The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene
Open accessAbstract
TOR (target of rapamycin) protein kinases were identified in yeasts, mammals, and Drosophila as central controllers of cell growth in response to nutrient and growth factors. Here we show that Arabidopsis thaliana possesses a single TOR gene encoding a protein able to complex with yeast 12-kDa FK506-binding protein and rapamycin despite the insensitivity of Arabidopsis vegetative growth to rapamycin. Analysis of two T-DNA insertion mutants shows that disruption of AtTOR leads to the premature arrest of endosperm and embryo development. A T-DNA-mediated translational fusion of AtTOR with the GUS reporter gene allows us to show that AtTOR is expressed in primary meristem, embryo, and endosperm, but not in differentiated cells. The implications of these features for the plant TOR pathway are discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
Chiu, M. I., Katz, H., & Berlin, V (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.26.12574 · Cited by 481
Cited by
Sugar signals and molecular networks controlling plant growth
Smeekens, S., Ma, J., Hanson, J., & Rolland, F. (2010) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2009.12.002 · Cited by 655
mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
Murakami, M., Ichisaka, T., Maeda, M., Oshiro, N., Hara, K., Edenhofer, F., Kiyama, H., Yonezawa, K., & Yamanaka, S. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.15.6710-6718.2004 · Cited by 624
Convergent energy and stress signaling
Baena-González, E., & Sheen, J. (2008) · Trends in Plant Science · doi:10.1016/j.tplants.2008.06.006 · Cited by 608
Autophagic Nutrient Recycling in Arabidopsis Directed by the ATG8 and ATG12 Conjugation Pathways
Thompson, A. R., Doelling, J. H., Suttangkakul, A., & Vierstra, R. D. (2005) · Plant Physiology · doi:10.1104/pp.105.060673 · Cited by 574
Suttangkakul, A., Li, F., Chung, T., & Vierstra, R. D. (2011) · The Plant Cell · doi:10.1105/tpc.111.090993 · Cited by 311
Metadata
- Authors
- Menand, B., Desnos, T., Nussaume, L., Berger, F., Bouchez, D., Meyer, C., & Robaglia, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2002-04-30
- Volume
- 99
- Issue
- 9
- Pages
- 6422-6427
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2001639563
- Cited by
- 493
- References
- 1
- FWCI
- 16.77
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. https://app.cochat.ai/papers/10.1073/pnas.092141899
- The paper
- Menand, B., Desnos, T., Nussaume, L., Berger, F., Bouchez, D., Meyer, C., & Robaglia, C. (2002). Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.092141899
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
