Bringing the genetics of macular degeneration into focus
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Genetic studies suggest modification of the susceptibility effect of ARMS2 by smoking, consistent with its involvement in mitochondrial function.
“Genetic studies also suggest modification of the susceptibility effect of ARMS2 by smoking (128), consistent with its involvement in mitochondrial function (66, 82).”
From Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration (2009) · cites this paper as [66]
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Cites
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- Authors
- Haines, J. L., Spencer, K. M., & Pericak-Vance, M. A.
- Affiliations
- Vanderbilt University Medical Center (US)
- Miami Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL 33101
- ORCID
- Haines, Jonathan L.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2007-10-23
- Volume
- 104
- Issue
- 43
- Pages
- 16725-16726
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2040461
- OpenAlex
- W2082139719
- Cited by
- 15
- References
- 26
- Citations by year
- 2019: 1 · 2014: 2 · 2012: 2
- FWCI
- 2.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- macular degeneration, genetics, genetic susceptibility, age-related macular degeneration
- MeSH terms
- Chromosomes, Human, Humans, Genetic Linkage, Macular Degeneration, Mutation, Polymorphism, Single Nucleotide
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