The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Plasticity in the organization and sequences of human KIR/ILT gene families
Open accessAbstract
The ≈1-Mb leukocyte receptor complex at 19q13.4 is a key polymorphic immunoregion containing all of the natural killer-receptor KIR and related ILT genes. When the organization of the leukocyte receptor complex was compared from two haplotypes, the gene content in the KIR region varied dramatically, with framework loci flanking regions of widely variable gene content. The ILT genes were more stable in number except for ILT 6, which was present only in one haplotype. Analysis of Alu repeats and comparison of KIR gene sequences, which are over 90% identical, are consistent with a recent origin.KIR genesis was followed by extensive duplication/deletion as well as intergenic sequence exchange, reminiscent of MHC class I genes, which provide KIR ligands.
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Cites
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Self-citationLAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes
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Cited by
Lanier, L. L. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115526 · Cited by 2,769
Natural killer cells and pregnancy
Moffett-King, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri886 · Cited by 1,235
MHC class I molecules and kirs in human history, health and survival
Parham, P. (2005) · Nature Reviews Immunology · doi:10.1038/nri1570 · Cited by 1,203
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Self-citationAllelic Polymorphism Synergizes with Variable Gene Content to Individualize Human KIR Genotype
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Metadata
- Authors
- Wilson, M. J., Torkar, M., Haude, A., Milne, S., Jones, T., Sheer, D., Beck, S., & Trowsdale, J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2000-04-18
- Volume
- 97
- Issue
- 9
- Pages
- 4778-4783
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2110036277
- Cited by
- 624
- References
- 34
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Wilson, M. J., Torkar, M., Haude, A., Milne, S., Jones, T., Sheer, D., Beck, S., & Trowsdale, J. (2000). Plasticity in the organization and sequences of human KIR/ILT gene families. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.080588597
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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