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Nanoprobes with near-infrared persistent luminescence for in vivo imaging
Open accessAbstract
Fluorescence is increasingly used for in vivo imaging and has provided remarkable results. Yet this technique presents several limitations, especially due to tissue autofluorescence under external illumination and weak tissue penetration of low wavelength excitation light. We have developed an alternative optical imaging technique by using persistent luminescent nanoparticles suitable for small animal imaging. These nanoparticles can be excited before injection, and their in vivo distribution can be followed in real-time for more than 1 h without the need for any external illumination source. Chemical modification of the nanoparticles' surface led to lung or liver targeting or to long-lasting blood circulation. Tumor mass could also be identified on a mouse model.
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A review of the optical properties of biological tissues
Cheong, W. F., Prahl, S. A., & Welch, A. J. (1990) · IEEE Journal of Quantum Electronics · doi:10.1109/3.64354 · Cited by 2,530
Cited by
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Pei, P., Chen, Y., Sun, C., Fan, Y., Yang, Y., Liu, X., Lu, L., Zhao, M., Zhang, H., Zhao, D., et al. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-00922-3 · Cited by 718
Ultralong Phosphorescence of Water‐Soluble Organic Nanoparticles for In Vivo Afterglow Imaging
Zhen, X., Tao, Y., An, Z., Chen, P., Xu, C., Chen, R., Huang, W., & Pu, K. (2017) · Advanced Materials · doi:10.1002/adma.201606665 · Cited by 602
Liu, F., Yan, W., Chuang, Y.-J., Zhen, Z., Xie, J., & Pan, Z. (2013) · Scientific Reports · doi:10.1038/srep01554 · Cited by 508
Tan, H., Wang, T., Shao, Y., Yu, C., & Hu, L. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00387 · Cited by 59
Chen, B., Zhang, X., Wang, Y., Miao, H., & Zhang, G. (2019) · Chemistry – An Asian Journal · doi:10.1002/asia.201801002 · Cited by 43
Metadata
- Authors
- le Masne de Chermont, Q., Chanéac, C., Seguin, J., Pellé, F., Maîtrejean, S., Jolivet, J.-P., Gourier, D., Bessodes, M., & Scherman, D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2007-05-29
- Volume
- 104
- Issue
- 22
- Pages
- 9266-9271
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2112823632
- Cited by
- 834
- References
- 1
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- green
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- le Masne de Chermont, Q., Chanéac, C., Seguin, J., Pellé, F., Maîtrejean, S., Jolivet, J.-P., Gourier, D., Bessodes, M., & Scherman, D. (2007). Nanoprobes with near-infrared persistent luminescence for in vivo imaging. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0702427104
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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