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Cited by 189

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis

Open access
Kim, YongTae, Lobatto, Mark E., Kawahara, Tomohiro, Lee Chung, Bomy, Mieszawska, Aneta J., Sanchez-Gaytan, Brenda L., Fay, Francois, Senders, Max L., Calcagno, Claudia, Becraft, Jacob, Tun Saung, May, Gordon, Ronald E., Stroes, Erik S. G., Ma, Mingming, Farokhzad, Omid C., Fayad, Zahi A., Mulder, Willem J. M., Langer, Robert·2014·Proceedings of the National Academy of Sciences

Abstract

Significance: This study shows that an endothelialized microfluidic chip with controllable permeability can serve as a model for nanoparticle translocation across the permeable endothelium. Integration of this in vitro model and an in vivo rabbit model revealed that the extravasation of nanoparticles across the endothelium in atherosclerotic plaques depends on microvascular permeability. This approach represents a unique method for the assessment of nanoparticle behavior across the atherosclerotic endothelium, and may also serve as a valuable tool to study nanomedicine accumulation in a variety of other diseases.

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Metadata

Authors
Kim, Y., Lobatto, M. E., Kawahara, T., Lee Chung, B., Mieszawska, A. J., Sanchez-Gaytan, B. L., Fay, F., Senders, M. L., Calcagno, C., Becraft, J., Tun Saung, M., Gordon, R. E., Stroes, E. S. G., Ma, M., Farokhzad, O. C., Fayad, Z. A., Mulder, W. J. M., & Langer, R.
Venue
Proceedings of the National Academy of Sciences
Published
2014-01-06
Volume
111
Issue
3
Pages
1078-1083
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2091551811
Cited by
189
References
6
FWCI
7.81
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis. https://app.cochat.ai/papers/10.1073/pnas.1322725111
The paper
Kim, Y., Lobatto, M. E., Kawahara, T., Lee Chung, B., Mieszawska, A. J., Sanchez-Gaytan, B. L., Fay, F., Senders, M. L., Calcagno, C., Becraft, J., Tun Saung, M., Gordon, R. E., Stroes, E. S. G., Ma, M., Farokhzad, O. C., Fayad, Z. A., Mulder, W. J. M., & Langer, R. (2014). Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1322725111

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.