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MeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation

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Rett syndrome: advances in Understanding MeCP2 function, potential gene therapies, and public health implications

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The Role of DNA Methylation in Zebrafish Models of CNS Diseases

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MeCP2 goes into unmethylated territories

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GABA B receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation

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IRSF 2023 - Rett Syndrome Scientific Meeting Report

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Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome

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Structural, electronic and energetic consequences of epigenetic cytosine modifications

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Two sides of the same coin: NEO‐PUFAs in Rett syndrome and post‐infarction cardiac arrhythmias

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NUCOME: A comprehensive database of nucleosome organization referenced landscapes in mammalian genomes

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A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2

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MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisationPreprint

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Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1

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MECP2 mutations rewire human ESC fate and bias cortical lineage commitment

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Mechanistic Links Between DNA Methylation and Protein Translation and Their Impacts on Brain Development

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Whole Genome DNA Methylation Profiling of D2 Medium Spiny Neurons in Mouse Nucleus Accumbens Using Two Independent Library Preparation Methods

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Epigenomic Measurements in Brain Tissues

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Staphylococcus aureus α-hemolysin induces DNA methylation changes in human Th1 cells

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Driver or Passenger: Epigenomes in Alzheimer’s Disease

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Epigenetics in Intellectual Disability

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Genetic and epigenetic influences on the phenotype of Rett syndrome

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A Computational Approach to Identify Novel Protein Targets Uncovers New Potential Mechanisms of Action of Mirtazapine S (+) and R (−) Enantiomers in Rett Syndrome

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DNA methylation, nucleic acid structure, and rett mutations tune MeCP2 binding affinity and cooperativity

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Human MeCP2 binds to promoters and inhibits transcription in an unmethylated yeast genome

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Bisphosphonates and MeCP2 Deficiency: Cellular Studies and Clinical Application in Rett Syndrome

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Human MeCP2 binds to promoters and inhibits transcription in an unmethylated S. cerevisiae genomePreprint

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Role of MeCP2 in pain and its regulation by miRNAs

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Beyond mCG

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Intervention to Extrasynaptic Gabaa Receptors for Symptom Relief in Mouse Models of Rett Syndrome

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NUCOME : A Comprehensive Database of Nucleosome Organizations in Mammalian GenomesPreprint

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A genome-wide analysis reveals the MeCP2-dependent regulation of genes in BGC-823 cells.

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Transcriptomic and epigenetic changes after the phenotypic rescue of a Rett Syndrome mouse model

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Understanding the Roles of DNA Methylation and MeCP2 in Neuronal Enhancer Control

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Epigenomic Measurements in Brain Tissues

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Introducing, OncoTarget

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Faculty Opinions recommendation of Cerebral organoids recapitulate epigenomic signatures of the human fetal brain.

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Faculty Opinions recommendation of Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome.

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Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18942

Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18953

An overview of Rett syndrome

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Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18940

Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18794

Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18944

Introducing, OncoTarget

Blagosklonny, M. V., & Gudkov, A. V. (2010) · Oncotarget · doi:10.18632/oncotarget.18938

MECP2 duplication syndrome initially misdiagnosed as cerebral palsy: a case report

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Epigenetics and human disease

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An overview of Rett syndrome

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The Role of DNA Methylation in Zebrafish Models of CNS Diseases

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Transduction of hematopoietic stem and progenitor cells by an MECP2 lentiviral vector improves Rett syndrome phenotypes

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Dysfunction of a SET3-like complex underlies a family of related neurological disorders

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DNA Methylation: A Potential Mediator of the Memory Regulatory Effects of taVNS

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Exploring Single-Cell Gene Regulatory Dynamics in Rett SyndromePreprint

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Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes

Rylaarsdam, L. E., Skubi, B. W., Nichols, R. V., O’Connell, B. L., Kotnik, J. H., Coleman, S. D., Yardımcı, G. G., & Adey, A. (2025) · Communications Biology · doi:10.1038/s42003-025-08859-2 · Cited by 3

Biochemical Diagnosis in Substance and Non-substance Addiction

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Additional file 1 of NUCOME: A comprehensive database of nucleosome organization referenced landscapes in mammalian genomes

Chen, X., Yang, H., Liu, G., & Zhang, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14776523

Additional file 1 of MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data

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Additional file 3 of MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data

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Additional file 1 of Integrative modeling of lncRNA-chromatin interaction maps reveals diverse mechanisms of nuclear retention

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Additional file 2 of MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data

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Additional file 4 of MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data

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IGF1 peptide targets Rett Syndrome astrocytes to degrade IGF binding protein, rescue synaptogenesis and restore mitochondrial functionPreprint

Ojha, P., Kozareva, V., Barlowe, A. R., Schulte, F., Lam, R. M., Tomasello, D. L., Fraenkel, E., Jaenisch, R., & Sur, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.22.701190

Development of targeted methylome modifications in mammal cells

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Syndrome de Rett et implication des organes périphériques : de la physiopathologie à la thérapie

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Early postnatal DNA methylation dynamics define neuronal subtypes and are disrupted by MECP2 lossPreprint

Rylaarsdam, L. E., Nichols, R. V., O’Connell, B. L., Kragness, S., Yung, J. F., Saunders, A. B., Mandel, G., & Adey, A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.06.730504

Heat shock factor 1 signaling: A novel pathway implicated in Rett syndrome pathophysiology

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MECP2 -mutant marmosets exhibit primate-specific phenotypes of Rett syndromePreprint

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