Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

Bowman, Tammy, Broome, Martin A., Sinibaldi, Dominic, Wharton, Walker, Pledger, W. J., Sedivy, John M., Irby, Rosalyn, Yeatman, Timothy +2 more·2001·Proceedings of the National Academy of Sciences

Cited by (487)

Items 201–300 of 487

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  2. Susceptibility of Signal Transducer and Activator of Transcription-1-Deficient Mice to Pulmonary Fibrogenesis
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  3. STAT3 in tissue fibrosis: Is there a role in the lung?
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  4. Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles
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  5. Inhibitory roles of signal transducer and activator of transcription 3 in antitumor immunity during carcinogen-induced lung tumorigenesis.
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  6. STAT3: A Central Mediator of Pulmonary Fibrosis?
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  7. Indirubin-3′-Monoxime Blocks Vascular Smooth Muscle Cell Proliferation by Inhibition of Signal Transducer and Activator of Transcription 3 Signaling and Reduces Neointima Formation In Vivo
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  8. c‐myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3
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  9. Improving the prognosis for patients with glioblastoma: the rationale for targeting Src
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  10. The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma
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  11. Long noncoding RNA H19 competitively binds miR‐93‐5p to regulate STAT3 expression in breast cancer
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  12. Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement
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  13. Abl tyrosine kinase regulates a Rac/JNK and a Rac/Nox pathway for DNA synthesis and Myc expression induced by growth factors
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  14. Lycopene treatment inhibits activation of Jak1/Stat3 and Wnt/β-catenin signaling and attenuates hyperproliferation in gastric epithelial cells
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  15. Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling
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  16. Suppression of v-Src Transformation by Andrographolide via Degradation of the v-Src Protein and Attenuation of the Erk Signaling Pathway
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  17. Targeting Tyrosine Kinases and Autophagy in Prostate Cancer
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  18. Gambogic Acid Inhibits STAT3 Phosphorylation Through Activation of Protein Tyrosine Phosphatase SHP-1: Potential Role in Proliferation and Apoptosis
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  19. Making Myc
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  20. Phospho‐Stat3 expression and correlation with VEGF, p53, and Bcl‐2 in gastric carcinoma using tissue microarray
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  21. PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility
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  22. Cross-regulation of JAK and Src kinases
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  24. Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion
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  25. SRC Signaling in Cancer and Tumor Microenvironment
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  26. Src acts as the target of matrine to inhibit the proliferation of cancer cells by regulating phosphorylation signaling pathways
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  27. c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution
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  28. Constitutive activation of Stat5a by retrovirus integration in early pre-B lymphomas of SL/Kh strain mice
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  29. The Adaptor Protein Tom1L1 Is a Negative Regulator of Src Mitogenic Signaling Induced by Growth Factors
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  30. Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line
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  33. Molecular Cloning and Characterization of the Human AKT1 Promoter Uncovers Its Up-regulation by the Src/Stat3 Pathway
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  35. Signal Transducer and Activator of Transcription Factor 1 Mediates Apoptosis Induced by Hepatitis C Virus and HIV Envelope Proteins in Hepatocytes
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  37. MRTF-A and STAT3 synergistically promote breast cancer cell migration
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  41. Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF
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  44. Activated Src abrogates the Myc requirement for the G 0 /G 1 transition but not for the G 1 /S transition
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  49. Phosphatase of Regenerating Liver 3 (PRL3) Provokes a Tyrosine Phosphoproteome to Drive Prometastatic Signal Transduction
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  52. Hypoxia-induced SOCS3 is limiting STAT3 phosphorylation and NF-κB activation in congenital heart disease
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  56. The reactive oxygen species–Src–Stat3 pathway provokes negative feedback inhibition of apoptosis induced by high‐fluence low‐power laser irradiation
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  57. Zap70 Functions to Maintain Stemness of Mouse Embryonic Stem Cells by Negatively Regulating Jak1/Stat3/c-Myc Signaling
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  58. Loss of SOCS3 expression is associated with an increased risk of recurrent disease in breast carcinoma
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