Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 308

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

High sensitivity nanoparticle detection using optical microcavities

Open access
Lu, Tao, Lee, Hansuek, Chen, Tong, Herchak, Steven, Kim, Ji-Hun, Fraser, Scott E., Flagan, Richard C., Vahala, Kerry·2011·Proceedings of the National Academy of Sciences

Abstract

We demonstrate a highly sensitive nanoparticle and virus detection method by using a thermal-stabilized reference interferometer in conjunction with an ultrahigh-Q microcavity. Sensitivity is sufficient to resolve shifts caused by binding of individual nanobeads in solution down to a record radius of 12.5 nm, a size approaching that of single protein molecules. A histogram of wavelength shift versus nanoparticle radius shows that particle size can be inferred from shift maxima. Additionally, the signal-to-noise ratio for detection of Influenza A virus is enhanced to 38∶1 from the previously reported 3∶1. The method does not use feedback stabilization of the probe laser. It is also observed that the conjunction of particle-induced backscatter and optical-path-induced shifts can be used to enhance detection signal-to-noise.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1073/pnas.1017962108

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 2 references

Cited by

See all 308

Metadata

Authors
Lu, T., Lee, H., Chen, T., Herchak, S., Kim, J.-H., Fraser, S. E., Flagan, R. C., & Vahala, K.
Venue
Proceedings of the National Academy of Sciences
Published
2011-03-28
Volume
108
Issue
15
Pages
5976-5979
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2042024782
Cited by
308
References
2
FWCI
23.40
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: High sensitivity nanoparticle detection using optical microcavities. https://app.cochat.ai/papers/10.1073/pnas.1017962108
The paper
Lu, T., Lee, H., Chen, T., Herchak, S., Kim, J.-H., Fraser, S. E., Flagan, R. C., & Vahala, K. (2011). High sensitivity nanoparticle detection using optical microcavities. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1017962108

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.