The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore
Open accessAbstract
The sequencing of individual DNA strands with nanopores is under investigation as a rapid, low-cost platform in which bases are identified in order as the DNA strand is transported through a pore under an electrical potential. Although the preparation of solid-state nanopores is improving, biological nanopores, such as α-hemolysin (αHL), are advantageous because they can be precisely manipulated by genetic modification. Here, we show that the transmembrane β-barrel of an engineered αHL pore contains 3 recognition sites that can be used to identify all 4 DNA bases in an immobilized single-stranded DNA molecule, whether they are located in an otherwise homopolymeric DNA strand or in a heteropolymeric strand. The additional steps required to enable nanopore DNA sequencing are outlined.
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Cites
Mfold web server for nucleic acid folding and hybridization prediction
Zuker, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg595 · Cited by 13,404
What would you do if you could sequence everything?
Kahvejian, A., Quackenbush, J., & Thompson, J. F. (2008) · Nature Biotechnology · doi:10.1038/nbt1494 · Cited by 189
Cited by
Three decades of nanopore sequencing
Deamer, D., Akeson, M., & Branton, D. (2016) · Nature Biotechnology · doi:10.1038/nbt.3423 · Cited by 1,292
Li, W., Zhang, H., Assaraf, Y. G., Zhao, K., Xu, X., Xie, J., Yang, D.-H., & Chen, Z.-S. (2016) · Drug Resistance Updates · doi:10.1016/j.drup.2016.05.001 · Cited by 673
Tabatabaei, S. K., Pham, B., Pan, C., Liu, J., Chandak, S., Shorkey, S. A., Hernandez, A. G., Aksimentiev, A., Chen, M., Schroeder, C. M., et al. (2022) · Nano Letters · doi:10.1021/acs.nanolett.1c04203 · Cited by 63
Metadata
- Authors
- Stoddart, D., Heron, A. J., Mikhailova, E., Maglia, G., & Bayley, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2009-05-12
- Volume
- 106
- Issue
- 19
- Pages
- 7702-7707
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2154224094
- Cited by
- 482
- References
- 2
- FWCI
- 19.99
- Type
- journal article
- Language
- en
- Open access
- bronze
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