The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis
Open accessAbstract
Significance: Saffron is a triploid, sterile species whose red stigmas constitute the most expensive spice on Earth. The color, the taste, and the aroma of the spice are owed to the crocus-specific apocarotenoid accumulation of crocetin/crocins, picrocrocin, and safranal. Through deep transcriptome analysis, we identified a novel carotenoid cleavage dioxygenase (CCD) whose expression profile parallels the production of crocetin. Using in bacterio , in vitro, and in planta functional assays, we demonstrate that CCD2 is the dioxygenase catalyzing the first dedicated step in saffron crocetin biosynthesis starting from the carotenoid zeaxanthin.
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Cited by
Carotenoid Metabolism in Plants
Nisar, N., Li, L., Lu, S., Khin, N. C., & Pogson, B. J. (2015) · Molecular Plant · doi:10.1016/j.molp.2014.12.007 · Cited by 1,255
Metadata
- Authors
- Frusciante, S., Diretto, G., Bruno, M., Ferrante, P., Pietrella, M., Prado-Cabrero, A., Rubio-Moraga, A., Beyer, P., Gomez-Gomez, L., Al-Babili, S., & Giuliano, G.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-08-05
- Volume
- 111
- Issue
- 33
- Pages
- 12246-12251
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2058301861
- Cited by
- 300
- References
- 39
- FWCI
- 8.62
- Type
- journal article
- Language
- en
- Open access
- green
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- Frusciante, S., Diretto, G., Bruno, M., Ferrante, P., Pietrella, M., Prado-Cabrero, A., Rubio-Moraga, A., Beyer, P., Gomez-Gomez, L., Al-Babili, S., & Giuliano, G. (2014). Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1404629111
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