The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Single-particle kinetics of influenza virus membrane fusion
Open accessAbstract
Membrane fusion is an essential step during entry of enveloped viruses into cells. Conventional fusion assays are generally limited to observation of ensembles of multiple fusion events, confounding more detailed analysis of the sequence of the molecular steps involved. We have developed an in vitro , two-color fluorescence assay to monitor kinetics of single virus particles fusing with a target bilayer on an essentially fluid support. Analysis of lipid- and content-mixing trajectories on a particle-by-particle basis provides evidence for multiple, long-lived kinetic intermediates leading to hemifusion, followed by a single, rate-limiting step to pore formation. We interpret the series of intermediates preceding hemifusion as a result of the requirement that multiple copies of the trimeric hemagglutinin fusion protein be activated to initiate the fusion process.
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Cites
An introduction to probability theory and its applications
(1958) · Journal of the Franklin Institute · doi:10.1016/0016-0032(58)90688-4 · Cited by 29,269
An Introduction to Probability Theory and Its Applications.
Bharucha-Reid, A. T., & Feller, W. (1967) · The American Mathematical Monthly · doi:10.2307/2314609 · Cited by 6,066
An Introduction to Probability Theory.
Fristedt, B., & Moran, P. A. P. (1986) · Journal of the American Statistical Association · doi:10.2307/2288022 · Cited by 3,300
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
Skehel, J. J., & Wiley, D. C. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.531 · Cited by 2,706
Self-citationStructure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
Wilson, I. A., Skehel, J. J., & Wiley, D. C. (1981) · Nature · doi:10.1038/289366a0 · Cited by 2,525
Self-citationStructure of influenza haemagglutinin at the pH of membrane fusion
Bullough, P. A., Hughson, F. M., Skehel, J. J., & Wiley, D. C. (1994) · Nature · doi:10.1038/371037a0 · Cited by 1,564
Self-citationChan, D. C., & Kim, P. S. (1998) · Cell · doi:10.1016/s0092-8674(00)81430-0 · Cited by 1,277
Harrison, S. C. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1456 · Cited by 1,190
Self-citationProtein-Lipid Interplay in Fusion and Fission of Biological Membranes
Chernomordik, L. V., & Kozlov, M. M. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161504 · Cited by 782
Skehel, J. J., Bayley, P. M., Brown, E. B., Martin, S. R., Waterfield, M. D., White, J. M., Wilson, I. A., & Wiley, D. C. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.4.968 · Cited by 726
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Cited by
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
Diao, J., Grob, P., Cipriano, D. J., Kyoung, M., Zhang, Y., Shah, S., Nguyen, A., Padolina, M., Srivastava, A., Vrljic, M., et al. (2012) · eLife · doi:10.7554/elife.00109 · Cited by 170
Kyoung, M., Srivastava, A., Zhang, Y., Diao, J., Vrljic, M., Grob, P., Nogales, E., Chu, S., & Brunger, A. T. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107900108 · Cited by 154
A distinct tethering step is vital for vacuole membrane fusion
Zick, M., & Wickner, W. T. (2014) · eLife · doi:10.7554/elife.03251 · Cited by 61
High curvature promotes fusion of lipid membranes: Predictions from continuum elastic theory
Golani, G., & Schwarz, U. S. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.04.018 · Cited by 41
Metadata
- Authors
- Floyd, D. L., Ragains, J. R., Skehel, J. J., Harrison, S. C., & van Oijen, A. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2008-10-07
- Volume
- 105
- Issue
- 40
- Pages
- 15382-15387
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2127951618
- Cited by
- 264
- References
- 38
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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