The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Serotonin is necessary for place memory in Drosophila
Open accessAbstract
Biogenic amines, such as serotonin and dopamine, can be important in reinforcing associative learning. This function is evident as changes in memory performance with manipulation of either of these signals. In the insects, evidence begins to argue for a common role of dopamine in negatively reinforced memory. In contrast, the role of the serotonergic system in reinforcing insect associative learning is either unclear or controversial. We investigated the role of both of these signals in operant place learning in Drosophila . By genetically altering serotonin and dopamine levels, manipulating the neurons that make serotonin and dopamine, and pharmacological treatments we provide clear evidence that serotonin, but not dopamine, is necessary for place memory. Thus, serotonin can be critical for memory formation in an insect, and dopamine is not a universal negatively reinforcing signal.
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A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila
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Specific Dopaminergic Neurons for the Formation of Labile Aversive Memory
Aso, Y., Siwanowicz, I., Bräcker, L., Ito, K., Kitamoto, T., & Tanimoto, H. (2010) · Current Biology · doi:10.1016/j.cub.2010.06.048 · Cited by 324
Self-citationDopaminergic modulation of sucrose acceptance behavior in Drosophila
Marella, S., Mann, K., & Scott, K. (2012) · Neuron · doi:10.1016/j.neuron.2011.12.032 · Cited by 240
Behavioral consequences of dopamine deficiency in the Drosophila central nervous system
Riemensperger, T., Isabel, G., Coulom, H., Neuser, K., Seugnet, L., Kume, K., Iché-Torres, M., Cassar, M., Strauss, R., Preat, T., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010930108 · Cited by 265
Metadata
- Authors
- Sitaraman, D., Zars, M., LaFerriere, H., Chen, Y.-C., Sable-Smith, A., Kitamoto, T., Rottinghaus, G. E., & Zars, T.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2008-04-08
- Volume
- 105
- Issue
- 14
- Pages
- 5579-5584
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2089427933
- Cited by
- 289
- References
- 60
- FWCI
- 6.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sitaraman, D., Zars, M., LaFerriere, H., Chen, Y.-C., Sable-Smith, A., Kitamoto, T., Rottinghaus, G. E., & Zars, T. (2008). Serotonin is necessary for place memory in Drosophila. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0710168105
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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