The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index; none of the 19 sources its claims cite is checked for support yet.
Four-dimensional maps of the human somatosensory system
Open accessAbstract
Significance: Here, we show how anatomical and functional data recorded from patients undergoing stereo-EEG can be combined to generate highly resolved four-dimensional maps of human cortical processing. We used this technique, which provides spatial maps of the active cortical nodes at a millisecond scale, to depict the somatosensory processing following electrical stimulation of the median nerve in nearly 100 patients. The results showed that human somatosensory system encompasses a widespread cortical network including a phasic component, centered on primary somatosensory cortex and neighboring motor, premotor, and inferior parietal regions, as well as a tonic component, centered on the opercular and insular areas, lasting more than 200 ms.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
28 Own result · 16 Not checked yet · 11 Own method · 6 Own interpretation
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“High proportions of responsive leads were observed in the motor system, including the primary motor area (maximum values around 85%), large sectors of dorsal and ventral premotor cortex, and SMA.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The prolonged cluster (green palette) was restricted to a small sector of dorsal premotor area bilaterally (both reaching 33%), area 4 in the right hemisphere and SMA in the left hemisphere.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
None of the sources cited for this claim have been checked yet.
In the paper
“As shown in Fig. 3 A-C, the strong phasic cluster (see red palette) covered the middle strip of primary somatosensory areas (peaks of 81% in left 3b and 70% in right 3a), primary motor area and anterior part of inferior parietal cortex, corresponding to the caudal sectors of PF, PFt, and PFm (24,25).”
§ Four-dimensional maps of the human somatosensory system > Results
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“It is worth noting that half of the leads recorded in the present study by sEEG were localized in sulci, including major sulci for somatosensory processing like the sylvian and the rolandic fissures.”
§ Four-dimensional maps of the human somatosensory system > Discussion
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The tonic cluster (see blue palette) was highly specific for secondary somatosensory areas (OP1 and OP2) and long gyri of insular cortex (peaks around 80% and 90%).”
§ Four-dimensional maps of the human somatosensory system > Results
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“This network includes phasic components, centered on primary somatosensory cortex and neighboring motor, premotor, and inferior parietal regions, and tonic components, centered on opercular and insular areas, and involving human parietal rostroventral area and ventral medial-superior-temporal area.”
plaincorrelationaln = 100- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Statistical analysis revealed that 1,146 of the leads exploring gray matter presented a significant broadband gamma power (50-to 150-Hz) increase (see Fig. 1C for an example of single lead analysis on gamma-band time course) in response to the median nerve stimulation (489 in the left hemisphere, 657 in the right; Fig. S4).”
§ Four-dimensional maps of the human somatosensory system > Results
plaindirectSingle case ·- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Indeed, beside primary somatosensory cortices and SII/insula region (39), we revealed the activation of motor and premotor cortex (13), SMA (10, 40), superior and inferior parietal lobules (12,41,42).”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Clustering (k means) the time course of gamma band activity (Table S2) over all responsive leads indicated five to be the optimal number of clusters (average silhouette value: 0.448).”
§ Four-dimensional maps of the human somatosensory system > Results
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A prolonged cluster (green line) exhibited a similar time course in the rising phase, but persisted two time bins (20 ms) longer than phasic clusters.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
- It may state two separate claims as one. 35
- The quote only partly states this claim. 4
- Probably not a substantial claim. 19
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In particular, the highest proportion of responsive leads was present bilaterally in areas 3a (left 81%, right 94%) and 3b (left 95%, right 87%).Lower values characterized areas 1 (left 60%, right 60%) and 2 (left 55%, right 64%).”
§ Four-dimensional maps of the human somatosensory system > Results
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Also, activity in human PR, ventral premotor cortex (bilaterally), and MT cluster (right hemisphere) exhibited a tonic time course.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Interestingly, our findings distinguished different patterns of activation in peri-sylvian areas, with OP1 presenting the strongest phasic component followed by a tonic pattern, and OP2, OP3, and OP4 exhibiting mainly tonic activity (Fig. 4C).”
§ Four-dimensional maps of the human somatosensory system > Four-Dimensional Maps Provide Previously Unidentified Information About Interareal Dynamics.
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The ROI-by-time interaction again reached significance [F(4,236) = 1.294;P < 0.005] with subthreshold stimulation.Post hoc analysis, comparing mean gamma power across ROIs in the 50-to 70-ms time window confirmed the prolonged activation in motor and premotor areas relative to phAIP (Fig. S6).”
§ Four-dimensional maps of the human somatosensory system > Results
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Responsive regions included mainly OP1, OP2, and the long gyri of insular cortex (LgI), with both LgI active in the right hemisphere and the posterior LgI active in the left hemisphere.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The same analysis conducted on areas of the motor system (Fig. 4B) showed significant main effects for both time and ROIs, and a significant ROI-by-time interaction [F(4,236) = 6.545;P < 0.0001].”
§ Four-dimensional maps of the human somatosensory system > Results
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one. The quote only partly states this claim.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
In the paper
“In addition, two additional regions were identified as responding to median nerve stimulation.The first is located in both hemispheres in the same sector of parieto-ventral region that has been called human PR (19).”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
What the sources say
- Not checked yetcites [19] source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one. The quote only partly states this claim.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The region of interest (ROI) analysis confirmed that all four primary somatosensory areas are characterized by a strong-phasic time course, with areas 3a, 3b, and 1 similar in terms of peak amplitude (Fig. 4A).”
§ Four-dimensional maps of the human somatosensory system > Results
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
In the paper
“Opercular (OP) and insular regions were active in both hemispheres, peaking at 50% in OP1 (17).”
§ Four-dimensional maps of the human somatosensory system > Results
What the sources say
- Not checked yetcites [17] source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A completely different pattern was shown by a tonic cluster (blue line) lasting more than 200 ms, whose peak was consistently lower and later than all other clusters.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The centroids obtained for each cluster (Fig. 3B) depicted three synchronous patterns (strong-, middle-, and weak-phasic), characterized by a steep rise after stimulus delivery, a peak in the third time bin (20-30 ms) and a return to baseline level within 50 ms from stimulation.”
§ Four-dimensional maps of the human somatosensory system > Results
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Average (±SE) time course of leads in somatosensory areas (A), motor regions (B), and opercular/insular areas (C).Areas are listed (Insets).Black marks under the curves indicate significant post hoc comparisons (P < 0.002).Number of responsive leads for each graph: 34 in area 1, 54 in area 2, 21 in area 3a, 50 in area 3b (A); 68 in area 4, 157 in PMd, 45 in medial premotor areas, 42 in PMv, and 28”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Time courses (centroid ± SD) of the five clusters, as indicated (Inset).(Left and Right) Relative responsiveness (leads belonging to one cluster as a percentage of total number of responsive leads per disk) maps of left (L) and right (R) hemispheres (middle portion) for strong-phasic (yellow red), delayed-phasic (green), and tonic (blue) clusters.Only nodes with values exceeding 20% are shown.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Overall responsiveness (responsive leads as a percentage of total explored leads per disk) maps for the left (A) and right (B) hemispheres.Only surface nodes with values exceeding 10% were shown.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Average time frequency plot (100 trials) in response to median nerve stimulation in one lead of one patient.(C, Lower) Time course of the average gamma power (50-150 Hz) for the same channel, reported as z scores based on the prestimulus interval.Black asterisks indicate time bins with gamma power significantly exceeding baseline (P < 0.001).”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plainSingle case- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In 87 patients, the ROIs were devoid of any IED.In the remaining 12 patients, sparse IEDs were recorded during the stimulation protocol.”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
plainn = 87- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Four weighted amplitude maps of the left hemisphere at time bins indicated.The color range is dynamically adjusted from frame to frame.Note how the activity peaks in primary sensory areas in first frame, spreads to dorsal premotor area (second frame), remains active longer (third frame), whereas residual activity after 100 ms is recorded mostly from parietal operculum (OP1) and long gyri of insula”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Finally, our data showed that insular cortex was consistently activated by median nerve stimulation and presented a markedly tonic time course (Fig. 3).This activation was limited to the posterior part of insula, anatomically corresponding to the insular long gyri.”
§ Four-dimensional maps of the human somatosensory system > Four-Dimensional Maps Provide Previously Unidentified Information About Interareal Dynamics.
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
In the paper
“Disbrow et al. (18) reported that human PR responded to passive tactile stimulation, although in only 60% of tested participants.”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
What the sources say
- Not checked yetcites Disbrow et al. (18)
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“This area appears to be the counterpart of monkey PR, which is connected to IPL, area 4, and premotor cortex (19,43).”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“OP1 and OP4 [corresponding to areas S2 (secondary somatosensory area) and PV (parietal ventral area), as defined by Disbrow et al. (18)] are the main parts of classically defined SII.”
§ Four-dimensional maps of the human somatosensory system > Results
What the sources say
- Not checked yetcites Disbrow et al. (18)
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Investigating the temporal relationship between areas S2 and PR using MEG, Hinkley et al. (44) concluded that both S2 and PR contribute to the somatomotor integration needed for manual exploration and object discrimination, with S2 activity preceding that of PR.”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
What the sources say
- Not checked yetcites Hinkley et al. (44)
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the present study, the phasic component in OP1 coincided in time with the phasic activity in SI, thus favoring the view of a parallel propagation of sensory information to the two areas.”
§ Four-dimensional maps of the human somatosensory system > Four-Dimensional Maps Provide Previously Unidentified Information About Interareal Dynamics.
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
In the paper
“Given the high sensitivity of intracranial recordings, we were able to show that indeed somatosensory information reaches pMSTv, suggesting a possible integration between tactile and visual information (47).”
§ Four-dimensional maps of the human somatosensory system > Responsiveness Maps Document the Wide Extent of the Cortical
What the sources say
- Not checked yetcites [47] source
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
None of the sources cited for this claim have been checked yet.
In the paper
“High-frequency broadband gamma activity (50-150 Hz) was extracted from sEEG as an index of cortical activity, being spatially and functionally more specific than other frequency bands and presumably reflecting population spiking activity (36,37), and thus allowing networks to be investigated at millisecond time-scales (33).”
§ Four-dimensional maps of the human somatosensory system > Discussion
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“However, although useful for investigating activity from areas near the crowns of gyri, such recordings are blind to neuronal activity from deep regions (7).”
§ Four-dimensional maps of the human somatosensory system > Discussion
What the sources say
- Not checked yetcites [7] source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“In this step, single-lead representations were enhanced by arbitrarily adding six nodes (on the hexagonal mesh) surrounding the original single nodes on the native surfaces, to ensure that all leads in the individual surfaces were maintained on the template surface.”
§ Four-dimensional maps of the human somatosensory system > Median Nerve Stimulation.
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“To identify the leads responsive to median nerve stimulation, the gamma band power in each poststimulus bin was compared with baseline using a t test.Significance was Bonferroni corrected for 50 comparisons (P = 0.001), and to decrease the false-positive ratio, only leads with significant gamma increases in at least three time bins were designated as responsive.”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Only patients presenting with no anatomical alterations (n = 78) or with small abnormalities outside of the sensorimotor areas (n = 21), as evident on MR, were included.”
§ Four-dimensional maps of the human somatosensory system > Materials and Methods
plainn = 99- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
In the paper
“Nineteen clustering procedures were performed imposing increasing numbers of clusters (3-20) and computing silhouette values (75) to evaluate clustering validity.The optimal clustering was defined by the maximal average silhouette value, and leads with negative silhouette values were not considered in the evaluation of the optimal clustering using a repeated-measurement ANOVA with time and cluster”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
What the sources say
- Not checked yetcites [75] source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“No seizure occurred, no alterations in the sleep/wake cycle were observed, and no additional pharmacological treatments were applied during the 24 h before the experimental recording.”
§ Four-dimensional maps of the human somatosensory system > Materials and Methods
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“In these cases, however, false-positive responses are very unlikely because none of the patients included showed reflex IEDs, and thus IEDs were not synchronized to the stimulus.This absence was confirmed by visual inspection of the quality of the data averaged.”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
hedgedn = 12- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“This time-independent variable provides an overall picture of the cortical responsiveness, ranging from 0% to 100%, directly comparable to neuroimaging studies.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Given the fixed number of nodes representing a lead ( 7), this variable is equivalent to the number of responsive leads as a percent of the number of explored leads within a disk.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The reference was computed as the average of two adjacent leads both exploring white matter.These leads were selected time-by-time because they did not present any response to standard clinical stimulations, including somatosensory (median, tibial, and trigeminal nerves), visual (flash), and acoustical (click) stimulations.Nor did the leads' electrical stimulation evoke any sensory and/or motor”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Neurological examination was unremarkable in all cases; in particular, no motor or sensory deficit was found in any patient.”
§ Four-dimensional maps of the human somatosensory system > Materials and Methods
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“To quantify the goodness of fit between the native meshes and the template, we computed two local indices [i.e., deformation and distortion, evaluated for each node of the mesh (72)], indexing the shrinkage and translation of each node during the transformation.”
§ Four-dimensional maps of the human somatosensory system > Median Nerve Stimulation.
What the sources say
- Not checked yetcites [72] source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Finally, to compare cortical areas, leads were grouped by their location in a ROI-based analysis to evaluate differences among primary sensory areas (3a, 3b, 1, and 2), motor areas (4, medial premotor area, PMd, PMv, and phAIP), and the secondary somatosensory areas (OP1, OP2, OP3, OP4, and LgI).These ROIs were defined either by cytoarchitectonical or functional criteria (see Continuous Maps).For”
§ Four-dimensional maps of the human somatosensory system > SEEG Data Recording and Processing.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one. The quote only partly states this claim.
In the paper
“To provide a continuous view of the topographic pattern of active leads, we built a circular mask based on the geodesic distance between two cortical points (76) (i.e., the minimum pathway within the gray matter connecting the source and the target nodes).For each cortical node, we defined the nodes within a 1-cm geodesic distance from the original node and weighted the contribution of each node”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
What the sources say
- Not checked yetcites [76] source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one. The quote only partly states this claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“This variable indexes the degree to which an area responds with a specific temporal pattern, information to which neuroimaging studies are completely blind.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
The paper relies on this without support.
The cortical somatosensory organization observed in these patients with drug-resistant focal epilepsy is representative of the healthy human somatosensory system.
“Stereo-EEG data were collected from 99 patients (52 male, 47 female) suffering from drug-resistant focal epilepsy.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Human intracerebral (stereo-EEG) recordings led to the identification of tonic activity patterns, 41 i.e., prolonged low-amplitude gamma-band responses to sensory stimulation, likely corresponding to the intracranial correlate of previously reported late EEG components reflecting perceptual awareness.42,43”
From An integrative, multiscale view on neural theories of consciousness (2024) · cites this paper as [41]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
“the leads numbered 1-18 from the tip, for a total distance of 50 mm.”
§ Four-dimensional maps of the human somatosensory system > Electrode Implantation.
“Each cylindrical electrode had a diameter of 0.8 mm and consisted of eight to eighteen 2-mm-long contacts (leads), spaced 1.5 mm apart”
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Four-dimensional maps of the human somatosensory system > Discussion
“Of note, masks centered at 1.5-cm geodesic distance were completely independent, having no shared nodes.”
§ Four-dimensional maps of the human somatosensory system > Continuous Maps.
“For each cortical node, we defined the nodes within a 1-cm geodesic distance from the original node”
Citations
Cites
Silhouettes: A graphical aid to the interpretation and validation of cluster analysis
Rousseeuw, P. J. (1987) · Journal of Computational and Applied Mathematics · doi:10.1016/0377-0427(87)90125-7 · Cited by 21,392
Cortical Surface-Based Analysis
Dale, A. M., Fischl, B., & Sereno, M. I. (1999) · NeuroImage · doi:10.1006/nimg.1998.0395 · Cited by 10,910
3D Slicer as an image computing platform for the Quantitative Imaging Network
Fedorov, A., Beichel, R., Kalpathy–Cramer, J., Finet, J., Fillion‐Robin, J., Pujol, S., Bauer, C., Jennings, D. L., Fennessy, F., Milan Sonka, A., et al. (2012) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2012.05.001 · Cited by 9,095
A global optimisation method for robust affine registration of brain images
Jenkinson, M., & Smith, S. M. (2001) · Medical Image Analysis · doi:10.1016/s1361-8415(01)00036-6 · Cited by 7,018
Mesulam, M. (1998) · Brain · doi:10.1093/brain/121.6.1013 · Cited by 3,072
Within-subject template estimation for unbiased longitudinal image analysis
Reuter, M., Schmansky, N. J., Rosas, H. D., & Fischl, B. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.02.084 · Cited by 2,356
Kurth, F., Zilles, K., Fox, P. T., Laird, A. R., & Eickhoff, S. B. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0255-z · Cited by 1,293
Different Origins of Gamma Rhythm and High-Gamma Activity in Macaque Visual Cortex
Ray, S., & Maunsell, J. H. R. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1000610 · Cited by 1,012
CONNEXIONS OF THE SOMATIC SENSORY CORTEX OF THE RHESUS MONKEY
Jones, E. G., & Powell, T. P. S. (1969) · Brain · doi:10.1093/brain/92.3.477 · Cited by 659
Newsome, W. T., Wurtz, R. H., & Komatsu, H. (1988) · Journal of Neurophysiology · doi:10.1152/jn.1988.60.2.604 · Cited by 649
Cited by
Sorted by citations
Motor and emotional behaviours elicited by electrical stimulation of the human cingulate cortex
Caruana, F., Gerbella, M., Avanzini, P., Gozzo, F., Pelliccia, V., Mai, R., Abdollahi, R. O., Cardinale, F., Sartori, I., Russo, G. L., et al. (2018) · Brain · doi:10.1093/brain/awy219 · Cited by 278
Self-citationAdvances in human intracranial electroencephalography research, guidelines and good practices
Mercier, M. R., Dubarry, A., Tadel, F., Avanzini, P., Axmacher, N., Cellier, D., Vecchio, M. D., Hamilton, L. S., Hermes, D., Kahana, M. J., et al. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119438 · Cited by 254
Self-citationGrivaz, P., Blanke, O., & Serino, A. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2016.12.052 · Cited by 203
Neuromuscular electrical stimulation‐promoted plasticity of the human brain
Carson, R. G., & Buick, A. R. (2019) · The Journal of Physiology · doi:10.1113/jp278298 · Cited by 149
An integrative, multiscale view on neural theories of consciousness
Storm, J. F., Klink, P. C., Aru, J., Senn, W., Goebel, R., Pigorini, A., Avanzini, P., Vanduffel, W., Roelfsema, P. R., Massimini, M., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.02.004 · Cited by 114
“Human intracerebral (stereo-EEG) recordings led to the identification of tonic activity patterns, 41 i.e., prolonged low-amplitude gamma-band responses to sensory stimulation, likely corresponding to the intracranial correlate of previously reported late EEG components reflecting perceptual awareness.”
Self-citationAnalysis of haptic information in the cerebral cortex
Sathian, K. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00546.2015 · Cited by 96
Functional definitions of parietal areas in human and non-human primates
Orban, G. A. (2016) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2016.0118 · Cited by 97
Self-citationSaliency Detection as a Reactive Process: Unexpected Sensory Events Evoke Corticomuscular Coupling
Novembre, G., Pawar, V., Bufacchi, R. J., Kilintari, M., Srinivasan, M. A., Rothwell, J. C., Haggard, P., & Iannetti, G. D. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.2474-17.2017 · Cited by 93
SEEG assistant: a 3DSlicer extension to support epilepsy surgery
Narizzano, M., Arnulfo, G., Ricci, S., Toselli, B., Tisdall, M. M., Canessa, A., Fato, M., & Cardinale, F. (2017) · BMC Bioinformatics · doi:10.1186/s12859-017-1545-8 · Cited by 94
Pothof, F., Bonini, L., Lanzilotto, M., Livi, A., Fogassi, L., Orban, G. A., Paul, O., & Ruther, P. (2016) · Journal of Neural Engineering · doi:10.1088/1741-2560/13/4/046006 · Cited by 56
Self-citationData-driven re-referencing of intracranial EEG based on independent component analysis (ICA)
Michelmann, S., Treder, M. S., Griffiths, B. J., Kerrén, C., Roux, F., Wimber, M., Rollings, D. T., Sawlani, V., Chelvarajah, R., Gollwitzer, S., et al. (2018) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2018.06.021 · Cited by 56
Lamp, G., Goodin, P., Palmer, S., Low, E., Barutchu, A., & Carey, L. M. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2018.01129 · Cited by 55
Smile and laughter elicited by electrical stimulation of the frontal operculum
Caruana, F., Gozzo, F., Pelliccia, V., Cossu, M., & Avanzini, P. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.07.001 · Cited by 51
Self-citationA mirror mechanism for smiling in the anterior cingulate cortex.
Caruana, F., Avanzini, P., Gozzo, F., Pelliccia, V., Casaceli, G., & Rizzolatti, G. (2016) · Emotion · doi:10.1037/emo0000237 · Cited by 51
Self-citationMultiple time courses of somatosensory responses in human cortex
Avanzini, P., Pelliccia, V., Lo Russo, G., Orban, G. A., & Rizzolatti, G. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2017.12.037 · Cited by 49
Self-citationPelliccia, V., Avanzini, P., Rizzi, M., Caruana, F., Tassi, L., Francione, S., Gozzo, F., Mariani, V., d’Orio, P., Castana, L., et al. (2022) · Neurology · doi:10.1212/wnl.0000000000200145 · Cited by 44
Self-citationNeural surprise in somatosensory Bayesian learning
Gijsen, S., Grundei, M., Lange, R. T., Ostwald, D., & Blankenburg, F. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008068 · Cited by 43
Goodin, P., Lamp, G., Vidyasagar, R., McArdle, D. J. T., Seitz, R. J., & Carey, L. M. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.02.012 · Cited by 43
Ryun, S., Kim, J. S., Lee, H., & Chung, C. K. (2017) · Scientific Reports · doi:10.1038/s41598-017-15767-x · Cited by 39
The neural underpinnings of haptically guided functional grasping of tools: An fMRI study
Styrkowiec, P., Nowik, A. M., & Króliczak, G. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.03.043 · Cited by 39
Proctor, R. W., & Proctor, J. D. (2006) · doi:10.1002/0470048204.ch3 · Cited by 38
Caruana, F., Avanzini, P., Pelliccia, V., Mariani, V., Zauli, F. M., Sartori, I., Vecchio, M. D., Russo, G. L., & Rizzolatti, G. (2020) · Cortex · doi:10.1016/j.cortex.2020.02.023 · Cited by 36
Self-citationMultilevel Cortical Processing of Somatosensory Novelty: A Magnetoencephalography Study
Naeije, G., Thibaut, V., Wens, V., Marty, B., Goldman, S., & Tiège, X. D. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00259 · Cited by 41
Egomotion‐related visual areas respond to active leg movements
Serra, C., Galletti, C., Marco, S. D., Fattori, P., Galati, G., Sulpizio, V., & Pitzalis, S. (2019) · Human Brain Mapping · doi:10.1002/hbm.24589 · Cited by 33
Human stereoEEG recordings reveal network dynamics of decision-making in a rule-switching task
Wal, M. T., Platonov, A., Cardellicchio, P., Pelliccia, V., Russo, G. L., Sartori, I., Avanzini, P., Orban, G. A., & Tiesinga, P. H. E. (2020) · Nature Communications · doi:10.1038/s41467-020-16854-w · Cited by 36
Self-citationLi, G., Jiang, S., Chen, C., Brunner, P., Wu, Z., Schalk, G., Chen, L., & Zhang, D. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab51a5 · Cited by 34
Volta, R. D., Avanzini, P., Marco, D. D., Gentilucci, M., & Fabbri‐Destro, M. (2017) · Cortex · doi:10.1016/j.cortex.2017.09.012 · Cited by 32
Self-citationProctor, R. W., & Proctor, J. D. (2021) · Wiley eBooks · doi:10.1002/9781119636113.ch3 · Cited by 32
Dynamic spatial coding in parietal cortex mediates tactile-motor transformation
Klautke, J., Foster, C., Medendorp, W. P., & Heed, T. (2023) · Nature Communications · doi:10.1038/s41467-023-39959-4 · Cited by 27
Tonic somatosensory responses and deficits of tactile awareness converge in the parietal operculum
Del Vecchio, M., Fossataro, C., Zauli, F. M., Sartori, I., Pigorini, A., d’Orio, P., Abarrategui, B., Russo, S., Mikulan, E. P., Caruana, F., et al. (2021) · Brain · doi:10.1093/brain/awab384 · Cited by 26
Self-citationAnatomo-functional basis of emotional and motor resonance elicited by facial expressions
Vecchio, M. D., Avanzini, P., Gerbella, M., Costa, S. E., Zauli, F. M., d’Orio, P., Focacci, E., Sartori, I., & Caruana, F. (2024) · Brain · doi:10.1093/brain/awae050 · Cited by 29
Self-citationPrefrontal and posterior parietal contributions to the perceptual awareness of touch
Rullmann, M., Preusser, S., & Pleger, B. (2019) · Scientific Reports · doi:10.1038/s41598-019-53637-w · Cited by 26
Chandrasekaran, S., Bickel, S., Herrero, J. L., Kim, J.-W., Markowitz, N., Espinal, E., Bhagat, N. A., Ramdeo, R., Xu, J., Glasser, M. F., et al. (2021) · Brain stimulation · doi:10.1016/j.brs.2021.07.009 · Cited by 26
Zauli, F. M., Vecchio, M. D., Russo, S., Mariani, V., Pelliccia, V., d’Orio, P., Sartori, I., Avanzini, P., & Caruana, F. (2022) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2021.0180 · Cited by 26
Self-citationFiáth, R., Hofer, K. T., Csikós, V., Horváth, D., Nánási, T., Tóth, K., Pothof, F., Böhler, C., Asplund, M., Ruther, P., et al. (2018) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt-2017-0154 · Cited by 25
Del Vecchio, M., Caruana, F., Sartori, I., Pelliccia, V., Lo Russo, G., Rizzolatti, G., & Avanzini, P. (2019) · Brain Structure and Function · doi:10.1007/s00429-018-1754-6 · Cited by 23
Self-citationSystem neuroscience: Past, present, and future
Rizzolatti, G., Fabbri‐Destro, M., Caruana, F., & Avanzini, P. (2018) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12997 · Cited by 25
Self-citationLesourd, M., Osiurak, F., Navarro, J., & Reynaud, E. (2017) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000455 · Cited by 22
Li, G., Jiang, S., Paraskevopoulou, S. E., Chai, G., Wei, Z., Liu, S., Wang, M., Yang, X., Fan, Z., Wu, Z., et al. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac160e · Cited by 22
Vecchio, M. D., Caruana, F., Sartori, I., Pelliccia, V., Zauli, F. M., Russo, G. L., Rizzolatti, G., & Avanzini, P. (2020) · Communications Biology · doi:10.1038/s42003-020-0793-8 · Cited by 25
Self-citationHigh gamma response tracks different syntactic structures in homophonous phrases
Artoni, F., d’Orio, P., Catricalà, E., Conca, F., Bottoni, F., Pelliccia, V., Sartori, I., Russo, G. L., Cappa, S. F., Micera, S., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-64375-9 · Cited by 26
Self-citationDecomposing Tool-Action Observation: A Stereo-EEG Study
Caruana, F., Avanzini, P., Mai, R., Pelliccia, V., Russo, G. L., Rizzolatti, G., & Orban, G. A. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx124 · Cited by 20
Self-citationFornia, L., Rossi, M., Rabuffetti, M., Bellacicca, A., Viganò, L., Simone, L., Howells, H., Puglisi, G., Leonetti, A., Callipo, V., et al. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118839 · Cited by 19
Movement-Related Sensorimotor High-Gamma Activity Mainly Represents Somatosensory Feedback
Ryun, S., Kim, J. S., Jeon, E., & Chung, C. K. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00408 · Cited by 19
Epileptogenic Network Formation
Palma, L. D., BENEDICTIS, A. D., Specchio, N., & Marras, C. E. (2020) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2020.03.012 · Cited by 19
Fossataro, C., Bruno, V., Bosso, E., Chiotti, V., Gindri, P., Farnè, A., & Garbarini, F. (2020) · Cortex · doi:10.1016/j.cortex.2020.02.004 · Cited by 17
Cortical maps of somatosensory perception in human
Ryun, S., Kim, M., Kim, J. S., & Chung, C. K. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120197 · Cited by 17
Naeije, G., Wens, V., Bourguignon, M., Goldman, S., Pandolfo, M., & Tiège, X. D. (2019) · Clinical Neurophysiology · doi:10.1016/j.clinph.2019.05.003 · Cited by 17
Pigorini, A., Avanzini, P., Barborică, A., Bénar, C., Olivier David, A., Farisco, M., Keller, C. J., Manfridi, A., Mikulan, E., Paulk, A. C., et al. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110160 · Cited by 16
Self-citationConscious tactile perception entails distinct neural dynamics within somatosensory areas
Albertini, D., Vecchio, M. D., Sartori, I., Pigorini, A., Talami, F., Zauli, F. M., Sarasso, S., Mikulan, E., Massimini, M., & Avanzini, P. (2025) · Current Biology · doi:10.1016/j.cub.2025.04.052 · Cited by 21
Self-citationRapid and specific processing of person-related information in human anterior temporal lobe
Platonov, A., Avanzini, P., Pelliccia, V., Russo, G. L., Sartori, I., & Orban, G. A. (2018) · Communications Biology · doi:10.1038/s42003-018-0250-0 · Cited by 14
Self-citationMuret, D., & Dinse, H. R. (2018) · Scientific Reports · doi:10.1038/s41598-018-30183-5 · Cited by 14
Sulpizio, V., Strappini, F., Fattori, P., Galati, G., Galletti, C., Pecchinenda, A., & Pitzalis, S. (2022) · Brain Structure and Function · doi:10.1007/s00429-022-02549-z · Cited by 12
Feeling Touched: Empathy Is Associated With Performance in a Tactile Acuity Task
Schaefer, M., Joch, M., & Rother, N. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.593425 · Cited by 13
Wang, M., Nikaido, K., Kim, Y., Ji, B., Tian, H., Kang, X., Yang, C., Yang, B., Chen, X., Wang, X., et al. (2017) · IEEE International Conference on Micro Electro Mechanical Systems (MEMS) · doi:10.1109/memsys.2017.7863453 · Cited by 12
Electrocorticography Evidence of Tactile Responses in Visual Cortices
Gaglianese, A., Branco, M. P., Groen, I. I. A., Benson, N. C., Vansteensel, M. J., Murray, M. M., Petridou, N., & Ramsey, N. F. (2020) · Brain Topography · doi:10.1007/s10548-020-00783-4 · Cited by 12
Dispositional empathy predicts primary somatosensory cortex activity while receiving touch by a hand
Schaefer, M., Kühnel, A., Rumpel, F., & Gärtner, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-90344-x · Cited by 12
Scano, A., Mira, R. M., Gabbrielli, G., Molteni, F., & Terekhov, V. I. (2022) · Sensors · doi:10.3390/s22041443 · Cited by 11
Tatti, E., Ferraioli, F., Cacciola, A., Chan, C., Quartarone, A., & Ghilardi, M. F. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.836703 · Cited by 12
Tiesinga, P. H. E., Platonov, A., Pelliccia, V., Russo, G. L., Sartori, I., & Orban, G. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-33318-5 · Cited by 10
Self-citationStereo-EEG recordings extend known distributions of canonical movement-related oscillations
Rockhill, A. P., Mantovani, A., Stedelin, B., Nerison, C. S., Raslan, A. M. T., & Swann, N. C. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/acae0a · Cited by 10
Kanno, A., Kochi, R., Sakakura, K., Kitazawa, Y., Uda, H., Ueda, R., Sonoda, M., Lee, M.-H., Jeong, J., Rothermel, R., et al. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121319 · Cited by 10
Characterization of network structure in stereoEEG data using consensus-based partial coherence
Wal, M. T., Cardellicchio, P., Russo, G. L., Pelliccia, V., Avanzini, P., Orban, G. A., & Tiesinga, P. H. E. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.06.011 · Cited by 7
Self-citationHenderson, J., Mari, T., Hewitt, D., Newton‐Fenner, A., Giesbrecht, T., Marshall, A., Stančák, A., & Fallon, N. B. (2023) · Brain and Behavior · doi:10.1002/brb3.3264 · Cited by 6
Xie, T., Wu, Z., Schalk, G., Tong, Y., Vato, A., Raviv, N., Guo, Q., Ye, H., Sheng, X., Zhu, X., et al. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac7dfd · Cited by 6
Altruistic acting caused by a touching hand: neural underpinnings of the Midas touch effect
Schaefer, M., Kühnel, A., Rumpel, F., & Gärtner, M. (2021) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsab119 · Cited by 6
Millisecond-Scale White Matter Dynamics Underlying Visuomotor Integration
Ueda, R., Uda, H., Hatano, K., Sakakura, K., Kuroda, N., Kitazawa, Y., Kanno, A., Lee, M.-H., Jeong, J.-W., Luat, A. F., et al. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121352 · Cited by 5
Language lateralization mapping (reversibly) masked by non-dominant focal epilepsy: a case report
Abarrategui, B., Mariani, V., Rizzi, M., Berta, L., Scarpa, P., Zauli, F. M., Squarza, S. A. C., Banfi, P., d’Orio, P., Cardinale, F., et al. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1254779 · Cited by 5
Self-citationThe neural networks of touch observation
Schaefer, M., Kuehn, E., Schweitzer, F. M., & Muehlhan, M. (2023) · Imaging Neuroscience · doi:10.1162/imag_a_00065 · Cited by 6
Introducing HiBoP: a Unity‐based visualization software for large iEEG datasets
Vecchio, M. D., Bontemps, B., Lance, F., Gannerie, A., Sipp, F., Albertini, D., Cassani, C. M., Chatard, B., Dupin, M., & Lachaux, J.-P. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110179 · Cited by 5
Have I Been Touched? Subjective and Objective Aspects of Tactile Awareness
Cirillo, E., Zavattaro, C., Gammeri, R., Serra, H., Ricci, R., & Berti, A. (2024) · Brain Sciences · doi:10.3390/brainsci14070653 · Cited by 5
Rizzi, M., Sartori, I., Maria, D. V., Berta, L., Lizio, D., Zauli, F. M., BENEDICTIS, A. D., Sarubbo, S., Khalid, A.-O., Mariani, V., et al. (2022) · Brain Structure and Function · doi:10.1007/s00429-021-02430-5 · Cited by 5
Self-citationMechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI
Gaglianese, A., Fracasso, A., Fernandes, F. G., Harvey, B. M., Dumoulin, S. O., & Petridou, N. (2023) · Human Brain Mapping · doi:10.1002/hbm.26193 · Cited by 6
Functional Connectivity Evoked by Orofacial Tactile Perception of Velocity
Wang, Y., Sibaii, F., Custead, R., Oh, H., & Barlow, S. M. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00182 · Cited by 5
Electrophysiological correlates of syntactic structuresPreprint
Artoni, F., d’Orio, P., Catricalà, E., Conca, F., Bottoni, F., Pelliccia, V., Sartori, I., Russo, G. L., Cappa, S. F., Micera, S., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/660415 · Cited by 5
Self-citationNeural surprise in somatosensory Bayesian learningPreprint
Gijsen, S., Grundei, M., Lange, R. T., Ostwald, D., & Blankenburg, F. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.18.158915 · Cited by 5
Scalp EEG predicts intracranial brain activity in humansPreprint
Subramanian, A. K., Talbot, A., Kim, N., Parmigiani, S., Cline, C. C., Solomon, E. A., Hartford, J. D., Huang, Y., Mikulan, E., Zauli, F. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.07.647612 · Cited by 6
Zhang, Q., Pang, Z., Lu, R., He, H., Ziemann, U., & Gao, Z. (2025) · Neural Plasticity · doi:10.1155/np/9100284 · Cited by 4
Bellacicca, A., Rossi, M., Viganò, L., Simone, L., Howells, H., Gambaretti, M., Gallotti, A., Leonetti, A., Puglisi, G., Talami, F., et al. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110177 · Cited by 4
Visualization of functional and effective connectivity underlying auditory descriptive naming
Kitazawa, Y., Sakakura, K., Uda, H., Kuroda, N., Ueda, R., Firestone, E., Lee, M.-H., Jeong, J., Sonoda, M., Osawa, S.-I., et al. (2025) · Clinical Neurophysiology · doi:10.1016/j.clinph.2025.04.008 · Cited by 4
Asman, P., Pellizzer, G., Tummala, S., Tasnim, I., Bastos, D. C. A., Bhavsar, S., Prabhu, S. S., & Ince, N. F. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.10.008 · Cited by 4
Spatio-temporal evolution of human neural activity during visually cued hand movements
Li, G., Jiang, S., Meng, J., Wu, Z., Jiang, H., Fan, Z., Hu, J. Z., Sheng, X., Zhang, D., Schalk, G., et al. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad242 · Cited by 4
Costa, S., Lomoriello, A. S., Quettier, T., Caruana, F., Ferrari, P. F., & Sessa, P. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121322 · Cited by 3
Self-citationKochi, R., Kanno, A., Uda, H., Hatano, K., Endo, H., Cools, M. J., Rothermel, R. D., Luat, A. F., & Asano, E. (2025) · Neurology · doi:10.1212/wnl.0000000000214448 · Cited by 3
Ryun, S., Kim, J. S., & Chung, C. K. (2021) · International Winter Conference on Brain-Computer Interface (BCI) · doi:10.1109/bci51272.2021.9385318 · Cited by 3
Vecchio, M. D., & Avanzini, P. (2020) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2020.597755 · Cited by 3
Self-citationAn intracranial insight into (the timing of) the action observation network
Vecchio, M. D., Caruana, F., Zauli, F. M., Pelliccia, V., Sartori, I., d’Orio, P., Talami, F., Sorbo, S. D., Albertini, D., Rizzolatti, G., et al. (2026) · NeuroImage · doi:10.1016/j.neuroimage.2026.121714 · Cited by 2
Self-citationMacroscopic Aspects of Bi-directional BCI in Human
Ryun, S., Yang, Y. J., Kwon, J., Kim, J. S., & Chung, C. K. (2020) · International Winter Conference on Brain-Computer Interface (BCI) · doi:10.1109/bci48061.2020.9061620 · Cited by 2
Janssens, S. E. W., de Graaf, T. A., Duecker, F., Schuhmann, T., & Sack, A. T. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.07.487517 · Cited by 2
High-frequency oscillation-calibrated short-latency afferent inhibition: A novel TMS protocol
Lanzone, J. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.09.014 · Cited by 2
Single and Multi-Site Cortical Stimulation Related to Human Sensorimotor FunctionPreprint
Ryun, S., & Chung, C. K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.18.574786 · Cited by 2
Spatio-temporal dynamics of sound-induced vestibular processing: insights from stereo-EEG recordings
Terzaghi, M., d’Orio, P., Sartori, I., Pelliccia, V., Zauli, F. M., Colnaghi, S., Rustioni, V., Caruana, F., Vecchio, M. D., Versino, M., et al. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121261 · Cited by 1
Self-citationCortical spectral dynamics of vibrotactile frequency processing
Rustamov, N., Demarest, P., Han, Z.-Y., Mohamud, S. F., Haroutounian, S., & Leuthardt, E. (2025) · Scientific Reports · doi:10.1038/s41598-025-14870-8 · Cited by 3
A probabilistic map of motor and cognitive functions: a meta-analysis of 4325 stimulation sites
Alexandratou, A., Sefcikova, V., Elmalem, M. S., Bisschop, J., Huet, S., Samandouras, G., & Nachev, P. (2025) · Brain Structure and Function · doi:10.1007/s00429-025-03015-2 · Cited by 1
Ryun, S., Lim, S., Jang, D. P., & Chung, C. K. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00159.2024 · Cited by 2
A Review on the Pathomechanism of Interictal Psychiatry Comorbidities in Epilepsy
SzAcs, A., Horvath, A. A., Fabó, D., Kovács, A., Halász, P., & Szabo, G. (2018) · Journal of Neurology and Neuroscience · doi:10.21767/2171-6625.1000244 · Cited by 1
We Three: My Brain, My Homunculus, and Me
Klemm, W. R. (2020) · Journal of Psychology & Behavior Research · doi:10.22158/jpbr.v2n1p16 · Cited by 1
Rizzolatti, G., Gerbella, M., & Rozzi, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.24235-1 · Cited by 3
Self-citationStereo-EEG reveals rich cortical dynamics in humans coping with difficult action discriminationPreprint
Platonov, A., Pelliccia, V., Sartori, I., Russo, G. L., Avanzini, P., & Orban, G. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.23.916569 · Cited by 1
Self-citationAn integrative, multiscale view on consciousness theories_Eary version of paper in press in NEURONPreprint
Storm, J. F., Klink, P. C., Aru, J., Senn, W., Goebel, R., Pigorini, A., Avanzini, P., Vanduffel, W., Roelfsema, P. R., Massimini, M., et al. (2024) · doi:10.31234/osf.io/9byzu · Cited by 1
Self-citation
Metadata
- Authors
- Avanzini, P., Abdollahi, R. O., Sartori, I., Caruana, F., Pelliccia, V., Casaceli, G., Mai, R., Lo Russo, G., Rizzolatti, G., & Orban, G. A.
- Affiliations
- University of Parma (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Italian Institute of Technology (IT)
- Centro per la chirurgia dell’Epilessia “Claudio Munari,” Ospedale Ca’Granda-Niguarda, 20162 Milan, Italy;
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2016-03-14
- Volume
- 113
- Issue
- 13
- Pages
- E1936-43
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4822602
- OpenAlex
- W2301449719
- Cited by
- 114
- References
- 82
- Citations by year
- 2026: 4 · 2025: 16 · 2024: 8 · 2023: 9 · 2022: 15 · 2021: 10 · 2020: 14 · 2019: 10 · 2018: 12 · 2017: 8 · 2016: 7
- FWCI
- 7.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- EC | European Research Council (250013, 323606)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- somatosensory system, primary somatosensory cortex, intracerebral recordings, insula, inferior parietal cortex, premotor cortex
- MeSH terms
- Drug Resistant Epilepsy, Brain Mapping, Cerebral Cortex, Electrodes, Implanted, Electroencephalography, Female, Humans, Image Processing, Computer-Assisted, Male, Models, Biological, Somatosensory Cortex, Magnetoencephalography, Cluster Analysis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
A language model drew the claims from the paper on 2026-10-07, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).
A second model labelled each claim on 2026-10-07 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
