The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Pervasive domestication of defective prophages by bacteria
Open accessAbstract
Significance: Several molecular systems with important adaptive roles have originated from the domestication of integrated phages (prophages). However, the evolutionary mechanisms and extent of prophage domestication remain poorly understood. In this work, we detected several hundred prophages originating from common integration events and described their dynamics of degradation within their hosts. Surprisingly, we observed strong conservation of the sequence of most vertically inherited prophages, including selection for genes encoding phage-specific functions. These results suggest pervasive domestication of parasites by the bacterial hosts. Because prophages account for a large fraction of bacterial genomes, phage domestication may drive bacterial adaptation.
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Cites
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Bacteriophage adhering to mucus provide a non–host-derived immunity
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Lysogeny in nature: mechanisms, impact and ecology of temperate phages
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Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms
Turnbull, L., Toyofuku, M., Hynen, A. L., Kurosawa, M., Pessi, G., Petty, N. K., Osvath, S. R., Cárcamo-Oyarce, G., Gloag, E. S., Shimoni, R., et al. (2016) · Nature Communications · doi:10.1038/ncomms11220 · Cited by 709
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome
Nayfach, S., Páez-Espino, D., Call, L., Low, S. J., Sberro, H., Ivanova, N. N., Proal, A. D., Fischbach, M. A., Bhatt, A. S., Hugenholtz, P., et al. (2021) · Nature Microbiology · doi:10.1038/s41564-021-00928-6 · Cited by 580
The Ecology and Evolution of Pangenomes
Brockhurst, M. A., Harrison, E., Hall, J. P. J., Richards, T., McNally, A., & MacLean, C. (2019) · Current Biology · doi:10.1016/j.cub.2019.08.012 · Cited by 385
Metadata
- Authors
- Bobay, L.-M., Touchon, M., & Rocha, E. P. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-08-04
- Volume
- 111
- Issue
- 33
- Pages
- 12127-12132
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2146966776
- Cited by
- 384
- References
- 48
- FWCI
- 16.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Bobay, L.-M., Touchon, M., & Rocha, E. P. C. (2014). Pervasive domestication of defective prophages by bacteria. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1405336111
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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