The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking through PKA phosphorylation of the Glu receptor 1 subunit
Open accessAbstract
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors mediate the majority of excitatory synaptic transmission in the brain. Recent studies have shown that activation of PKA regulates the membrane trafficking of the AMPA receptor Glu receptor 1 (GluR1) subunit, but the role of direct phosphorylation of GluR1 in regulating receptor redistribution is not clear. Here we show that phosphorylation of the GluR1 subunit on serine 845 by PKA is required for PKA-induced increases in AMPA receptor cell-surface expression because it promotes receptor insertion and decreases receptor endocytosis. Furthermore, dephosphorylation of GluR1 serine 845 triggers NMDA-induced AMPA receptor internalization. These findings strongly suggest that dynamic changes in direct phosphorylation of GluR1 by PKA are crucial in the modulation of AMPA receptor trafficking and synaptic plasticity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“During LTD, S845 is dephosphorylated by activation of CaN, PP1 and PP2A, removed from synapses, and endocytosed from the extrasynaptic membrane”
From AKAP150-Anchored Calcineurin Regulates Synaptic Plasticity by Limiting Synaptic Incorporation of Ca2+-Permeable AMPA Receptors (2012) · cites this paper as Man et al., 2007
In the citing paper
“Phosphorylation of S845 increases single channel open–probability and also promotes GluA1 targeting or retention to the cell surface (Banke et al., 2000, Oh et al., 2006, Man et al., 2007).”
From The AMPA Receptor Code of Synaptic Plasticity (2018) · cites this paper as Man et al., 2007
Citations
Cites
Glutamate neurotoxicity and diseases of the nervous system
Choi, D. W. (1988) · Neuron · doi:10.1016/0896-6273(88)90162-6 · Cited by 8,188
AMPA Receptor Trafficking and Synaptic Plasticity
Malinow, R., & Malenka, R. C. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142758 · Cited by 2,588
MAPK cascade signalling and synaptic plasticity
Thomas, G. M., & Huganir, R. L. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1346 · Cited by 1,454
Self-citationAMPA receptor trafficking at excitatory synapses
Bredt, D. S., & Nicoll, R. A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00640-8 · Cited by 1,150
Reinsertion or Degradation of AMPA Receptors Determined by Activity-Dependent Endocytic Sorting
Ehlers, M. D. (2000) · Neuron · doi:10.1016/s0896-6273(00)00129-x · Cited by 1,096
Receptor trafficking and synaptic plasticity
Collingridge, G. L., Isaac, J. T. R., & Wang, Y. T. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1556 · Cited by 1,046
Lu, W.-Y., Man, H., Ju, W. H., Trimble, W. S., MacDonald, J. F., & Wang, Y. T. (2001) · Neuron · doi:10.1016/s0896-6273(01)00194-5 · Cited by 935
Self-citationPKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
Esteban, J. A., Shi, S.-H., Wilson, C., Nuriya, M., Huganir, R. L., & Malinow, R. (2003) · Nature Neuroscience · doi:10.1038/nn997 · Cited by 894
Self-citationLee, H.-K., Takamiya, K., Han, J.-S., Man, H., Kim, C.-H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R. S., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00122-3 · Cited by 802
Self-citationRegulation of AMPA receptors during synaptic plasticity
Song, I., & Huganir, R. L. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02270-1 · Cited by 798
Self-citation
Cited by
Sorted by citations
Items 201–300 of 310
Prikhodko, O., Freund, R. K., Sullivan, E. M., Kennedy, M. J., & Dell’Acqua, M. L. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0675-24.2024 · Cited by 16
Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus
Ojeda-Juárez, D., Lawrence, J. A., Soldau, K., Pizzo, D. P., Wheeler, E. C., Aguilar‐Calvo, P., Khuu, H., Chen, J., Malik, A., Funk, G., et al. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105834 · Cited by 15
Werner, C. T., Murray, C. H., Reimers, J. M., Chauhan, N. M., Woo, K., Molla, H. M., Loweth, J. A., & Wolf, M. E. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.12.014 · Cited by 15
Hwang, Y., Kim, H., & Shin, E. (2021) · Toxicology · doi:10.1016/j.tox.2021.152887 · Cited by 16
Nair, J. D., Braksator, E., Yucel, B. P., Fletcher-Jones, A., Seager, R., Mellor, J. R., Bashir, Z. I., Wilkinson, K. A., & Henley, J. M. (2021) · iScience · doi:10.1016/j.isci.2021.103029 · Cited by 15
Augmentation of Fear Extinction by Infusion of Glycine Transporter Blockers into the Amygdala
Mao, S.-C., Lin, H., & Gean, P. (2009) · Molecular Pharmacology · doi:10.1124/mol.108.053728 · Cited by 16
He, Y., Kulasiri, D., & Samarasinghe, S. (2014) · Biosystems · doi:10.1016/j.biosystems.2014.06.005 · Cited by 15
Oh, J. H., Yang, J. H., Ahn, S., Youn, B., Choi, B.-T., Wang, J. Q., & Choe, E. S. (2013) · Psychopharmacology · doi:10.1007/s00213-013-2968-1 · Cited by 15
Kinase and phosphatase engagement is dissociated between memory formation and extinction
Pagani, M. R., & Merlo, E. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00038 · Cited by 14
Guercio, L. A., Hofmann, M. E., Swinford-Jackson, S. E., Sigman, J. S., Wimmer, M. E., Dell’Acqua, M. L., Schmidt, H. D., & Pierce, R. C. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.297 · Cited by 13
Mao, L., Diaz, J. A., Fibuch, E. E., & Wang, J. Q. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.05.027 · Cited by 14
Nooh, M. M., Naren, A. P., Kim, S.-J., Xiang, Y. K., & Bahouth, S. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063379 · Cited by 14
Zhang, X., Tsuboi, D., Funahashi, Y., Yamahashi, Y., Kaibuchi, K., & Nagai, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911643 · Cited by 15
Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking
Cao, J., Tan, H., Mi, W., & Zuo, Z. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.01.006 · Cited by 12
Peng, X., de Vaca, S. C., Ziff, E. B., & Carr, K. D. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3476-7 · Cited by 16
Fast Regulation of GABAAR Diffusion Dynamics by Nogo-A Signaling
Fricke, S., Metzdorf, K., Ohm, M., Haak, S., Heine, M., Körte, M., & Zagrebelsky, M. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.09.015 · Cited by 13
Wang, S., Cai, Q., Xu, L., Sun, Y., Wang, M., Wang, Y., Zhang, L., Li, K., & Ni, Z. (2023) · Psychopharmacology · doi:10.1007/s00213-023-06413-8 · Cited by 13
Ji, E., Zhang, Y., Li, Z., Wei, L., Wu, Z., Li, Y., Yu, X., & Song, T.-J. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01236-9 · Cited by 14
Zheng, D., de Vaca, S. C., Jurkowski, Z., & Carr, K. D. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3863-8 · Cited by 14
Lisman, J. E., & Hell, J. W. (2008) · Springer eBooks · doi:10.1007/978-0-387-77232-5_17 · Cited by 12
Protein kinase D promotes activity‐dependent AMPA receptor endocytosis in hippocampal neurons
Morales, C. O. O., Ignácz, A., Bencsik, N., Szíber, Z., Rátkai, A. E., Lieb, W. S., Eisler, S. A., Szűcs, A. L., Schlett, K., & Haußer, A. (2021) · Traffic · doi:10.1111/tra.12819 · Cited by 10
Kokane, S. S., Cole, R. D., Bordieanu, B., Ray, C. M., Haque, I. A., Otis, J. M., & McGinty, J. F. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0108-23.2023 · Cited by 12
Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function
Fernández‐Suárez, D., Krapacher, F. A., Pietrajtis, K., Andersson, A. K., Kisiswa, L., Carrier‐Ruiz, A., Diana, M. A., & Ibáñez, C. F. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001350 · Cited by 11
Activity of Protein Kinase A in the Frontal Cortex in Schizophrenia
Sahay, S., Henkel, N., Vargas, C. F.-A., McCullumsmith, R. E., & O'Donovan, S. M. (2023) · Brain Sciences · doi:10.3390/brainsci14010013 · Cited by 11
Delhaye, S., Jarjat, M., Boulksibat, A., Sanchez, C., Tempio, A., Turtoï, A., Giorgi, M., Lacas‐Gervais, S., Baj, G., Rovère, C., et al. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106393 · Cited by 11
Gray, E. E., Guglietta, R., Khakh, B. S., & O’Dell, T. J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.553537 · Cited by 12
Hastings, M. H., Gauthier, J. M., Mabry, K., Tran, A., Man, H., & Kantak, K. M. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112596 · Cited by 11
Self-citationRoles of Phosphotase 2A in Nociceptive Signal Processing
Wang, Y., Lei, Y., Li, F., Mu, Y., Wu, J., & Zhang, X. (2013) · Molecular Pain · doi:10.1186/1744-8069-9-46 · Cited by 11
Li, Y., Han, L., Wu, K. L., & Chan, Y. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.05.005 · Cited by 10
Dysfunction of EAAT3 Aggravates LPS-Induced Post-Operative Cognitive Dysfunction
Wang, X., Ma, Y., Hou, A., Song, Y., Sui, X., Liu, W., Liu, M., Wang, Y., Cao, J., & 米卫东 (2022) · Membranes · doi:10.3390/membranes12030317 · Cited by 10
Protein kinases in natural versus drug reward
Amaral, I. M., Scheffauer, L., Hofer, A., & Rawas, R. E. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173472 · Cited by 10
Chemokine CXCL8 modulates GluR1 phosphorylation
Catalano, M., Trettel, F., Cipriani, R., Lauro, C., Sobrero, F., Eusebi, F., & Limatola, C. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.04.017 · Cited by 10
Fang, X.-Q., Qiao, H., Groveman, B. R., Feng, S., Pflueger, M., Xin, W.-K., Ali, M. K., Lin, S.-X., Xu, J., Duclot, F., et al. (2015) · Molecular Brain · doi:10.1186/s13041-015-0167-1 · Cited by 12
Hao, F., Bu, Y., Huang, S., Li, W., Feng, H., & Wang, Y. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116196 · Cited by 10
Cabrera‐Pastor, A., Taoro‐González, L., López-Merino, E., Celma, F., Llansola, M., & Felipo, V. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.10.031 · Cited by 9
Endocytosis of AMPA receptors: Role in neurological conditions
Bencsik, N., Morales, C. O. O., Haußer, A., & Schlett, K. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2022.09.007 · Cited by 9
General anesthetics as a factor of effective neuroprotection in ischemic stroke models
Лалетин, В. С., & Bykov, Y. N. (2015) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20156104440 · Cited by 8
Xue, B., Edwards, M. C., Mao, L., Guo, M., Jin, D.-Z., Fibuch, E. E., & Wang, J. Q. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.11.001 · Cited by 8
Zavvari, F., Mousavi, S. M. M., Ejlali, M., Barfi, S., & Karimzadeh, F. (2020) · PubMed Central · doi:10.22037/ijpr.2020.112638.13869 · Cited by 8
Long-Term Shaping of Corticostriatal Synaptic Activity by Acute Fasting
Campanelli, F., Laricchiuta, D., Natale, G., Marino, G., Calabrese, V., Picconi, B., Petrosini, L., Calabresi, P., & Ghiglieri, V. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041916 · Cited by 8
Babiec, W. E., Guglietta, R., & O’Dell, T. J. (2016) · Learning & Memory · doi:10.1101/lm.040675.115 · Cited by 8
Taoro‐González, L., Arenas, Y. M., Cabrera‐Pastor, A., & Felipo, V. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1387-z · Cited by 7
Mateo, Z., & Porter, J. T. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2014.12.083 · Cited by 7
Wang, H., Liu, H., Storm, D. R., & Zhang, Z. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.213702 · Cited by 7
Dynamic increases in AMPA receptor phosphorylation in the rat hippocampus in response to amphetamine
Mao, L., Xue, B., Jin, D., & Wang, J. Q. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13067 · Cited by 7
Lee, D.-S., Kim, T. H., Park, H., & Kim, J.-E. (2023) · Scientific Reports · doi:10.1038/s41598-023-41014-7 · Cited by 6
Characterizing spine issues: If offers novel therapeutics to Angelman syndrome
Yang, X. (2020) · Developmental Neurobiology · doi:10.1002/dneu.22757 · Cited by 7
Song, X., Li, W., Shi, Y., Zhang, J., & Li, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.19671 · Cited by 6
Mao, L., He, N., Jin, D.-Z., & Wang, J. Q. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.01.063 · Cited by 5
Liu, X., Huang, Y., Mu, L., Friedman, V., Kelly, T. J., Hu, Y. C., Yuan, D., & Liu, Q.-S. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-02030-x · Cited by 6
Oberlander, J. G., Lin, A. W., Man, H., & Erskine, M. S. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06529.x · Cited by 5
Self-citationRegulation of AMPA Receptor Trafficking in the Nucleus Accumbens by Dopamine and Cocaine
Wolf, M. E. (2010) · Springer eBooks · doi:10.1007/978-1-4614-0785-0_21 · Cited by 5
Li, X., Yan, J., Huang, S., Zhao, L., Wang, J., & Chen, Z.-Y. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.283457 · Cited by 5
Oh, J. H., Nam, T., & Choi, Y. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104112 · Cited by 5
Chu, C.-C., Hu, Y.-H., Li, G.-Z., Chen, J., Zhang, N.-N., Gu, Y., Wu, S., Zhang, H., Xu, Y.-Y., Guo, H.-L., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106812 · Cited by 4
Bauer, M. R., McVey, M. M., Zhang, Y.-P., & Boehm, S. L. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16555 · Cited by 4
Seyedi, F., Hedayati‐Moghadam, M., Heidari, M., Golkar, A., & Baghcheghi, Y. (2026) · NeuroToxicology · doi:10.1016/j.neuro.2026.103465 · Cited by 3
Lee, B., Xing, X., Hammes, E. A., Zeng, Z., Estrada‐Tobar, Z. M., Kim, K., Ireton, K. E., Man, K. N. M., Jacobi, A. A., Berumen, R. A., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116011 · Cited by 4
Postsynaptic Targeting of Protein Kinases and Phosphatases
Strack, S., & Hell, J. W. (2008) · Springer eBooks · doi:10.1007/978-0-387-77232-5_16 · Cited by 3
Spinal plasticity of the nociceptive system
Latrémolière, A. (2016) · Wiley eBooks · doi:10.1002/9781118455968.ch2 · Cited by 4
Shen, Y., Dai, Y., Yu, F. G., Peng, W., Liu, J., You, W., Luo, X., Ke, C., & Chen, N. (2024) · Environmental Research · doi:10.1016/j.envres.2024.120324 · Cited by 2
What's in your plate?AMPA receptors modulation at the crossroads of homeostatic and hedonic eating
Italia, M., Scheggia, D., Luca, M. D., & Gardoni, F. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107821 · Cited by 2
Making memories malleable: The role and regulation of synaptic depotentiation in engram alteration
Pauli, Q., & Bonin, R. P. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106481 · Cited by 2
The Impact of Electrographic Seizures on Developing Hippocampal Dendrites Is Calcineurin Dependent
Nishimura, M., Casanova, J. R., & Swann, J. W. (2017) · eNeuro · doi:10.1523/eneuro.0014-17.2017 · Cited by 2
General anesthetics as a factor of the effective neuroprotection in ischemic stroke models
Лалетин, В. С., & Bykov, Y. N. (2015) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s1990750815010059 · Cited by 2
Mao, L., & Wang, J. Q. (2020) · Brain and Behavior · doi:10.1002/brb3.1543 · Cited by 2
Hu, P., Maita, I., Kwok, C., Gu, E., Gergues, M. M., Liu, J., Pang, Z. P., Swaab, D. F., Lucassen, P. J., Roepke, T. A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/572966 · Cited by 2
Homeostasis of dendritic spines in hippocampal CA1 cells
Mestrallet, C. A. (2011) · UCL Discovery (University College London) · Cited by 2
Peterson, L. P., Nguyen, J., Ghani, N., Rodriguez-Echemendia, P., Qiao, H., Guwn, S. Y., Man, H., & Kantak, K. M. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1425447 · Cited by 1
Self-citationBeta 2-adrenergic pathway combats Alzheimer’s disease: Restoring cognition and synaptic integrity
Li, S., & Jin, S. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00529 · Cited by 3
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Costa, C., Bellingacci, L., Canonichesi, J., Imperatore, V., Taddei, A. A., Zafra‐Puerta, L., Iglesias‐Cabeza, N., Prontera, P., Mancini, A., Filippo, M. D., et al. (2025) · Epilepsia · doi:10.1111/epi.70024 · Cited by 1
Convergence and divergence of molecular mechanisms in Hebbian and homeostatic plasticity
Feighan, K. M., Thakare, H. K., Glasgow, S. D., & Kennedy, T. E. (2026) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2026.1761008 · Cited by 2
Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
Esteban, J. A. (2008) · Springer eBooks · doi:10.1007/978-0-387-77232-5_10 · Cited by 1
Modulation of the Core Neural Network in Stress: The Role of Endocannabinoids and LTD
Bennett, M. R., & Lagopoulos, J. (2018) · Springer eBooks · doi:10.1007/978-3-319-91116-8_5 · Cited by 1
Targeting AKAP79/150 in Human Disorders: An Emerging Opportunity for Future Therapies?
Chen, F., Chu, C.-C., Wu, C., Chen, F., Xu, J., Zhou, L., Fang, W. R., Lu, X., & Hu, Y. H. (2023) · Progress in Neurobiology · doi:10.60124/j.pneuro.2023.10.06
Mouse Medial-prefrontal Cortex Involvement in Trace Fear Memory during Wakefulness and Sleep
Steenland, H. W. (2011) · TSpace (University of Toronto) · Cited by 1
Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neuronsPreprint
Morales, C. O. O., Ignácz, A., Bencsik, N., Rátkai, A. E., Lieb, W. S., Eisler, S. A., Szűcs, A. L., Schlett, K., & Hausser, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.09.033514 · Cited by 1
Pauli, Q., Arsenault, J., Fung, S. W., Ramsey, A. J., & Bonin, R. P. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.28.640846 · Cited by 1
Park, E. (2008) · Rutgers University Community Repository (Rutgers University) · doi:10.7282/t31836v0
Luchkina, N. V. (2015) · Työväentutkimus Vuosikirja
Stress, emotional learning and AMPA receptors: from behavior to molecule
Mengyuan, Z. (2011) · UvA-DARE (University of Amsterdam)
Studies on antidepressant-mediated regulation of signal transduction
Qi, H. (2009) · Figshare
Role of AKAP5 in postsynaptic signaling complexes
Zhang, M. (2010) · doi:10.17077/etd.0caphnb1
Lee, A., Song, L., Kanold, P. O., Lee, H., Cayabyab, F. S., Chen, Z., Xiong, C., Pancyr, C., Stockwell, J., & Walz, W. (2015)
Pre- and Postsynaptic Assembly and Maturation
Sigrist, S. J., & Wichmann, C. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397266-8.00008-9
Mechanism underlying the maturation of AMPA receptors in zebrafish
Patten, S. A. (2009) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3jd0z
Exciting inhibition: Local regulation of synapse formation and plasticity
Kruijssen, D. L. H. (2020) · Utrecht University Repository (Utrecht University) · doi:10.33540/296
Dysfunction of EAAT3 Enhances LPS-Induced Postoperative Cognitive DysfunctionPreprint
Wang, X., Ma, Y., Hou, A., Song, Y., Sui, X., Liu, W., Liu, M., Wang, Y., Cao, J., & Mi, W. (2021) · Research Square · doi:10.21203/rs.3.rs-141076/v1
Dysfunction of EAAT3 Enhances LPS-induced Postoperative Cognitive DysfunctionPreprint
Wang, X., Ma, Y., Hou, A., Song, Y., Sui, X. Y., Liu, W., Liu, M., Wang, Y., Cao, J., & Mi, W. (2021) · Research Square · doi:10.21203/rs.3.rs-141076/v2
Effects of Different Stress Forms on Novel Object Recognition Memory Retrieval
梁, 凯. (2019) · Biophysics · doi:10.12677/jps.2019.74005
Dysfunction of EAAT3 enhances LPS-induced Postoperative Cognitive DysfunctionPreprint
Wang, X., Ma, Y., Hou, A., Song, Y., Sui, X. Y., Liu, W., Liu, M., Wang, Y., Cao, J., & Mi, W. (2021) · Research Square · doi:10.21203/rs.3.rs-141076/v3
Regulation of AMPA Receptor Trafficking in the Nucleus Accumbens by Dopamine and Cocaine
Wolf, M. E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7264-3_24
Dysfunction of EAAT3 Enhances LPS-induced Postoperative Cognitive DysfunctionPreprint
Wang, X., Ma, Y., Hou, A., Song, Y., Sui, X. Y., Liu, W., Liu, M., Wang, Y., Cao, J., & Mi, W. (2021) · doi:10.21203/rs.3.rs-169684/v1
Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
Esteban, J. A. (2008) · Research and perspectives in Alzheimer's disease · doi:10.1007/978-3-540-76330-7_2
Bauer, M. R., McVey, M. M., Zhang, Y.-P., & Boehm, S. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.15.585024
Guo, S., Zhao, Q., Zhang, L., Song, C., & Wang, G. (2025) · Indian Journal of Anaesthesia · doi:10.4103/ija.ija_1351_24
Zhang, Y., Weng, W., Liu, Y., Gao, J., Li, Y.-Z., Chu, C.-P., & Qiu, D. (2025) · Neuroreport · doi:10.1097/wnr.0000000000002205
Wang, Y., Tseng, H.-A., Xiao, S., Bortz, E., Zhou, Y., Martin, A., Man, H., Mertz, J. C., & Han, X. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.05.709685
Self-citation
Metadata
- Authors
- Man, H.-Y., Sekine-Aizawa, Y., & Huganir, R. L.
- Affiliations
- Howard Hughes Medical Institute (US)
- *Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205
- Corresponding author
- Huganir, Richard L.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2007-02-27
- Volume
- 104
- Issue
- 9
- Pages
- 3579-3584
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC1805611
- OpenAlex
- W2016126067
- Cited by
- 311
- References
- 24
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 11 · 2023: 16 · 2022: 8 · 2021: 20 · 2020: 13 · 2019: 13 · 2018: 19 · 2017: 12 · 2016: 17 · 2015: 22 · 2014: 17 · 2013: 21 · 2012: 16
- FWCI
- 9.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Howard Hughes Medical Institute
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Keywords
- AMPA receptors, GluA1 subunit, protein kinase A, receptor trafficking, receptor internalization, endocytosis, NMDA receptor, synaptic plasticity, excitatory synaptic transmission, cell surface expression
- MeSH terms
- Animals, Cerebral Cortex, Immunohistochemistry, Synaptic Transmission, Neurons, Phosphorylation, Protein Serine-Threonine Kinases, Cyclic AMP-Dependent Protein Kinases, Receptors, AMPA, Biotinylation, Protein Transport, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review