The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Physical activity when young provides lifelong benefits to cortical bone size and strength in men
Abstract
Significance: Bones adapt to mechanical forces in youth to increase their size and strength but are more at risk for breaking later in life. Do the skeletal benefits of physical activity in youth persist with aging? Here we show at an upper extremity site that half of the benefit in bone size and one-third of the benefit in bone strength obtained from physical activity during youth are maintained throughout life, even though the bone mass benefits are lost. When physical activity was continued during aging, some mass and more strength benefits were preserved. These data suggest that physical activity during youth should be encouraged for lifelong bone health, with the focus being optimization of bone size rather than increasing mass.
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“Bone benefits acquired through exercise at young age can still persist several decades after cessation of exercise training [117].”
From Nutrition for Older Athletes: Focus on Sex-Differences (2021) · cites this paper as [117]
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Cited by
Estrogens and androgens in skeletal physiology and pathophysiology
Almeida, M., Laurent, M. R., Dubois, V., Claessens, F., O'Brien, C. A., Bouillon, R., Vanderschueren, D., & Manolagas, S. C. (2017) · Physiological Reviews · doi:10.1152/physrev.00033.2015 · Cited by 860
Beck, B. R., Daly, R. M., Singh, M. A. F., & Taaffe, D. R. (2017) · Journal of Science and Medicine in Sport · doi:10.1016/j.jsams.2016.10.001 · Cited by 366
Effects of Resistance Exercise on Bone Health
Hong, A. R., & Kim, S. W. (2018) · Endocrinology and Metabolism · doi:10.3803/enm.2018.33.4.435 · Cited by 291
Factors influencing peak bone mass gain
Zhu, X., & Zheng, H. (2021) · Frontiers of Medicine · doi:10.1007/s11684-020-0748-y · Cited by 160
Ng, C.-A., Gandham, A., Mesinovic, J., Owen, P. J., Ebeling, P. R., & Scott, D. (2023) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4899 · Cited by 36
Metadata
- Authors
- Warden, S. J., Mantila Roosa, S. M., Kersh, M. E., Hurd, A. L., Fleisig, G. S., Pandy, M. G., & Fuchs, R. K.
- Affiliations
- Center for Translational Musculoskeletal Research and
- Department of Mechanical Engineering, University of Melbourne, Parkville, VIC 3010, Australia; and
- American Sports Medicine Institute, Birmingham, AL 35205
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-03-24
- Volume
- 111
- Issue
- 14
- Pages
- 5337-5342
- ISSN
- 0027-8424
- 1091-6490
- Cited by
- 235
- References
- 1
- Language
- en
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- CoChat. (2026). Citation check: Physical activity when young provides lifelong benefits to cortical bone size and strength in men. https://app.cochat.ai/papers/10.1073/pnas.1321605111
- The paper
- Warden, S. J., Mantila Roosa, S. M., Kersh, M. E., Hurd, A. L., Fleisig, G. S., Pandy, M. G., & Fuchs, R. K. (2014). Physical activity when young provides lifelong benefits to cortical bone size and strength in men. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1321605111
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
