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Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi
Open accessAbstract
Significance: Wood decay fungi have historically been characterized as either white rot, which degrade all components of plant cell walls, including lignin, or brown rot, which leave lignin largely intact. Genomic analyses have shown that white-rot species possess multiple lignin-degrading peroxidases (PODs) and expanded suites of enzymes attacking crystalline cellulose. To test the adequacy of the white/brown-rot categories, we analyzed 33 fungal genomes. Some species lack PODs, and thus resemble brown-rot fungi, but possess the cellulose-degrading apparatus typical of white-rot fungi. Moreover, they appear to degrade lignin, based on decay analyses on wood wafers. Our results indicate that the prevailing paradigm of white rot vs. brown rot does not capture the diversity of fungal wood decay mechanisms.
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Fueling the future with fungal genomics
Grigoriev, I. V., Cullen, D., Goodwin, S. B., Hibbett, D., Jeffries, T. W., Kubicek, C. P., Kuske, C., Magnuson, J. K., Martin, F., Spatafora, J. W., et al. (2011) · Mycology · doi:10.1080/21501203.2011.584577 · Cited by 250
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Nagy, L. G., Riley, R., Bergmann, P. J., Krizsán, K., Martin, F. M., Grigoriev, I. V., Cullen, D., & Hibbett, D. S. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msw238 · Cited by 90
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Metadata
- Authors
- Riley, R., Salamov, A. A., Brown, D. W., Nagy, L. G., Floudas, D., Held, B. W., Levasseur, A., Lombard, V., Morin, E., Otillar, R., Lindquist, E. A., Sun, H., LaButti, K. M., Schmutz, J., Jabbour, D., Luo, H., Baker, S. E., Pisabarro, A. G., Walton, J. D., Blanchette, R. A., Henrissat, B., Martin, F., Cullen, D., Hibbett, D. S., & Grigoriev, I. V.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-06-23
- Volume
- 111
- Issue
- 27
- Pages
- 9923-9928
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2016399990
- Cited by
- 745
- References
- 6
- FWCI
- 70.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Riley, R., Salamov, A. A., Brown, D. W., Nagy, L. G., Floudas, D., Held, B. W., Levasseur, A., Lombard, V., Morin, E., Otillar, R., Lindquist, E. A., Sun, H., LaButti, K. M., Schmutz, J., Jabbour, D., Luo, H., Baker, S. E., Pisabarro, A. G., Walton, J. D., . . . Grigoriev, I. V. (2014). Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1400592111
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