The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Hydrogen and oxygen isotope ratios in human hair are related to geography
Open accessAbstract
We develop and test a model to predict the geographic region-of-origin of humans based on the stable isotope composition of their scalp hair. This model incorporates exchangeable and nonexchangeable hydrogen and oxygen atoms in amino acids to predict the δ 2 H and δ 18 O values of scalp hair (primarily keratin). We evaluated model predictions with stable isotope analyses of human hair from 65 cities across the United States. The model, which predicts hair isotopic composition as a function of drinking water, bulk diet, and dietary protein isotope ratios, explains >85% of the observed variation and reproduces the observed slopes relating the isotopic composition of hair samples to that of local drinking water. Based on the geographical distributions of the isotope ratios of tap waters and the assumption of a “continental supermarket” dietary input, we constructed maps of the expected average H and O isotope ratios in human hair across the contiguous 48 states. Applications of this model and these observations are extensive and include detection of dietary information, reconstruction of historic movements of individuals, and provision of region-of-origin information for unidentified human remains.
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Cites
USING STABLE ISOTOPES TO ESTIMATE TROPHIC POSITION: MODELS, METHODS, AND ASSUMPTIONS
Post, D. M. (2002) · Ecology · doi:10.1890/0012-9658(2002)083[0703:usitet]2.0.co;2 · Cited by 6,759
Primary structure effects on peptide group hydrogen exchange
Bai, Y., Milne, J. S., Mayne, L., & Englander, S. W. (1993) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.340170110 · Cited by 1,902
Interpolating the isotopic composition of modern meteoric precipitation
Bowen, G. J., & Revenaugh, J. (2003) · Water Resources Research · doi:10.1029/2003wr002086 · Cited by 1,288
Self-citationHobson, K. A., & Wassenaar, L. I. (1997) · Oecologia · doi:10.1007/s004420050068 · Cited by 579
Carbon isotope fractionation between diet, breath CO2, and bioapatite in different mammals
Passey, B. H., Robinson, T. F., Ayliffe, L. K., Cerling, T. E., Sponheimer, M., Dearing, M. D., Roeder, B. L., & Ehleringer, J. R. (2005) · Journal of Archaeological Science · doi:10.1016/j.jas.2005.03.015 · Cited by 576
Self-citationInvestigations into the effect of diet on modern human hair isotopic values
O'Connell, T. C., & Hedges, R. E. M. (1999) · American Journal of Physical Anthropology · doi:10.1002/(sici)1096-8644(199904)108:4<409::aid-ajpa3>3.0.co;2-e · Cited by 422
Measurement of Gastric Functions During Digestion of Ordinary Solid Meals in Man
Malagelada, J.-R., Longstreth, G. F., Summerskill, W. H. J., & Go, V. L. W. (1976) · Gastroenterology · doi:10.1016/s0016-5085(76)80010-8 · Cited by 338
Mekota, A., Grupe, G., Ufer, S., & Cuntz, U. (2006) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2477 · Cited by 337
Wassenaar, L. I., & Hobson, K. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15436 · Cited by 330
18 O Labeling: a tool for proteomics
Stewart, I. I., Thomson, T., & Figeys, D. (2001) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.525 · Cited by 327
Cited by
Isoscapes: Spatial Pattern in Isotopic Biogeochemistry
Bowen, G. J. (2010) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev-earth-040809-152429 · Cited by 518
Self-citationFetal Bovine Serum (FBS): past ‐ present ‐ future
van der Valk, J. (2018) · ALTEX · doi:10.14573/altex.1705101 · Cited by 481
The isotopic anatomies of molecules and minerals
Eiler, J. M. (2013) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev-earth-042711-105348 · Cited by 96
Investigating human geographic origins using dual-isotope (87Sr/86Sr, δ18O) assignment approaches
Laffoon, J. E., Sonnemann, T. F., Shafie, T., Hofman, C. L., Brandes, U., & Davies, G. R. (2017) · PLOS ONE · doi:10.1371/journal.pone.0172562 · Cited by 88
Analysis of stable isotopes: from the Archaic to the Horticultural Communities in Central Chile
Sanhueza, L., & Falabella, F. (2010) · Current Anthropology · doi:10.1086/649055 · Cited by 30
Metadata
- Authors
- Ehleringer, J. R., Bowen, G. J., Chesson, L. A., West, A. G., Podlesak, D. W., & Cerling, T. E.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2008-02-26
- Volume
- 105
- Issue
- 8
- Pages
- 2788-2793
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2082919244
- Cited by
- 384
- References
- 29
- FWCI
- 21.19
- Type
- journal article
- Language
- en
- Open access
- green
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- Ehleringer, J. R., Bowen, G. J., Chesson, L. A., West, A. G., Podlesak, D. W., & Cerling, T. E. (2008). Hydrogen and oxygen isotope ratios in human hair are related to geography. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0712228105
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
