- References
- 23
- FWCI
- 6.75
- Type
- journal article
- Language
- en
- Open access
- green
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- Koeduka, T., Fridman, E., Gang, D. R., Vassão, D. G., Jackson, B. L., Kish, C. M., Orlova, I., Spassova, S. M., Lewis, N. G., Noel, J. P., Baiga, T. J., Dudareva, N., & Pichersky, E. (2006). Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0603732103
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