The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
Embryo stability and vulnerability in an always changing world
Open accessAbstract
Contrary to the view that embryos and larvae are the most fragile stages of life, development is stable under real-world conditions. Early cleavage embryos are prepared for environmental vagaries by having high levels of cellular defenses already present in the egg before fertilization. Later in development, adaptive responses to the environment either buffer stress or produce alternative developmental phenotypes. These buffers, defenses, and alternative pathways set physiological limits for development under expected conditions; teratology occurs when embryos encounter unexpected environmental changes and when stress exceeds these limits. Of concern is that rapid anthropogenic changes to the environment are beyond the range of these protective mechanisms.
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Citations
Cites
Developmental Plasticity and Evolution
West-Eberhard, M. J. (2003) · doi:10.1093/oso/9780195122343.001.0001 · Cited by 6,115
Anthropogenic carbon and ocean pH
Caldeira, K., & Wickett, M. E. (2003) · Nature · doi:10.1038/425365a · Cited by 3,549
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
Hartl, F. U., & Hayer-Hartl, M. (2002) · Science · doi:10.1126/science.1068408 · Cited by 3,347
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility
Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563
Hsp90 as a capacitor for morphological evolution
Rutherford, S. L., & Lindquist, S. (1998) · Nature · doi:10.1038/24550 · Cited by 2,270
BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER
Ambudkar, S. V., Dey, S., Hrycyna, C. A., Ramachandra, M., Pastan, I., & Gottesman, M. M. (1999) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.39.1.361 · Cited by 2,059
Living with the Past: Evolution, Development, and Patterns of Disease
Gluckman, P. D., & Hanson, M. A. (2004) · Science · doi:10.1126/science.1095292 · Cited by 1,921
A genomic regulatory network for development
Davidson, E. H., Rast, J. P., Oliveri, P., Ransick, A., Calestani, C., Yuh, C.-H., Minokawa, T., Amore, G., Hinman, V., Arenas-Mena, C., et al. (2002) · Science · doi:10.1126/science.1069883 · Cited by 1,567
The Biology of heat shock proteins and molecular chaperones.
Morimoto, R. I., Tissieres, A., & Georgopoulos, C. P. (1994) · Cold Spring Harbor Laboratory eBooks · Cited by 1,243
The biology of heat shock proteins and molecular chaperones
Buchner, J. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90065-5 · Cited by 1,205
Cited by
Sokolova, I. M. (2013) · Integrative and Comparative Biology · doi:10.1093/icb/ict028 · Cited by 719
Melzner, F., Gutowska, M. A., Langenbuch, M., Dupont, S., Lucassen, M., Thorndyke, M. C., Bleich, M., & Pörtner, H.-O. (2009) · Biogeosciences · doi:10.5194/bg-6-2313-2009 · Cited by 667
Living in the Now: Physiological Mechanisms to Tolerate a Rapidly Changing Environment
Hofmann, G. E., & Todgham, A. E. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135900 · Cited by 632
Byrne, M., & Przeslawski, R. (2013) · Integrative and Comparative Biology · doi:10.1093/icb/ict049 · Cited by 388
Impact of near-future ocean acidification on echinoderms
Dupont, S., Ortega-Martínez, O., & Thorndyke, M. (2010) · Ecotoxicology · doi:10.1007/s10646-010-0463-6 · Cited by 381
Metadata
- Authors
- Hamdoun, A., & Epel, D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2007-02-06
- Volume
- 104
- Issue
- 6
- Pages
- 1745-1750
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1985682875
- Cited by
- 388
- References
- 80
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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