Cited by 398Neurobiology of Language and BilingualismTranscranial Magnetic Stimulation StudiesDementia and Cognitive Impairment Research

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Anterior temporal lobes mediate semantic representation: Mimicking semantic dementia by using rTMS in normal participants

Open access

Pobric, Gorana, Jefferies, Elizabeth, Ralph, Matthew A. Lambon·2007·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.0707383104PMC PMC2148435

Open this paper in CoChat — free account

Abstract

Studies of semantic dementia and PET neuroimaging investigations suggest that the anterior temporal lobes (ATL) are a critical substrate for semantic representation. In stark contrast, classical neurological models of comprehension do not include ATL, and likewise functional MRI studies often fail to show activations in the ATL, reinforcing the classical view. Using a novel application of low-frequency, repetitive transcranial magnetic stimulation (rTMS) over the ATL, we demonstrate that the behavioral pattern of semantic dementia can be mirrored in neurologically intact participants: Specifically, we show that temporary disruption to neural processing in the ATL produces a selective semantic impairment leading to significant slowing in both picture naming and word comprehension but not to other equally demanding, nonsemantic cognitive tasks.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1073/pnas.0707383104

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
A standardized set of 260 pictures: Norms for name agreement, image agreement, familiarity, and visual complexity.
Snodgrass, J. G., & Vanderwart, M. (1980) · Journal of Experimental Psychology Human Learning & Memory · doi:10.1037//0278-7393.6.2.174 · Cited by 5,604
The cortical organization of speech processing
Hickok, G., & Poeppel, D. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2113 · Cited by 5,495
Role of left inferior prefrontal cortex in retrieval of semantic knowledge: A reevaluation
Thompson‐Schill, S. L., D’Esposito, M., Aguirre, G. K., & Farah, M. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14792 · Cited by 2,137
SEMANTIC DEMENTIA: PROGRESSIVE FLUENT APHASIA WITH TEMPORAL LOBE ATROPHY
HODGES, J. R., PATTERSON, K., OXBURY, S., & FUNNELL, E. (1992) · Brain · doi:10.1093/brain/115.6.1783 · Cited by 1,710
The Representation of Object Concepts in the Brain
Martin, A. D. (2006) · Annual Review of Psychology · doi:10.1146/annurev.psych.57.102904.190143 · Cited by 1,631
A neural basis for lexical retrieval
Damásio, H., Grabowski, T. J., Tranel, D., Hichwa, R. D., & Damásio, A. R. (1996) · Nature · doi:10.1038/380499a0 · Cited by 1,587
The Selective Impairment of Semantic Memory
Warrington, E. (1975) · Quarterly Journal of Experimental Psychology · doi:10.1080/14640747508400525 · Cited by 1,509
Semantic memory and the brain: structure and processes
Martin, A., & Chao, L. L. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00196-3 · Cited by 1,339
Semantic Cognition
Rogers, T. T., & McClelland, J. L. (2004) · The MIT Press eBooks · doi:10.7551/mitpress/6161.001.0001 · Cited by 1,161

Show all 43 references

Research works printed but not linked: 2

10.1016/S0028-3932(00)00034-8 · DOI · Paper page
10.1037/0278-7393.6.2.174 · DOI

Sorted by citations

Items 201–300 of 397

Using neurostimulation to understand the impact of pre-morbid individual differences on post-lesion outcomes
Woollams, A. M., Madrid, G., & Ralph, M. A. L. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1707162114 · Cited by 22
Self-citation
Task difficulty modulates brain-behavior correlations in language production and cognitive control: Behavioral and fMRI evidence from a phonological go/no-go picture-naming paradigm
Zhang, H., Eppes, A., Beatty‐Martínez, A. L., Navarro‐Torres, C. A., & Diaz, M. T. (2018) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-018-0616-2 · Cited by 27
Group membership dictates the neural correlates of social optimism biases
Dricu, M., Schüpbach, L., Bristle, M., Wiest, R., Moser, D. A., & Aue, T. (2020) · Scientific Reports · doi:10.1038/s41598-020-58121-4 · Cited by 22
Processing of Degraded Speech in Brain Disorders
Jiang, J., Benhamou, E., Waters, S., Johnson, J. C. S., Volkmer, A., Weil, R. S., Marshall, C. R., Warren, J. D., & Hardy, C. J. D. (2021) · Brain Sciences · doi:10.3390/brainsci11030394 · Cited by 18
Disentangling Semantic Composition and Semantic Association in the Left Temporal Lobe
Li, J., & Liina Pylkkänen, A. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2317-20.2021 · Cited by 28
Dissociating the semantic function of two neighbouring subregions in the left lateral anterior temporal lobe
Sanjuán, A., Hope, T. M. H., Jones, Ō. P., Prejawa, S., Oberhuber, M., Guerin, J. B., Seghier, M. L., Green, D. W., & Price, C. J. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.12.004 · Cited by 21
A Conceptual Lemon: Theta Burst Stimulation to the Left Anterior Temporal Lobe Untangles Object Representation and Its Canonical Color
Chiou, R. Y.-C., Sowman, P. F., Etchell, A. C., & Rich, A. N. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00536 · Cited by 21
Selective verbal recognition memory impairments are associated with atrophy of the language network in non-semantic variants of primary progressive aphasia
Nilakantan, A. S., Voss, J. L., Weıntraub, S., Mesulam, M. M., & Rogalski, E. J. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.04.006 · Cited by 21
Feature Uncertainty Predicts Behavioral and Neural Responses to Combined Concepts
Solomon, S. H., & Thompson‐Schill, S. L. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.2926-19.2020 · Cited by 20
The Differential Contributions of Conceptual Representation Format and Language Structure to Levels of Semantic Abstraction Capacity
Gainotti, G. (2017) · Neuropsychology Review · doi:10.1007/s11065-016-9339-8 · Cited by 20
The Emotional Facet of Subjective and Neural Indices of Similarity
Riberto, M., Pobric, G., & Talmi, D. (2019) · Brain Topography · doi:10.1007/s10548-019-00743-7 · Cited by 18
Self-citation
The time course of cross-modal representations of conceptual categories
Dirani, J., & Liina Pylkkänen, A. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120254 · Cited by 19
Brain function, structure and genomic data are linked but show different sensitivity to duration of illness and disease stage in schizophrenia
Luo, N., Tian, L., Calhoun, V. D., Chen, J., Lin, D., Vergara, V. M., Rao, S., Yang, J., Zhuo, C., Xu, Y. J., et al. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101887 · Cited by 20
Role of the anterior temporal lobes in semantic representations: Paradoxical results of a cTBS study
Bonnı̀, S., Koch, G., Miniussi, C., Bassi, M. S., Caltagirone, C., & Gainotti, G. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.11.002 · Cited by 19
rTMS evidence for a dissociation in short-term memory for spoken words and nonwords
Savill, N. J., Cornelissen, P. L., Pahor, A., & Jefferies, E. (2018) · Cortex · doi:10.1016/j.cortex.2018.07.021 · Cited by 18
Self-citation
Neural network bases of thematic semantic processing in language production
Blackett, D. S., Varkey, J., Wilmskoetter, J., Roth, R., Andrews, K., Busby, N., Gleichgerrcht, E. L., Desai, R. H., Riccardi, N., Basilakos, A., et al. (2022) · Cortex · doi:10.1016/j.cortex.2022.08.007 · Cited by 20
Is motor knowledge part and parcel of the concepts of manipulable artifacts? Clues from a case of upper limb aplasia
Vannuscorps, G., Andres, M., & Pillon, A. (2013) · Brain and Cognition · doi:10.1016/j.bandc.2013.11.009 · Cited by 19
The Neurobiology of Lexical Access
Davis, M. H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-407794-2.00044-4 · Cited by 19
Verbal Fluency in Mild Alzheimer’s Disease: Transcranial Direct Current Stimulation over the Dorsolateral Prefrontal Cortex
Smirni, D., Oliveri, M., Misuraca, E., Catania, A., Vernuccio, L., Picciolo, V., Inzerillo, F., Barbagallo, M., Cipolotti, L., & Turriziani, P. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210003 · Cited by 19
Time-Lagged Multidimensional Pattern Connectivity (TL-MDPC): An EEG/MEG pattern transformation based functional connectivity metric
Rahimi, S., Jackson, R. L., Farahibozorg, S.-R., & Hauk, O. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.119958 · Cited by 20
Frontotemporal stimulation modulates semantically-guided visual search during confrontation naming: A combined tDCS and eye tracking investigation
Binney, R. J., Ashaie, S. A., Zuckerman, B. M., Hung, J., & Reilly, J. J. (2018) · Brain and Language · doi:10.1016/j.bandl.2018.04.004 · Cited by 17
Semantic control and modality: An input processing deficit in aphasia leading to deregulated semantic cognition in a single modality
Thompson, H. E., & Jefferies, E. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.06.030 · Cited by 21
Self-citation
Beta modulation reflects name retrieval in the human anterior temporal lobe: an intracranial recording study
Abel, T. J., Rhone, A. E., Nourski, K. V., Ando, T. K., Oya, H., Kovach, C. K., Kawasaki, H., Howard, M. A., & Tranel, D. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00012.2016 · Cited by 17
Neural substrates of amodal and modality-specific semantic processing within the temporal lobe: A lesion-behavior mapping study of semantic dementia
Chen, Y., Chen, K., Ding, J., Zhang, Y., Yang, Q., Lv, Y., Guo, Q., & Zaizhu Han, A. (2019) · Cortex · doi:10.1016/j.cortex.2019.05.014 · Cited by 16
Language
Cattaneo, L. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-53497-2.00054-1 · Cited by 16
fMRI of Language Systems: Methods and Applications
Binder, J. R. (2011) · Springer eBooks · doi:10.1007/978-1-4419-0345-7_23 · Cited by 17
Characterizing and decomposing the neural correlates of individual differences in reading ability among adolescents with task-based fMRI
Wang, K., Leopold, D. R., Banich, M. T., Reineberg, A. E., Willcutt, E. G., Cutting, L. E., Tufo, S. N. D., Thompson, L. A., Opfer, J. E., Kanayet, F. J., et al. (2019) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2019.100647 · Cited by 16
Neurochemical profiles of the anterior temporal lobe predict response of repetitive transcranial magnetic stimulation on semantic processing
Jung, J., Williams, S. R., Nezhad, F. S., & Ralph, M. A. L. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119386 · Cited by 18
Self-citation
Spatiotemporal Properties of Common Semantic Categories for Words and Pictures
Bezsudnova, Y., Quinn, A. J., Wynn, S. C., & Jensen, O. B. (2024) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_02182 · Cited by 18
Audiovisual integration supports face–name associative memory formation
Lee, H. L., Stirnberg, R., Stöcker, T., & Axmacher, N. (2017) · Cognitive Neuroscience · doi:10.1080/17588928.2017.1327426 · Cited by 15
Cathodal tDCS of the bilateral anterior temporal lobes facilitates semantically-driven verbal fluency
Binney, R. J., Zuckerman, B. M., Waller, H. N., Hung, J., Ashaie, S. A., & Reilly, J. J. (2018) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2018.01.009 · Cited by 15
The Ventral Anterior Temporal Lobe has a Necessary Role in Exception Word Reading
Ueno, T., Meteyard, L., Hoffman, P., & Murayama, K. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy131 · Cited by 15
Representational similarity learning reveals a graded multidimensional semantic space in the human anterior temporal cortex
Cox, C. R., Rogers, T. T., Shimotake, A., Kikuchi, T., Kunieda, T., Miyamoto, S., Takahashi, R., Matsumoto, R., Ikeda, A., & Ralph, M. A. L. (2024) · Imaging Neuroscience · doi:10.1162/imag_a_00093 · Cited by 14
Self-citation
Does the sound of a barking dog activate its corresponding visual form? An fMRI investigation of modality-specific semantic access
Reilly, J. J., Garcia, A. M., & Binney, R. J. (2016) · Brain and Language · doi:10.1016/j.bandl.2016.05.006 · Cited by 14
Attentional Reinforcement Learning in the Brain
Yamakawa, H. (2020) · New Generation Computing · doi:10.1007/s00354-019-00081-z · Cited by 18
Convergence of distinct functional networks supporting naming and semantic recognition in the left inferior frontal gyrus
Xu, Z., Shen, B., Taji, W., Sun, P., & Naya, Y. (2020) · Human Brain Mapping · doi:10.1002/hbm.24953 · Cited by 15
An amodal shared resource model of language-mediated visual attention
Smith, A. C., Padraic Monaghan, B., & Huettig, F. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00528 · Cited by 14
The Role of the Left Anterior Temporal Lobe for Unpredictable and Complex Mappings in Word Reading
Joyal, M., Brambati, S. M., Laforce, R. J., Montembeault, M., Boukadi, M., Rouleau, I., Macoir, J., Joubert, S., Fecteau, S., & Wilson, M. A. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00517 · Cited by 13
Multimodal comprehension in left hemisphere stroke patients
Vigliocco, G., Krason, A., Stoll, H., Monti, A., & Buxbaum, L. J. (2020) · Cortex · doi:10.1016/j.cortex.2020.09.025 · Cited by 13
Word-producing brain: Contribution of the left anterior middle temporal gyrus to word production patterns in spoken language
Sugimoto, H., Abe, M., & Otake, M. (2023) · Brain and Language · doi:10.1016/j.bandl.2023.105233 · Cited by 12
Neural Representations of Concept Knowledge
Bauer, A. J., & Just, M. A. (2019) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190672027.013.21 · Cited by 13
Neuroplasticity in F16 fighter jet pilots
Radstake, W. E., Jillings, S., Laureys, S., Athena Demertzi, A., Sunaert, S. G., Ombergen, A. V., & Wuyts, F. L. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1082166 · Cited by 11
Role of the posterior temporal lobe during language tasks
Choi, Y., Park, H. K., & Paik, N. (2015) · Neuroreport · doi:10.1097/wnr.0000000000000339 · Cited by 11
Characterizing contrast origins and noise contribution in spin-echo EPI BOLD at 3 T
Ragot, D. M., & Chen, J. J. (2018) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2018.11.005 · Cited by 11
Neurophysiological evidence for crossmodal (face-name) person-identity representation in the human left ventral temporal cortex
Volfart, A., Jonas, J., Maillard, L. G., Colnat‐Coulbois, S., & Rossion, B. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000659 · Cited by 10
Transcranial direct current stimulation over the left anterior temporal lobe during memory retrieval differentially affects true and false recognition in the DRM task
Friehs, M. A., Greene, C. M., & Pastötter, B. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15337 · Cited by 10
Familiarity for famous faces and names is not equally subtended by the right and left temporal poles. Evidence from an rTMS study
Ranieri, F., Ferraccioli, M., Bassi, M. S., Musumeci, G., Lazzaro, V. D., Gainotti, G., & Marra, C. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.07.010 · Cited by 10
Addressing long-standing controversies in conceptual knowledge representation in the temporal pole: A cross-modal paradigm
Likova, L. T. (2017) · Electronic Imaging · doi:10.2352/issn.2470-1173.2017.14.hvei-155 · Cited by 10
The nature of impairments of memory in patients with end-stage renal disease (ESRD)
Jones, D. J. W., Harris, J. P., Vaux, E. C., Hadid, R., Kean, R., & Butler, L. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.05.008 · Cited by 10
The Perspective from Cognitive Neuroscience
Kemmerer, D. L. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780190682620.003.0002 · Cited by 9
Cognitive and Anatomical Underpinnings of the Conceptual Knowledge for Common Objects and Familiar People: A Repetitive Transcranial Magnetic Stimulation Study
Campanella, F., Fabbro, F., & Urgesi, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064596 · Cited by 9
A specific cognitive deficit within semantic cognition across a multi-generational family
Briscoe, J., Chilvers, R., Baldeweg, T., & Skuse, D. (2012) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2012.0894 · Cited by 9
Semantic Integration Demands Modulate Large‐Scale Network Interactions in the Brain
Nieberlein, L., Martin, S., Williams, K. A., Gussew, A., Cyriaks, S. D., Scheer, M., Rampp, S., Prell, J., & Hartwigsen, G. (2024) · Human Brain Mapping · doi:10.1002/hbm.70113 · Cited by 9
Aging-related differences in the cortical network subserving intelligible speech
Fei, N., Ge, J., Wang, Y., & Gao, J. (2019) · Brain and Language · doi:10.1016/j.bandl.2019.104713 · Cited by 8
The White Matter Module-Hub Network of Semantics Revealed by Semantic Dementia
Sundqvist, M., Routier, A., Dubois, B., Olivier Colliot, A., & Teichmann, M. (2020) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01549 · Cited by 9
The good, the bad, and the ambivalent: Extrapolating affective values for 38,000+ Chinese words via a computational model
Wang, T., & Xu, X. (2023) · Behavior Research Methods · doi:10.3758/s13428-023-02274-3 · Cited by 8
Early adolescents show sustained susceptibility to cognitive interference by emotional distractors
Heim, S., Ihssen, N., Hasselhorn, M., & Keil, A. (2012) · Cognition & Emotion · doi:10.1080/02699931.2012.736366 · Cited by 8
Knowing what and where: TMS evidence for the dual neural basis of geographical knowledge
Hoffman, P., & Crutch, S. J. (2015) · Cortex · doi:10.1016/j.cortex.2015.11.021 · Cited by 8
Differential Involvement of the Anterior Temporal Lobes in Famous People Semantics
Chedid, G., Wilson, M. A., Provost, J.-S., Joubert, S., Rouleau, I., & Brambati, S. M. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.01333 · Cited by 8
The neural network associated with lexical-semantic knowledge about social groups
Piretti, L., Carnaghi, A., Campanella, F., Ambron, E., Škrap, M., & Rumiati, R. I. (2015) · Cortex · doi:10.1016/j.cortex.2015.06.024 · Cited by 8
Evidence for degraded low frequency verbal concepts in left resected temporal lobe epilepsy patients
Visser, M., Forn, C., Ralph, M. A. L., Hoffman, P., Ibáñez, A. G., Sunajuán, A., Negre, P. R., Villanueva, V., & Ávila, C. (2018) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2018.04.020 · Cited by 8
Self-citation
Overlapping connectivity gradients in the anterior temporal lobe underlie semantic cognitionPreprint
Faber, M., Przeździk, I., Fernández, G., Haak, K. V., & Beckmann, C. F. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.28.121137 · Cited by 9
Divergent and convergent creativity relate to different aspects of semantic control
Krieger‐Redwood, K., Lanzoni, L., Alam, T. R. G., Jackson, R. L., Smallwood, J., & Jefferies, E. (2025) · Imaging Neuroscience · doi:10.1162/imag_a_00502 · Cited by 7
Self-citation
Neural circuits underlying language control and modality control in bilinguals: An fMRI study
Liu, H., Guo, Z., Jiang, Y., Schwieter, J. W., & Wang, F. (2022) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2022.108430 · Cited by 7
The Role of the Temporal Lobe in Human Social Cognition
Bryant, K., Flattery, C. N. R., & Schurz, M. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108671187.009 · Cited by 7
Corroborating behavioral evidence for the interplay of representational richness and semantic control in semantic word processing
Bechtold, L., Bellebaum, C., Hoffman, P., & Ghio, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-85711-7 · Cited by 7
Direct neural evidence for the contrastive roles of the complementary learning systems in adult acquisition of native vocabulary
Gore, K. R., Woollams, A. M., Bruehl, S., Halai, A. D., & Ralph, M. A. L. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab422 · Cited by 7
Self-citation
Low-frequency repetitive transcranial magnetic stimulation of the anterior temporal lobes does not dissociate social versus nonsocial semantic knowledge
Wong, C. L., & Gallate, J. E. (2010) · Quarterly Journal of Experimental Psychology · doi:10.1080/17470218.2010.526232 · Cited by 7
Intrinsic Functional Connectivity in the Default Mode Network Predicts Mnemonic Discrimination: A Connectome-based Modeling ApproachPreprint
Wahlheim, C. N., Christensen, A. P., Reagh, Z. M., & Cassidy, B. S. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.09.451777 · Cited by 7
Decoding semantic representations in mind and brainPreprint
Frisby, S. L., Halai, A. D., Cox, C. R., Ralph, M. A. L., & Rogers, T. T. (2022) · doi:10.31234/osf.io/6kjtf · Cited by 7
Self-citation
Mapping Contributions of the Anterior Temporal Semantic Hub to the Processing of Abstract and Concrete Verbs
Muraki, E. J., Pexman, P. M., & Binney, R. J. (2025) · Human Brain Mapping · doi:10.1002/hbm.70210 · Cited by 7
Language comprehension dependent on emotional context: A magnetoencephalography study
Ihara, A. S., Wei, Q., Matani, A., Fujimaki, N., Yagura, H., Nogai, T., Umehara, H., & Murata, T. (2011) · Neuroscience Research · doi:10.1016/j.neures.2011.09.011 · Cited by 6
The role of GABA in semantic memory and its neuroplasticity
Williams, S., Ralph, M. A. L., & Jung, J. (2025) · eLife · doi:10.7554/elife.91771.4 · Cited by 8
Self-citation
Morphometric correlates of anomia in patients with small left temporopolar lesions
Alemán‐Gómez, Y., Poch, C., Toledano, R., Jiménez‐Huete, A., García‐Morales, I., Gil‐Nagel, A., & Campo, P. (2019) · Journal of Neuropsychology · doi:10.1111/jnp.12184 · Cited by 6
Semantic Interference through Multiple Distractors in Picture Naming in People with Aphasia
van Scherpenberg, C., Rahman, R. A., Regenbrecht, F., & Obrig, H. (2021) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01731 · Cited by 6
Bayesian stroke modeling details sex biases in the white matter substrates of aphasia
Kernbach, J. M., Hartwigsen, G., Lim, J., Bae, H., Yu, K., Schlaug, G., Bonkhoff, A. K., Rost, N. S., & Bzdok, D. (2023) · Communications Biology · doi:10.1038/s42003-023-04733-1 · Cited by 7
A Neuropastoral Care and Counseling Assessment of Glossolalia: A Theosocial Cognitive Study
Johnson, K. D. (2009) · Journal of Health Care Chaplaincy · doi:10.1080/08854726.2010.492698 · Cited by 6
The role of GABA in semantic memory and its neuroplasticityPreprint
Jung, J., Williams, S. R., & Ralph, M. A. L. (2023) · eLife · doi:10.7554/elife.91771 · Cited by 7
Self-citation
Perceiving and misperceiving speech: lexical and sublexical processing in the superior temporal lobes
Tolkacheva, V., Brownsett, S. L. E., McMahon, K. L., & de Zubicaray, G. I. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae087 · Cited by 6
Innate network mechanisms of temporal pole for semantic cognition in neonatal and adult twin studies
Zhu, Z., Yang, H., Wen, H., Hung, J., Hu, Y., Yanchao Bi, A., & Yu, X. (2025) · Nature Communications · doi:10.1038/s41467-025-58896-y · Cited by 5
Multimodal feature binding in object memory retrieval using event-related potentials: Implications for models of semantic memory
Chiang, H., Spence, J. S., Eroh, J., Maguire, M. J., Kraut, M. A., & Hart, J. (2020) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2020.04.024 · Cited by 5
A MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasia
Pineault, J., Jolicœur, P., Grimault, S., Lacombe, J., Brambati, S. M., Bier, N., Chayer, C., & Joubert, S. (2019) · Neurocase · doi:10.1080/13554794.2019.1631853 · Cited by 5
Cathodal tDCS stimulation of left anterior temporal lobe eliminates cross-category color discrimination response time advantage
Akbıyık, S., Göksun, T., & Balcı, F. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112682 · Cited by 5
Improving the sensitivity of spin‐echo fMRI at 3T by highly accelerated acquisitions
Barghoorn, A., Riemenschneider, B., Hennig, J., & LeVan, P. (2021) · Magnetic Resonance in Medicine · doi:10.1002/mrm.28715 · Cited by 5
For richer or poorer? Imageability effects in semantic dementia patients’ reading aloud
Woollams, A. M. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.03.023 · Cited by 5
Semantic Cognition: Its Nature, Its Development, and Its Neural Basis
McClelland, J. L., Rogers, T. T., Patterson, K. E., Dilkina, K., & Ralph, M. A. L. (2009) · The Cognitive Neurosciences · doi:10.7551/mitpress/8029.003.0092 · Cited by 5
Self-citation
An investigation of phonological and semantic control using TMS and fMRI
Krieger‐Redwood, K. (2012) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York) · Cited by 5
Drawing Conclusions: An Exploration of the Cognitive and Neuroscientific Foundations of Representational Drawing
Chamberlain, R. (2013) · UCL Discovery (University College London) · Cited by 5
NEURAL INTEGRATION OF MULTIMODAL EVENTS
Vettel, J. M. (2009) · ProQuest Demo Repository · doi:10.7301/z0vq30zr · Cited by 6
The neural organisation of language production: Evidence from neuroimaging and neuromodulationPreprint
de Zubicaray, G. I. (2022) · doi:10.31234/osf.io/pf5sk · Cited by 5
Transcranial focused ultrasound stimulation of the anterior temporal lobe enhances semantic memory by modulating brain morphology, neurochemistry and neural dynamicsPreprint
Jung, J., Atkinson-Clément, C., Kaiser, M., & Ralph, M. A. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.10.642483 · Cited by 5
Self-citation
Disruption of Anterior Temporal Lobe Reduces Distortions in Memory From Category Knowledge
Tompary, A., Xia, A., Coslett, H. B., & Thompson‐Schill, S. L. (2023) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_02053 · Cited by 5
White matter network underlying semantic processing: evidence from stroke patients
Xiao, X., Dong, Z., Yu, M., Ding, J., Zhang, M., Cruz, S., Zaizhu Han, A., & Chen, Y. (2024) · Brain Communications · doi:10.1093/braincomms/fcae058 · Cited by 4
Contributions of left and right anterior temporal lobes to semantic cognition: Evidence from patients with small temporopolar lesions
Poch, C., Toledano, R., García‐Morales, I., Alemán‐Gómez, Y., Gil‐Nagel, A., & Campo, P. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107738 · Cited by 4
Patterns of Impaired Neurocognitive Performance on the Global Neuropsychological Assessment, and Their Brain Structural Correlates in Recent-onset and Chronic Schizophrenia
Mohan, V., Parekh, P., Lukose, A., Moirangthem, S., Saini, J. S., Schretlen, D. J., & John, J. P. (2023) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2023.21.2.340 · Cited by 4
Different patterns of spoken and written word comprehension deficit in aphasic stroke patients
Crutch, S. J., & Warrington, E. K. (2011) · Cognitive Neuropsychology · doi:10.1080/02643294.2012.673481 · Cited by 4
All spectral frequencies of neural activity reveal semantic representation in the human anterior ventral temporal cortex
Frisby, S. L., Halai, A. D., Cox, C. R., Clarke, A., Shimotake, A., Kikuchi, T., Kuneida, T., Arakawa, Y., Takahashi, R., Ikeda, A., et al. (2026) · Imaging Neuroscience · doi:10.1162/imag.a.1201 · Cited by 3
Self-citation
Verbal semantic expertise is associated with reduced functional connectivity between left and right anterior temporal lobes
Wu, W., & Hoffman, P. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae256 · Cited by 4
fMRI of Language Systems: Methods and Applications
Binder, J. R. (2023) · Springer eBooks · doi:10.1007/978-3-031-10909-6_26 · Cited by 3
Topological Alterations and Symptom-Relevant Modules in the Whole-Brain Structural Network in Semantic Dementia
Ding, J., Chen, K., Zhang, W., Li, M., Chen, Y., Yang, Q., Lv, Y., Guo, Q., & Zaizhu Han, A. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-170449 · Cited by 3

Authors: Pobric, G., Jefferies, E., & Ralph, M. A. L.
Affiliations: University of Manchester (GB)
ORCID: Pobric, Gorana
Jefferies, Elizabeth
Ralph, Matthew A. Lambon
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 2007-12-11
Volume: 104
Issue: 50
Pages: 20137-20141
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.0707383104
PMC: PMC2148435
OpenAlex: W2169670326
Cited by: 398
References: 43
Citations by year: 2026: 15 · 2025: 18 · 2024: 11 · 2023: 15 · 2022: 22 · 2021: 22 · 2020: 27 · 2019: 31 · 2018: 22 · 2017: 26 · 2016: 28 · 2015: 28 · 2014: 21 · 2013: 21 · 2012: 25
FWCI: 7.35
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Research Explorer (The University of Manchester) (submittedVersion, other-oa)
Funders: Wellcome Trust (078734/Z05/Z)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: anterior temporal lobe, semantic representation, semantic dementia, repetitive transcranial magnetic stimulation, semantic impairment, picture naming, word comprehension, semantic processing
MeSH terms: Adult, Dementia, Female, Health, Humans, Male, Semantics, Temporal Lobe, Transcranial Magnetic Stimulation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Anterior temporal lobes mediate semantic representation: Mimicking semantic dementia by using rTMS in normal participants

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks