Arabidopsis fhl / fhy1 double mutant reveals a distinct cytoplasmic action of phytochrome A
Open accessAbstract
Phytochrome A (phyA) plays an important role during germination and early seedling development. Because phyA is the primary photoreceptor for the high-irradiance response and the very-low-fluence response, it can trigger development not only in red and far-red (FR) light but also in a wider range of light qualities. Although phyA action is generally associated with translocation to the nucleus and regulation of transcription, there is evidence for additional cytoplasmic functions. Because nuclear accumulation of phyA has been shown to depend on far-red-elongated hypocotyl 1 (FHY1) and FHL (FHY1-like), investigation of phyA function in a double fhl/fhy1 mutant might be valuable in revealing the mechanism of phyA translocation and possible cytoplasmic functions. In fhl/fhy1 , the FR-triggered nuclear translocation of phyA could no longer be detected but could be restored by transgenic expression of CFP:FHY1 . Whereas the fhl/fhy1 mutant showed a phyA phenotype in respect to hypocotyl elongation and cotyledon opening under high-irradiance response conditions as well as a typical phyA germination phenotype under very-low-fluence response conditions, fhl/fhy1 showed no phenotype with respect to the phyA-dependent abrogation of negative gravitropism in blue light and in red-enhanced phototropism, demonstrating clear cytoplasmic functions of phyA. Disturbance of phyA nuclear import in fhl/fhy1 led to formation of FR-induced phyA:GFP cytoplasmic foci resembling the sequestered areas of phytochrome. FHY1 and FHL play crucial roles in phyA nuclear translocation and signaling. Thus the double-mutant fhl/fhy1 allows nuclear and cytoplasmic phyA functions to be separated, leading to the novel identification of cytoplasmic phyA responses.
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Red light-activated phytochromes can inhibit blue light-induced migration of PHOT1 to the cytoplasm.
“Red light-activated phytochromes can inhibit blue light-induced migration of PHOT1 to the cytoplasm. (Rosler et al., 2007; Han et al., 2008).”
From The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants (2022) · cites this paper as Rosler et al., 2007
The Results describe red-light-enhanced phototropism, and the Discussion says PHOT1 and phyA may be linked through PKS1. Neither passage addresses whether red-light-activated phytochromes inhibit blue-light-induced PHOT1 migration to the cytoplasm. Searches for PHOT1 migration and translocation found no passage establishing that effect. (LLM, conf=0.73)
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HY4 gene of A. thaliana encodes a protein with characteristics of a blue-light photoreceptor
Ahmad, M., & Cashmore, A. R. (1993) · Nature · doi:10.1038/366162a0 · Cited by 1,270 · see citing works
Reed, J. W., Nagpal, P., Poole, D. S., Furuya, M., & Chory, J. (1993) · The Plant Cell · doi:10.1105/tpc.5.2.147 · Cited by 957 · see citing works
Signal Transduction in Maize and Arabidopsis Mesophyll Protoplasts
Sheen, J. (2001) · PLANT PHYSIOLOGY · doi:10.1104/pp.010820 · Cited by 693 · see citing works
Clack, T., Mathews, S., & Sharrock, R. (1994) · Plant Molecular Biology · doi:10.1007/bf00043870 · Cited by 678 · see citing works
Deng, X., Caspar, T., & Quail, P. H. (1991) · Genes & Development · doi:10.1101/gad.5.7.1172 · Cited by 564 · see citing works
Shinomura, T., Nagatani, A., Hanzawa, H., Kubota, M., Watanabe, M., & Furuya, M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.8129 · Cited by 549 · see citing works
Phytochrome A null mutants of Arabidopsis display a wild-type phenotype in white light.
Whitelam, G. C., Johnson, E., Peng, J., Carol, P., Anderson, M. L., Cowl, J. S., & Harberd, N. P. (1993) · The Plant Cell · doi:10.1105/tpc.5.7.757 · Cited by 535 · see citing works
Lin, C., Yang, H., Guo, H., Mockler, T. C., Chen, J., & Cashmore, A. R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2686 · Cited by 519 · see citing works
Functional selectivity of recombinant mammalian SWI/SNF subunitsPreprint
Kadam, S., McAlpine, G. S., Phelan, M. L., Kingston, R. E., Jones, K. A., & Emerson, B. M. (2000) · Genes & Development · doi:10.1101/gad.828000 · Cited by 497 · see citing works
Multiple transcription-factor genes are early targets of phytochrome A signaling
Tepperman, J. M., Zhu, T., Chang, H., Wang, X., & Quail, P. H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.161300998 · Cited by 481 · see citing works
Isolation and Initial Characterization of Arabidopsis Mutants That Are Deficient in Phytochrome A
Nagatani, A., Reed, J. W., & Chory, J. (1993) · PLANT PHYSIOLOGY · doi:10.1104/pp.102.1.269 · Cited by 463 · see citing works
Light Quality–Dependent Nuclear Import of the Plant Photoreceptors Phytochrome A and B
Kircher, S., Kozma‐Bognár, L., Kim, L., Ádám, É., Harter, K., Schäfer, E., & Nagy, F. (1999) · The Plant Cell · doi:10.1105/tpc.11.8.1445 · Cited by 396 · see citing works
The CRY1 Blue Light Photoreceptor of Arabidopsis Interacts with Phytochrome A In Vitro
Ahmad, M., Jarillo, J. A., Smirnova, O., & Cashmore, A. R. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80094-5 · Cited by 312 · see citing works
Dimers of the N-terminal domain of phytochrome B are functional in the nucleus
Matsushita, T., Mochizuki, N., & Nagatani, A. (2003) · Nature · doi:10.1038/nature01837 · Cited by 308 · see citing works
Patterns of Expression and Normalized Levels of the Five Arabidopsis Phytochromes
Sharrock, R., & Clack, T. (2002) · PLANT PHYSIOLOGY · doi:10.1104/pp.005389 · Cited by 295 · see citing works
Phytochrome signalling is mediated through nucleoside diphosphate kinase 2
Choi, G., Yi, H., Lee, J., Kwon, Y., Soh, M., Shin, B., Luka, Z., Hahn, T., & Song, P.-S. (1999) · Nature · doi:10.1038/44176 · Cited by 290 · see citing works
Shinomura, T., Uchida, K., & Furuya, M. (2000) · PLANT PHYSIOLOGY · doi:10.1104/pp.122.1.147 · Cited by 197 · see citing works
FHY1 and FHL Act Together to Mediate Nuclear Accumulation of the Phytochrome A Photoreceptor
Hiltbrunner, A., Tscheuschler, A., Viczián, A., Kunkel, T., Kircher, S., & Schäfer, E. (2006) · Plant and Cell Physiology · doi:10.1093/pcp/pcj087 · Cited by 192 · see citing works
PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism
Lariguet, P., Schepens, I., Hodgson, D., Pedmale, U. V., Trevisan, M., Kami, C., de Carbonnel, M., Alonso, J. M., Ecker, J. R., Liscum, E., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603799103 · Cited by 190 · see citing works
Phytochrome Control of Two Low-Irradiance Responses in Etiolated Oat Seedlings
Mandoli, D. F., & Briggs, W. R. (1981) · PLANT PHYSIOLOGY · doi:10.1104/pp.67.4.733 · Cited by 176 · see citing works
Nuclear Accumulation of the Phytochrome A Photoreceptor Requires FHY1
Hiltbrunner, A., Viczián, A., Bury, E., Tscheuschler, A., Kircher, S., Tóth, R., Honsberger, A., Nagy, F., Fankhauser, C., & Schäfer, E. (2005) · Current Biology · doi:10.1016/j.cub.2005.10.042 · Cited by 168 · see citing works
HFR1, a putative bHLH transcription factor, mediates both phytochrome A and cryptochrome signalling
Duek, P. D., & Fankhauser, C. (2003) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01770.x · Cited by 167 · see citing works
Photocontrol of Anthocyanin Formation in Turnip and Red Cabbage Seedlings.
Siegelman, H. W., & Hendricks, S. B. (1957) · PLANT PHYSIOLOGY · doi:10.1104/pp.32.5.393 · Cited by 159 · see citing works
SUB1, an Arabidopsis Ca 2+ -Binding Protein Involved in Cryptochrome and Phytochrome Coaction
Guo, H., Mockler, T. C., Duong, H., & Lin, C. (2001) · Science · doi:10.1126/science.291.5503.487 · Cited by 136 · see citing works
A RAPID PHOTOREVERSIBLE RESPONSE OF BARLEY ROOT TIPS IN THE PRESENCE OF 3-INDOLEACETIC ACID
Tanada, T. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.59.2.376 · Cited by 127 · see citing works
Kim, L., Kircher, S., Tóth, R., Ádám, É., Schäfer, E., & Nagy, F. (2000) · The Plant Journal · doi:10.1046/j.1365-313x.2000.00729.x · Cited by 125 · see citing works
Lariguet, P., & Fankhauser, C. (2004) · The Plant Journal · doi:10.1111/j.1365-313x.2004.02256.x · Cited by 103 · see citing works
FHY1: a phytochrome A-specific signal transducerPreprint
Desnos, T., Puente, P., Whitelam, G. C., & Harberd, N. P. (2001) · Genes & Development · doi:10.1101/gad.205401 · Cited by 95 · see citing works
Mackenzie, J., Coleman, R. A., Briggs, W. R., & Pratt, L. H. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.3.799 · Cited by 92 · see citing works
Robson, P. R. H., & SMITH, H. (1996) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.1.211 · Cited by 91 · see citing works
FHL is required for full phytochrome A signaling and shares overlapping functions with FHY1
Zhou, Q., Hare, P. D., Yang, S. W., Zeidler, M., Huang, L., & Chua, N. (2005) · The Plant Journal · doi:10.1111/j.1365-313x.2005.02453.x · Cited by 85 · see citing works
Self-citationEffect of Red Light on the Phototropic Sensitivity of Corn Coleoptiles
Chon, H. P., & Briggs, W. R. (1966) · PLANT PHYSIOLOGY · doi:10.1104/pp.41.10.1715 · Cited by 85 · see citing works
Phytochrome-mediated light signalling in Arabidopsis
Schepens, I., Duek, P. D., & Fankhauser, C. (2004) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2004.07.004 · Cited by 83 · see citing works
Targeted knockout in Physcomitrella reveals direct actions of phytochrome in the cytoplasm
Mittmann, F., Brücker, G., Zeidler, M., Repp, A., Abts, T., Hartmann, E., & Hughes, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403140101 · Cited by 82 · see citing works
Self-citationStowe-Evans, E. L., Luesse, D. R., & Emmanuel Liscum, A. (2001) · PLANT PHYSIOLOGY · doi:10.1104/pp.126.2.826 · Cited by 77 · see citing works
Phytochrome-mediated Electric Potential Changes in Oat Seedlings
Newman, I. A., & Briggs, W. R. (1972) · PLANT PHYSIOLOGY · doi:10.1104/pp.50.6.687 · Cited by 75 · see citing works
Poppe, C., Hangarter, R. P., Sharrock, R., Nagy, F., & Sch�fer, E. (1996) · Planta · doi:10.1007/bf00195180 · Cited by 62 · see citing works
Emmanuel Liscum, A., & Stowe-Evans, E. L. (2000) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2000)0720273pasprm2.0.co2 · Cited by 52 · see citing works
Krieg (2000) · Pure Amsterdam UMC · doi:10.1562/0031-8655(2000)072 · Cited by 50 · see citing works
Casal, J. J., Yanovsky, M. J., & Luppi, J. P. (2000) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2000)0710481tppopa2.0.co2 · Cited by 46 · see citing works
Zeidler, M., Zhou, Q., Sarda, X., Yau, C. B. K., & Chua, N. (2004) · The Plant Journal · doi:10.1111/j.1365-313x.2004.02212.x · Cited by 43 · see citing works
Self-citationIrradiation-enhanced Phytochrome Pelletability
Quail, P. H., & Briggs, W. R. (1978) · PLANT PHYSIOLOGY · doi:10.1104/pp.62.5.773 · Cited by 38 · see citing works
McCurdy, D. W., & Pratt, L. H. (1986) · Planta · doi:10.1007/bf00391335 · Cited by 38 · see citing works
Takagi, S., Kong, S., Mineyuki, Y., & Furuya, M. (2003) · The Plant Cell · doi:10.1105/tpc.007237 · Cited by 35 · see citing works
Phytochrome A: functional diversity and polymorphism
Sineshchekov, V. A. (2004) · Photochemical & Photobiological Sciences · doi:10.1039/b315430k · Cited by 31 · see citing works
Zeidler, M., Bolle, C., & Chua, N. (2001) · Plant and Cell Physiology · doi:10.1093/pcp/pce177 · Cited by 29 · see citing works
Self-citationAllen, T., Ingles, P. J., Praekelt, U. M., Smith, H., & Whitelam, G. C. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2006.02727.x · Cited by 25 · see citing works
Bernerd (2000) · doi:10.1562/0031-8655(2000)071 · Cited by 18 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- [25]Fairchild CD, Schumaker MA, Quail PH. Genes Dev. 2000;14:2377–2391. [PMC free article] [PubMed] [Google Scholar]
- [31]Quail PH. In: Encyclopedia of Plant Physiol. Shropshire W Jr, Mohr H, editors. Vol 16. Heidelberg: Springer; 1983. pp. 178–212. Book A. [Google Scholar]
- [47]Sheen J. Plant Physiol. 2001;127:1466–1475. [PMC free article] [PubMed] [Google Scholar]
- [48]Sambrook J, Russel D, editors. Molecular Cloning: A Laboratory Manual. Plainview, NY: Cold Spring Harbor Lab Press; 2001. p. A9.28. [Google Scholar]
Cited by
Sorted by citations
Light-Regulated Plant Growth and Development
Kami, C., Lorrain, S., Hornitschek, P., & Fankhauser, C. (2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)91002-8 · Cited by 927 · see citing works
Hornitschek, P., Kohnen, M. V., Lorrain, S., Rougemont, J., Ljung, K., López‐Vidriero, I., Franco‐Zorrilla, J. M., Solano, R., Trévisan, M., Pradervand, S., et al. (2012) · The Plant Journal · doi:10.1111/j.1365-313x.2012.05033.x · Cited by 603 · see citing works
Phytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Deng, X. W. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 566 · see citing works
Phytochrome Interacting Factors: central players in phytochrome-mediated light signaling networks
Castillon, A., Shen, H., & Huq, E. (2007) · Trends in Plant Science · doi:10.1016/j.tplants.2007.10.001 · Cited by 470 · see citing works
Phytochrome signaling mechanisms and the control of plant development
Chen, M., & Chory, J. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.07.002 · Cited by 450 · see citing works
Shen, H., Zhu, L. Q., Castillon, A., Majee, M., Downie, A. B., & Huq, E. (2008) · The Plant Cell · doi:10.1105/tpc.108.060020 · Cited by 294 · see citing works
Arabidopsis HEMERA/pTAC12 Initiates Photomorphogenesis by Phytochromes
Chen, M., Galvão, R. M., Li, M., Burger, B. T., Bugea, J., Bolado, J., & Chory, J. (2010) · Cell · doi:10.1016/j.cell.2010.05.007 · Cited by 264 · see citing works
Fungi, Hidden in Soil or Up in the Air: Light Makes a Difference
Rodríguez‐Romero, J., Hedtke, M., Kästner, C., Müller, S., & Fischer, R. (2010) · Annual Review of Microbiology · doi:10.1146/annurev.micro.112408.134000 · Cited by 256 · see citing works
Phototropism: Growing towards an Understanding of Plant Movement
Liscum, E., Askinosie, S. K., Leuchtman, D. L., Morrow, J., Willenburg, K. T., & Coats, D. R. (2014) · The Plant Cell · doi:10.1105/tpc.113.119727 · Cited by 215 · see citing works
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Xu, X., Paik, I., Zhu, L. Q., & Huq, E. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2015.06.010 · Cited by 216 · see citing works
Li, J., Li, G., Gao, S., Martínez, C., He, G., Zhou, Z., Huang, X. X., Lee, J., Zhang, H., Shen, Y., et al. (2010) · The Plant Cell · doi:10.1105/tpc.110.075788 · Cited by 186 · see citing works
Rausenberger, J., Tscheuschler, A., Nordmeier, W., Wüst, F., Timmer, J., Schäfer, E., Fleck, C. C., & Hiltbrunner, A. (2011) · Cell · doi:10.1016/j.cell.2011.07.023 · Cited by 176 · see citing works
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Casal, J. J., Candia, A. J. N., & Sellaro, R. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ert379 · Cited by 135 · see citing works
FHY1 Mediates Nuclear Import of the Light-Activated Phytochrome A Photoreceptor
Genoud, T., Schweizer, F., Tscheuschler, A., Debrieux, D., Casal, J. J., Schäfer, E., Hiltbrunner, A., & Fankhauser, C. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000143 · Cited by 127 · see citing works
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Ma, L., Han, R., Yang, Y., Liu, X., Li, H., Zhao, X., Li, J., Fu, H., Huo, Y., Sun, L., et al. (2023) · The Plant Cell · doi:10.1093/plcell/koad117 · Cited by 106 · see citing works
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Hughes, J. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050312-120045 · Cited by 104 · see citing works
A phytochrome–phototropin light signaling complex at the plasma membrane
Jaedicke, K., Lichtenthäler, A. L., Meyberg, R., Zeidler, M., & Hughes, J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120203109 · Cited by 102 · see citing works
Self-citationYang, S. W., Jang, I., Henriques, R., & Chua, N. (2009) · The Plant Cell · doi:10.1105/tpc.109.067215 · Cited by 92 · see citing works
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Hohm, T., Preuten, T., & Fankhauser, C. (2012) · American Journal of Botany · doi:10.3732/ajb.1200299 · Cited by 91 · see citing works
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Pfeiffer, A., Nagel, M.-K., Popp, C., Wüst, F., Bindics, J., Viczián, A., Hiltbrunner, A., Nagy, F., Kunkel, T., & Schäfer, E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120764109 · Cited by 88 · see citing works
Stephenson, P. G., & Terry, M. J. (2008) · Photochemical & Photobiological Sciences · doi:10.1039/b802596g · Cited by 83 · see citing works
Phytochrome regulates translation of mRNA in the cytosol
Paik, I., Yang, S., & Choi, G. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1109683109 · Cited by 81 · see citing works
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Possart, A., Fleck, C. C., & Hiltbrunner, A. (2013) · Plant Science · doi:10.1016/j.plantsci.2013.11.013 · Cited by 73 · see citing works
Scherer, G. F. E. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err033 · Cited by 69 · see citing works
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Voitsekhovskaja, O. V. (2019) · Russian Journal of Plant Physiology · doi:10.1134/s1021443719030154 · Cited by 67 · see citing works
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Possart, A., & Hiltbrunner, A. (2013) · The Plant Cell · doi:10.1105/tpc.112.104331 · Cited by 65 · see citing works
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Zhang, S., Li, C., Zhou, Y., Wang, X., Li, H., Feng, Z., Chen, H., Qin, G., Jin, D., Terzaghi, W., et al. (2018) · The Plant Cell · doi:10.1105/tpc.17.00677 · Cited by 60 · see citing works
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Kami, C., Hersch, M., Trevisan, M., Genoud, T., Hiltbrunner, A., Bergmann, S., & Fankhauser, C. (2012) · The Plant Cell · doi:10.1105/tpc.111.095083 · Cited by 55 · see citing works
Song, C., Mroginski, M. A., Lang, C., Kopycki, J., Gärtner, W., Matysik, J., & Hughes, J. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.00498 · Cited by 51 · see citing works
Jang, I., Henriques, R., & Chua, N. (2013) · Plant and Cell Physiology · doi:10.1093/pcp/pct042 · Cited by 49 · see citing works
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Molas, M. L., & Kiss, J. Z. (2009) · Advances in botanical research · doi:10.1016/s0065-2296(08)00601-0 · Cited by 49 · see citing works
Castillon, A., Shen, H., & Huq, E. (2009) · Genetics · doi:10.1534/genetics.108.099887 · Cited by 48 · see citing works
Light‐induced modification of plant plasma membrane ion transport
Marten, I., Deeken, R., Hedrich, R., & Roelfsema, M. R. G. (2010) · Plant Biology · doi:10.1111/j.1438-8677.2010.00384.x · Cited by 46 · see citing works
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Hoang, Q. T. N., Han, Y., & Kim, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143450 · Cited by 44 · see citing works
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Self-citationLi, J., Ezquer, I., Bahaji, A., Montero, M., Ovečka, M., Baroja‐Fernández, E., Muñoz, F. J., Mérida, Á., Almagro, G., Hidalgo, M., et al. (2011) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-05-11-0112 · Cited by 42 · see citing works
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Zhou, Y., Yang, L., Duan, J., Cheng, J., Shen, Y., Wang, X., Han, R., Li, H., Li, Z., Wang, L., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1813162115 · Cited by 41 · see citing works
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Wei, Q., Zhou, W., Hu, G., Wei, J., Yang, H., & Huang, J. (2008) · Cell Research · doi:10.1038/cr.2008.271 · Cited by 39 · see citing works
Preuten, T., Blackwood, L., Christie, J. M., & Fankhauser, C. (2015) · New Phytologist · doi:10.1111/nph.13299 · Cited by 38 · see citing works
Warnasooriya, S., & Montgomery, B. L. (2008) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.127050 · Cited by 38 · see citing works
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Debrieux, D., & Fankhauser, C. (2010) · Plant Molecular Biology · doi:10.1007/s11103-010-9649-9 · Cited by 38 · see citing works
Santin, M., Ranieri, A., & Castagna, A. (2021) · Plants · doi:10.3390/plants10071485 · Cited by 34 · see citing works
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Toledo‐Ortiz, G., Kiriu, Y., Kobayashi, J., Oka, Y., Kim, Y., Nam, H. G., Mochizuki, N., & Nagatani, A. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq121 · Cited by 33 · see citing works
A cell‐free system for light‐dependent nuclear import of phytochrome
Pfeiffer, A., Kunkel, T., Hiltbrunner, A., Neuhaus, G., Wolf, I., Speth, V., Ádám, É., Nagy, F., & Schäfer, E. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03721.x · Cited by 33 · see citing works
Wilson, R. L., Bakshi, A., & Binder, B. M. (2014) · Frontiers in Plant Science · doi:10.3389/fpls.2014.00433 · Cited by 33 · see citing works
The Arabidopsis Nuclear Pore and Nuclear Envelope
Meier, I., & Brkljačić, J. M. (2010) · The Arabidopsis Book · doi:10.1199/tab.0139 · Cited by 31 · see citing works
Helizon, H., Dalton‐Roesler, J., Gasch, P., von Horsten, S., Essen, L., & Zeidler, M. (2018) · The Plant Journal · doi:10.1111/tpj.14107 · Cited by 31 · see citing works
Self-citationPhytochrome A Mediates Blue-Light Enhancement of Second-Positive Phototropism in Arabidopsis
Sullivan, S., Hart, J. E., Rasch, P., Walker, C. H., & Christie, J. M. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00290 · Cited by 29 · see citing works
Shin, D. H., Cho, M.-H., Kim, T., Yoo, J., Kim, J., Han, Y., Song, P., Jeon, J., Bhoo, S. H., & Hahn, T. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.133710 · Cited by 28 · see citing works
Viczián, A., Ádám, É., Wolf, I., Bindics, J., Kircher, S., Heijde, M., Ulm, R., Schäfer, E., & Nagy, F. (2012) · Molecular Plant · doi:10.1093/mp/sss035 · Cited by 27 · see citing works
OWL1: An Arabidopsis J-Domain Protein Involved in Perception of Very Low Light Fluences
Kneißl, J., Wachtler, V., Chua, N., & Bolle, C. (2009) · The Plant Cell · doi:10.1105/tpc.109.066472 · Cited by 26 · see citing works
Montgomery, B. L. (2008) · Plant Signaling & Behavior · doi:10.4161/psb.3.12.6857 · Cited by 26 · see citing works
Molecular Evolution and Interaction of Membrane Transport and Photoreception in Plants
Babla, M. H., Cai, S., Chen, G. J., Tissue, D. T., Cazzonelli, C. I., & Chen, Z. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00956 · Cited by 24 · see citing works
New Constitutively Active Phytochromes Exhibit Light-Independent Signaling Activity
Jeong, A., Lee, S.-S., Han, Y., Shin, A.-Y., Baek, A., Ahn, T., Kim, M., Kim, Y. S., Lee, K. W., Nagatani, A., et al. (2016) · PLANT PHYSIOLOGY · doi:10.1104/pp.16.00342 · Cited by 23 · see citing works
Light-Regulated Nuclear Import and Degradation of Arabidopsis Phytochrome-A N-Terminal Fragments
Wolf, I., Kircher, S., Fejes, E., Kozma‐Bognár, L., Schäfer, E., Nagy, F., & Ádám, É. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq194 · Cited by 23 · see citing works
Shah, A., Tyagi, S., Saratale, G. D., Guzik, U., Hu, A., Sreevathsa, R., Reddy, V. D., Rai, V., & Mulla, S. I. (2021) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2020.1869686 · Cited by 22 · see citing works
Oka, Y., Ono, Y., Toledo‐Ortiz, G., Kokaji, K., Matsui, M., Mochizuki, N., & Nagatani, A. (2012) · The Plant Cell · doi:10.1105/tpc.111.094201 · Cited by 22 · see citing works
Chang, G., Xiang, F., Fan, Y., Jiang, L., & Zhong, S. (2025) · New Phytologist · doi:10.1111/nph.70572 · Cited by 21 · see citing works
Galstyan, A., Bou‐Torrent, J., Roig‐Villanova, I., & Martínez‐García, J. F. (2012) · Molecular Plant · doi:10.1093/mp/sss006 · Cited by 21 · see citing works
Arabidopsis FHY1 and FHY1-LIKE Are Not Required for Phytochrome A Signal Transduction in the Nucleus
Menon, C., Klose, C., & Hiltbrunner, A. (2019) · Plant Communications · doi:10.1016/j.xplc.2019.100007 · Cited by 19 · see citing works
Mutants of phospholipase A ( pPLA ‐ I ) have a red light and auxin phenotype
Effendi, Y., RADATZ, K., Labusch, C., Rietz, S., Wimalasekera, R., Helizon, H., Zeidler, M., & Scherer, G. F. E. (2014) · Plant Cell & Environment · doi:10.1111/pce.12278 · Cited by 19 · see citing works
Self-citationMüller, R., Fernández, A. P., Hiltbrunner, A., Schäfer, E., & Kretsch, T. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.135988 · Cited by 19 · see citing works
The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants
Xin, G.-Y., Li, L.-P., Wang, P.-T., Li, X.-Y., Han, Y.-J., & Zhao, X. (2022) · Stress Biology · doi:10.1007/s44154-022-00066-x · Cited by 17 · see citing works
Bao, Q., Mu, X., Chen, T., Li, C., Tao, W.-Z., Zhao, S.-T., Liu, Y.-X., Wang, W.-N., Wei, Y.-T., Yu, F.-H., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2302854120 · Cited by 16 · see citing works
Sineshchekov, V. A., Koppel, L. A., Shor, E., Кочетова, Г. В., Galland, P., & Zeidler, M. (2012) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2012.01226.x · Cited by 15 · see citing works
Self-citationThe role of the COP1, SPA, and PIF proteins in plant photomorphogenesis
Смирнова, О. Г., Stepanenko, I. L., & Константинович, Ш. В. (2011) · Biology Bulletin Reviews · doi:10.1134/s2079086411040098 · Cited by 14 · see citing works
Phytochrome A-specific signaling inArabidopsis thaliana
Kircher, S., Terecskei, K., Wolf, I., Sipos, M., & Ádám, É. (2011) · Plant Signaling & Behavior · doi:10.4161/psb.6.11.17509 · Cited by 14 · see citing works
Multiple Dimensions in Plant Signal Transduction: An Overview
Casal, J. J. (2008) · Methods in molecular biology · doi:10.1007/978-1-59745-289-2_1 · Cited by 14 · see citing works
Nuclear Phytochrome B Regulates Leaf Flattening through Phytochrome Interacting Factors
Johansson, H., & Hughes, J. (2014) · Molecular Plant · doi:10.1093/mp/ssu077 · Cited by 13 · see citing works
Protein Kinase Activity of Phytochrome A Positively Correlates With Photoresponses in Arabidopsis
Hoang, Q. T. N., Cho, J., Choi, D., Shin, A.-Y., Kim, J. A., Han, Y., & Kim, J. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.706316 · Cited by 13 · see citing works
Sokolova, V., Bindics, J., Kircher, S., Ádám, É., Schäfer, E., Nagy, F., & Viczián, A. (2011) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.186288 · Cited by 12 · see citing works
Arabidopsis Circadian Clock Repress Phytochrome a Signaling
Liu, Y., Sun, Y., Yao, H., Zheng, Y., Cao, S., & Wang, H. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.809563 · Cited by 12 · see citing works
Sineshchekov, V. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098139 · Cited by 11 · see citing works
Photomorphogenesis and Photoperiodism in Plants
Weller, J. L., & Kendrick, R. E. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1468-5_19 · Cited by 11 · see citing works
JA modulates phytochrome a signaling via repressing FHY3 activity by JAZ proteins
Liu, Y., & Wang, H. (2020) · Plant Signaling & Behavior · doi:10.1080/15592324.2020.1726636 · Cited by 10 · see citing works
Directed dimerization: an in vivo expression system for functional studies of type II phytochromes
Liu, P., & Sharrock, R. (2013) · The Plant Journal · doi:10.1111/tpj.12255 · Cited by 10 · see citing works
SUMOylation of different targets fine‐tunes phytochrome signaling
Péter, C., Nagy, F., & Viczián, A. (2021) · New Phytologist · doi:10.1111/nph.17634 · Cited by 9 · see citing works
Gong, F., Cao, D., Qu, C., Yin, D., Zhao, Q., & Xiong, E. (2021) · Journal of Plant Interactions · doi:10.1080/17429145.2021.1998681 · Cited by 9 · see citing works
Sineshchekov, V. A., Sudnitsin, A., Ádám, É., Schäfer, E., & Viczián, A. (2014) · Photochemical & Photobiological Sciences · doi:10.1039/c4pp00220b · Cited by 9 · see citing works
Ermert, A. L., Mailliet, K., & Hughes, J. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00613 · Cited by 7 · see citing works
Signaling Cross Talk Under the Control of Plant Photoreceptors
Jiang, L., & Li, S. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1468-5_14 · Cited by 7 · see citing works
Jiang, H.-W., Peng, K.-C., Hsu, T.-Y., Chiou, Y.-C., & Hsieh, H.-L. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010779 · Cited by 6 · see citing works
Park, H. L., Cho, M.-H., Shin, D. H., Bhoo, S. H., & Hahn, T. (2012) · Journal of the Korean Society for Applied Biological Chemistry · doi:10.1007/s13765-012-1159-9 · Cited by 6 · see citing works
Sineshchekov, V. A., & Koppel, L. A. (2022) · Biophysical Reviews · doi:10.1007/s12551-022-00974-2 · Cited by 6 · see citing works
Phototropism in land plants: Molecules and mechanism from light perception to response
Morrow, J., Willenburg, K. T., & Emmanuel Liscum, A. (2018) · Frontiers in Biology · doi:10.1007/s11515-018-1518-y · Cited by 6 · see citing works
Co-Sintering of Dense YSZ Electrolyte Films on Porous NiO-YSZ Supporting Anodes for IT-SOFCs
Savo, G. (2005) · ECS Proceedings Volumes · doi:10.1149/200507.1031pv · Cited by 4 · see citing works
Design and Characterization of a Stand-Alone Merging Unit
Cipolletta, G., Femine, A. D., Gallo, D., Landi, C., & Luiso, M. (2020) · ACTA IMEKO · doi:10.21014/acta_imeko.v9i1.753 · Cited by 3 · see citing works
Fine-Tuning by the Touch of Big Dudes: SUMOs Role in Light Signaling
Zeidler, M. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.06.001 · Cited by 3 · see citing works
Self-citationLight Sensing at the Plasma Membrane
Christie, J. M., Kaiserli, E., & Sullivan, S. (2010) · Plant cell monographs · doi:10.1007/978-3-642-13431-9_19 · Cited by 2 · see citing works
Physiological Analysis of Phototropic Responses to Blue and Red Light in Arabidopsis
Zeidler, M. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2297-1_4 · Cited by 2 · see citing works
Self-citationPhysiological Analysis of Phototropic Responses in Arabidopsis
Zeidler, M. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3356-3_3 · Cited by 2 · see citing works
Self-citationAnalysis of Phytochrome-Dependent Seed Germination in Arabidopsis
Zeidler, M. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2297-1_8 · Cited by 1 · see citing works
Self-citationSineshchekov, V. A., & Koppel, L. A. (2025) · PROTOPLASMA · doi:10.1007/s00709-025-02078-6 · Cited by 1 · see citing works
Huo, C., Liu, Y., Feng, X., Jin, H., & Zhu, P. (2025) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2025.110622 · Cited by 1 · see citing works
PHYTOCHROME INTERACTING FACTOR 7 moderates the activity of phytochrome A in canopy shade conditionsPreprint
Zhou, M., Romanowski, A., & Halliday, K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.07.680213 · Cited by 1 · see citing works
- Authors
- Rösler, J., Klein, I., & Zeidler, M.
- Affiliations
- Justus-Liebig-Universität Gießen (DE)
- Carnegie Institution for Science (US)
- Corresponding author
- Zeidler, Mathias
- ORCID
- Zeidler, Mathias
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2007-06-19
- Volume
- 104
- Issue
- 25
- Pages
- 10737-10742
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC1965582
- OpenAlex
- W2096295687
- Cited by
- 114
- References
- 47
- Citations by year
- 2026: 3 · 2025: 7 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 3 · 2019: 4 · 2018: 7 · 2017: 1 · 2016: 4 · 2015: 3 · 2014: 10 · 2013: 8 · 2012: 13
- FWCI
- 10.94
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Keywords
- phytochrome A, nuclear translocation, far-red light, high irradiance response, hypocotyl elongation, cotyledon opening, gravitropism, phototropism, Arabidopsis thaliana, double mutants
- MeSH terms
- Cytoplasm, Mutation, Recombinant Fusion Proteins, Arabidopsis, Hypocotyl, Transgenes, Arabidopsis Proteins, Plants, Genetically Modified, Green Fluorescent Proteins, Phytochrome A
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