The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
A family of starch-active polysaccharide monooxygenases
Open accessAbstract
Significance: Polysaccharide monooxygenases (PMOs) are recently discovered extracellular fungal and bacterial enzymes that are able to cleave the recalcitrant polysaccharides cellulose and chitin. We describe the discovery of a new family of fungal PMOs that act on starch based on bioinformatic, biochemical, and spectroscopic studies on NCU8746, a representative starch-active PMO from Neurospora crassa . The data support a proposed enzymatic mechanism and show that NCU08746 shares evolutionarily conserved features with previously reported PMOs. This discovery extends the currently known PMO family, suggesting the existence of a PMO superfamily with a much broader range of substrates. Starch-active PMOs provide an expanded perspective on studies of starch metabolism and may have potential in the food and starch-based biofuel industries.
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Cited by
Payne, C. M., Knott, B. C., Mayes, H. B., Hansson, H., Himmel, M. E., Sandgren, M., Ståhlberg, J., & Beckham, G. T. (2015) · Chemical Reviews · doi:10.1021/cr500351c · Cited by 855
Lytic Polysaccharide Monooxygenases in Biomass Conversion
Hemsworth, G. R., Johnston, E. M., Davies, G. J., & Walton, P. H. (2015) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.09.006 · Cited by 314
Metadata
- Authors
- Vu, V. V., Beeson, W. T., Span, E. A., Farquhar, E. R., & Marletta, M. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-09-08
- Volume
- 111
- Issue
- 38
- Pages
- 13822-13827
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2005984466
- Cited by
- 275
- References
- 36
- FWCI
- 20.91
- Type
- journal article
- Language
- en
- Open access
- green
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