Amplification of signaling via cellular allosteric relay and protein disorder

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Is allostery an intrinsic property of all dynamic proteins?

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Evolutionarily conserved networks of residues mediate allosteric communication in proteins

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Allostery: Absence of a change in shape does not imply that allostery is not at play

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Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins

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Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

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Modeling the cAMP-induced Allosteric Transition Using the Crystal Structure of CAP-cAMP at 2.1 Å Resolution

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Cooperativity in Transcription Factor Binding to the Coactivator CREB-binding Protein (CBP)

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Signal Amplification by Allosteric Catalysis

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Membrane Localization of Scaffold Proteins Promotes Graded Signaling in the Yeast MAP Kinase Cascade

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A Computational Investigation of Allostery in the Catabolite Activator Protein

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Regulating highly dynamic unstructured proteins and their coding mRNAs

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A Scaffold Makes the Switch

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The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways

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Intrinsically disordered proteins play diverse roles in cell signaling

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Dynamic Allostery: Linkers Are Not Merely Flexible

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The Underappreciated Role of Allostery in the Cellular Network

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Dynamic protein–DNA recognition: beyond what can be seen

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Mechanisms of transcription factor selectivity

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Allo-network drugs: harnessing allostery in cellular networks

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Proteins MOVE! Protein dynamics and long-range allostery in cell signaling

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Evidence for a Strong Correlation Between Transcription Factor Protein Disorder and Organismic Complexity

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Towards the Idea of Molecular Brains

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Protein dynamics and conformational selection in bidirectional signal transduction

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Allo-Network Drugs: Extension of the Allosteric Drug Concept to Protein- Protein Interaction and Signaling Networks

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Structured Crowding and Its Effects on Enzyme Catalysis

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Proteins Recognizing DNA: Structural Uniqueness and Versatility of DNA-Binding Domains in Stem Cell Transcription Factors

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Precision medicine review: rare driver mutations and their biophysical classification

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The spatial structure of cell signaling systems

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Influence of Sequence Changes and Environment on Intrinsically Disordered Proteins

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Activation of Nanoscale Allosteric Protein Domain Motion Revealed by Neutron Spin Echo Spectroscopy

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How do transcription factors select specific binding sites in the genome?

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Structural Systems Pharmacology: The Role of 3D Structures in Next-Generation Drug Development

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A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery

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Protein function and allostery: a dynamic relationship

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Protein charge and mass contribute to the spatio‐temporal dynamics of protein–protein interactions in a minimal proteome

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Dynamic multiprotein assemblies shape the spatial structure of cell signaling

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Maximum Entropy Reconstructions of Dynamic Signaling Networks from Quantitative Proteomics Data

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How do dynamic cellular signals travel long distances?

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Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization

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“Fluctuograms” Reveal the Intermittent Intra-Protein Communication in Subtilisin Carlsberg and Correlate Mechanical Coupling with Co-Evolution

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Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)*

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Multiple‐Targeting and Conformational Selection in the Estrogen Receptor: Computation and Experiment

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Controlled mechanochemical coupling of anti-junctions in DNA origami arrays

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Bioinformatics Study of Cancer-Related Mutations within p53 Phosphorylation Site Motifs

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Classification of Genes and Putative Biomarker Identification Using Distribution Metrics on Expression Profiles

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An electrochemical method for detecting the biomarker 4-HPA by allosteric activation of Acinetobacter baumannii reductase C1 subunit

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Reconstitution of membrane symmetry breaking

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A FAMILY OF SPECTRAL OPERATIONS

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