Vitamin C increases viral mimicry induced by 5-aza-2′-deoxycytidine

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L., et al. (2009) · Science · doi:10.1126/science.1170116 · Cited by 5,836

Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies

Chou, T.-C. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.10 · Cited by 5,163

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

Snyder, A., Makarov, V., Merghoub, T., Yuan, J., Zaretsky, J. M., Desrichard, A., Walsh, L. A., Postow, M. A., Wong, P., Ho, T. S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1406498 · Cited by 4,286

Epigenetics in human disease and prospects for epigenetic therapy

Egger, G., Liang, G., Aparicio, A., & Jones, P. A. (2004) · Nature · doi:10.1038/nature02625 · Cited by 3,232

A decade of exploring the cancer epigenome—biological and translational implications

Baylin, S. B., & Jones, P. A. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3130 · Cited by 2,871

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

Fenaux, P., Mufti, G. J., Hellstrom-Lindberg, E., Santini, V., Finelli, C., Giagounidis, A., Schoch, R., Gattermann, N., Sanz, G., List, A., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70003-8 · Cited by 2,663

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

Chiappinelli, K. B., Strissel, P. L., Desrichard, A., Li, H., Henke, C., Akman, B., Hein, A., Rote, N. S., Cope, L. M., Snyder, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.011 · Cited by 2,022

Decitabine improves patient outcomes in myelodysplastic syndromes

Kantarjian, H. M., Issa, J. J., Rosenfeld, C. S., Bennett, J. M., Albitar, M. X., DiPersio, J. F., Klimek, V. M., Slack, J. L., de Castro, C., Ravandi, F., et al. (2006) · Cancer · doi:10.1002/cncr.21792 · Cited by 1,539

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

Roulois, D., Loo Yau, H., Singhania, R., Wang, Y., Danesh, A., Shen, S. Y., Han, H., Liang, G., Jones, P. A., Pugh, T. J., et al. (2015) · Cell · doi:10.1016/j.cell.2015.07.056 · Cited by 1,527

Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types

Topham, J. T., Titmuss, E., Pleasance, E., Williamson, L. M., Karasinska, J. M., Culibrk, L., Lee, M. K. C., Mendis, S. R., Denroche, R. E., Jang, G.-H., et al. (2020) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-20-0094 · Cited by 27

The Result of Vitamin C Treatment of Patients with Cancer: Conditions Influencing the Effectiveness

Hunyady, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084380 · Cited by 29

Human Endogenous Retrovirus K in the Crosstalk Between Cancer Cells Microenvironment and Plasticity: A New Perspective for Combination Therapy

Balestrieri, E., Argaw-Denboba, A., Gambacurta, A., Cipriani, C., Bei, R., Serafino, A., Vallebona, P. S., & Matteucci, C. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01448 · Cited by 24

Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy

Jung, I., An, J., & Ko, M. (2023) · Biomedicines · doi:10.3390/biomedicines11030654 · Cited by 22

Parenteral high‑dose ascorbate - A possible approach for the treatment of glioblastoma (Review)

Renner, O., Burkard, M., Michels, H., Vollbracht, C., Sinnberg, T. W., & Venturelli, S. (2021) · International Journal of Oncology · doi:10.3892/ijo.2021.5215 · Cited by 24

scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs

Hunt, K. V., Burnard, S. M., Roper, E. A., Bond, D. R., Dun, M. D., Verrills, N. M., Enjeti, A. K., & Lee, H. J. (2022) · Scientific Reports · doi:10.1038/s41598-022-09765-x · Cited by 23

Activation of viral defense signaling in cancer

González‐Cao, M., Karachaliou, N., Santarpía, M., Viteri, S., Meyerhans, A., & Rosell, R. (2018) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758835918793105 · Cited by 21

Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells

Son, E. S., Kim, S. H., Kim, Y. O., Lee, Y. E., Kyung, S. Y., Jeong, S. H., Kim, Y. J., & Park, J.-W. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2725-z · Cited by 20

Rewiring of chromatin state and gene expression by transposable elements

Ohtani, H., & Iwasaki, Y. W. (2021) · Development Growth & Differentiation · doi:10.1111/dgd.12735 · Cited by 23

Epigenetic Regulation in Uterine Fibroids—The Role of Ten-Eleven Translocation Enzymes and Their Potential Therapeutic Application

Włodarczyk, M., Nowicka, G., Ciebiera, M., Ali, M. K., Yang, Q., & Al-Hendy, A. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052720 · Cited by 19

DNA methylation in cell plasticity and malignant transformation in liver diseases

Kim, M., Delgado, E. R., & Ko, S. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108334 · Cited by 20

DNA methyltransferase inhibitors in hematological malignancies and solid tumors

Wenger, V., Garcia‐Manero, G., Zeiser, R., & Lübbert, M. (2025) · International Journal of Cancer · doi:10.1002/ijc.70197 · Cited by 18

Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia

Onishi‐Seebacher, M., Erikson, G. A., Sawitzki, Z., Ryan, D., Greve, G., Lübbert, M., & Jenuwein, T. (2021) · BMC Medical Genomics · doi:10.1186/s12920-021-01003-z · Cited by 19

Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia

Brabson, J. P., Leesang, T. E., Yap, Y. S., Wang, J., Lam, M. Q., Fang, B., Dolgalev, I., Barbieri, D. A., Strippoli, V., Bañuelos, C. P., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112027 · Cited by 18

Powerful and accurate detection of temporal gene expression patterns from multi-sample multi-stage single-cell transcriptomics data with TDEseq

Fan, Y., Li, L., & Sun, S. (2024) · Genome biology · doi:10.1186/s13059-024-03237-3 · Cited by 24

Intravenous Vitamin C Administration Improved Blood Cell Counts and Health-Related Quality of Life of Patient with History of Relapsed Acute Myeloid Leukaemia

Foster, M. N., Carr, A. C., Antony, A., Peng, S., & Fitzpatrick, M. (2018) · Antioxidants · doi:10.3390/antiox7070092 · Cited by 18

Endogenous Retrovirus RNA Expression Differences between Race, Stage and HPV Status Offer Improved Prognostication among Women with Cervical Cancer

Alldredge, J. K., Kumar, V., Nguyen, J., Sanders, B. E., Gomez, K. E., Jayachandran, K., Zhang, J., Schwarz, J. K., & Rahmatpanah, F. B. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021492 · Cited by 17

Vitamin C and D supplementation in acute myeloid leukemia

Mouchel, P., Bérard, E., Tavitian, S., Gadaud, N., Vergez, F., Rieu, J., Luquet, I., Sarry, A., Huguet, F., Largeaud, L., et al. (2023) · Blood Advances · doi:10.1182/bloodadvances.2023010559 · Cited by 17

Antioxidant Roles/Functions of Ascorbic Acid (Vitamin C)

Agwu, E., Ezihe, C. O., & Kaigama, G. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.110589 · Cited by 23

Commonly Integrated Epigenetic Modifications of Differentially Expressed Genes Lead to Adaptive Resistance in Cancer

Emran, A. A., Marzese, D. M., Menon, D. R., Hammerlindl, H., Ahmed, F., Richtig, E., Duijf, P. H. G., Hoon, D. S. �., & Schaider, H. (2019) · Epigenomics · doi:10.2217/epi-2018-0173 · Cited by 19

The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia

Travaglini, S., Gurnari, C., Antonelli, S., Silvestrini, G., Noguera, N. I., Ottone, T., & Voso, M. T. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.930205 · Cited by 18

Epigenetic priming improves salvage chemotherapy in diffuse large B-cell lymphoma via endogenous retrovirus-induced cGAS-STING activation

Liu, J., Min, S., Kim, D., Park, J., Park, E., Koh, Y., Shin, D.-Y., Kim, T. K., Byun, J. M., Yoon, S., et al. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01493-x · Cited by 17

Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma

Hoang, N.-M., Liu, Y., Bates, P. D., Heaton, A. R., Lopez, A. F., Liu, P., Zhu, F., Chen, R., Kondapelli, A., Zhang, X., et al. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101484 · Cited by 20

Out of sight, out of mind? Germ cells and the potential impacts of epigenomic drugs

Jarred, E. G., Bildsoe, H., & Western, P. S. (2018) · F1000Research · doi:10.12688/f1000research.15935.1 · Cited by 17

Ten‐Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy

Liang, J., Na, X., Meng, L., He, L., Shu, T., Fang, Y., Zhang, B., Zhao, Z., Guo, C., Li, J., et al. (2025) · MedComm · doi:10.1002/mco2.70245 · Cited by 15

Viral mimicry in cancer therapy

Rosenberg, L., & Vabret, N. (2025) · Trends in cancer · doi:10.1016/j.trecan.2025.08.010 · Cited by 19

Regulation and Functional Significance of 5-Hydroxymethylcytosine in Cancer

Arvinden, V. R., Rao, A. K. D. M., Rajkumar, T., & Mani, S. (2017) · Epigenomes · doi:10.3390/epigenomes1030019 · Cited by 15

Double-stranded RNA induction asa potential dynamic biomarkerfor DNA-demethylating agents

Kang, M., Kharbash, R., Byun, J. M., Jeon, J., Ali, A. A., Ku, D., Yoon, J., Ku, Y., Sohn, J., Lee, S., et al. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.07.014 · Cited by 14

Mitoepigenetics and gliomas: epigenetic alterations to mitochondrial DNA and nuclear DNA alter mtDNA expression and contribute to glioma pathogenicity

Grady, C. I., Walsh, L. M., & Heiss, J. D. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1154753 · Cited by 14

Prognostic value of downregulated 5-hydroxymethylcytosine expression in renal cell carcinoma: a 10 year follow-up retrospective study

Chen, S., Zhou, Q., Liu, T., Zhang, W., Zeng, X., & Guo, Z. (2019) · Journal of Cancer · doi:10.7150/jca.38283 · Cited by 14

The dual role of vitamin C in cancer: from antioxidant prevention to prooxidant therapeutic applications

Cao, X., Yi, Y., Ji, M., Liu, Y., Wang, D., & Zhu, H. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1633447 · Cited by 13

Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia

Humphries, S., Bond, D. R., Germon, Z. P., Keely, S., Enjeti, A. K., Dun, M. D., & Lee, H. J. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01566-x · Cited by 15

Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia

Long, B., Shan, Y., Sun, Y., Wang, T., Li, X., Huang, K., Zhang, W., He, Y. J., Wen, R., Li, Y., et al. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166357 · Cited by 13

A study on DNA methylation modifying natural compounds identified EGCG for induction of IFI16 gene expression related to the innate immune response in cancer cells

Khan, M. I., Nur, S. M., & Abdulaal, W. H. (2022) · Oncology Letters · doi:10.3892/ol.2022.13339 · Cited by 13

Efficient activation of hundreds of LTR12C elements reveals cis-regulatory function determined by distinct epigenetic mechanisms

Ohtani, H., Liu, M., Liang, G., Jang, H. J., & Jones, P. A. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae498 · Cited by 13

A perspective on diet, epigenetics and complex diseases: where is the field headed next?

Coppedè, F., Franzago, M., Giardina, E., Nigro, C. L., Matullo, G., Moltrasio, C., Nacmias, B., Pileggi, S., Sirchia, S. M., Stoccoro, A., et al. (2022) · Epigenomics · doi:10.2217/epi-2022-0239 · Cited by 12

Vitamin C Against Cancer

Mastrangelo, D., Massai, L., Fioritoni, G., & Lo‐Coco, F. (2017) · InTech eBooks · doi:10.5772/intechopen.68746 · Cited by 13

Epigenetic drugs: More than meets the eye

Esteller, M. (2017) · Epigenetics · doi:10.1080/15592294.2017.1322881 · Cited by 11

Epigenetically programmed resistance to chemo- and immuno-therapies

Walker, R. R., Rentia, Z., & Chiappinelli, K. B. (2023) · Advances in cancer research · doi:10.1016/bs.acr.2022.12.001 · Cited by 13

Retinoic acid-inducible gene-I like receptor pathway in cancer: modification and treatment

Du, G., Xing, Z., Zhou, J., Cui, C., Liu, C., Liu, Y., & Li, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1227041 · Cited by 10

Inflammatory mitochondrial signalling and viral mimicry in cancer

Nesci, S., Marchi, S., Hu, J. K., Marincola, F. M., & Algieri, C. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06931-3 · Cited by 14

Pharmacological GLUT3 salvage augments the efficacy of vitamin C-induced TET2 restoration in acute myeloid leukemia

Liu, J., Min, S., Kim, D. C., Park, J., Park, E., Pei, S., Koh, Y., Shin, D., Byun, J. M., Ko, M., et al. (2023) · Leukemia · doi:10.1038/s41375-023-01954-5 · Cited by 12

Clinical and molecular characteristics associated with Vitamin C deficiency in myeloid malignancies; real world data from a prospective cohort

Premnath, N., Chung, S. S., Weinberg, O. K., Ikpefan, R., Pandey, M., Kaur, G., Geethakumari, P. R., Afrough, A., Awan, F. T., Anderson, L. D., et al. (2022) · Leukemia Research · doi:10.1016/j.leukres.2022.107001 · Cited by 9

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism

Gutierrez, W. R., Scherer, A., Rytlewski, J. D., Laverty, E. A., Sheehan, A. P., McGivney, G. R., Brockman, Q. R., Knepper-Adrian, V., Roughton, G. A., Quelle, D. E., et al. (2022) · JCI Insight · doi:10.1172/jci.insight.159419 · Cited by 9

The Membrane Electrical Potential and Intracellular pH as Factors Influencing Intracellular Ascorbate Concentration and Their Role in Cancer Treatment

Gąbka, M., Dałek, P., Przybyło, M., Gackowski, D., Oliński, R., & Langner, M. (2021) · Cells · doi:10.3390/cells10112964 · Cited by 9

Transposable elements activation triggers necroptosis in mouse embryonic stem cells

Jin, L., He, J., Feng, H., Li, S., Liu, H., Dong, H., Hu, M., Huang, J., Wu, H., Chen, J., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05705-3 · Cited by 11

New promising developments for potential therapeutic applications of high-dose ascorbate as an anticancer drug

Testa, U., Pelosi, E., & Castelli, G. (2020) · Hematology/Oncology and Stem Cell Therapy · doi:10.1016/j.hemonc.2020.11.002 · Cited by 8

Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation

Cheng, K. C. L., Frost, J. M., Sanchez-Luque, F. J., García-Cañadas, M., Taylor, D., Yang, W. R., Irayanar, B., Sampath, S., Patani, H., Agger, K., et al. (2023) · Epigenetics & Chromatin · doi:10.1186/s13072-023-00514-6 · Cited by 8

Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies

Zhao, X. O., Zong, J., Liu, Y., Aili, T., Qiu, M., Wu, J., & Hu, B. (2024) · Aging and Disease · doi:10.14336/ad.2024.0123-1 · Cited by 7

Cancer Metabolism

Reid, M. A., Sanderson, S. M., & Locasale, J. W. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-47674-4.00009-8 · Cited by 9

Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3

Puccini, A., Loupakis, F., Stintzing, S., Cao, S., Battaglin, F., Tokunaga, R., Naseem, M., Berger, M. D., Soni, S., Zhang, W., et al. (2019) · European Journal of Cancer · doi:10.1016/j.ejca.2019.01.105 · Cited by 6

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

Yang, X., Chen, Q., Yu, Y., Zang, Y., Zheng, R., Zhang, Z., Lu, S., & Zhou, L. (2026) · MedComm – Oncology · doi:10.1002/mog2.70065 · Cited by 7

Unperturbed dormancy recording reveals stochastic awakening strategies in endocrine treated breast cancer cellsPreprint

Rosano, D., Sofyalı, E., Dhiman, H., Ivanoiu, D., Slaven, N., Hong, S. P., Rocca, A., Bravaccini, S., Ravaioli, S., Noberini, R., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.21.440779 · Cited by 8

The mechanisms and drug therapies of colorectal cancer and epigenetics: bibliometrics and visualized analysis

Tian, S. I. P., & Chen, M. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1466156 · Cited by 5

Ação antioxidante e propriedades funcionais do morango no organismo humano

Nunes, G., & Novello, D. (2021) · Revista Valore · doi:10.22408/reva502020246e-5004 · Cited by 5

Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays

Tiedemann, R. L., Eden, H. E., Huang, Z., Robertson, K. D., & Rothbart, S. B. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1294-1_7 · Cited by 5

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal

Bond, D. R., Burnard, S. M., Uddipto, K., Hunt, K. V., Harvey, B. M., Reinhardt, L. S., Lawlor-O’Neill, C., Roper, E. A., Humphries, S., Murray, H. C., et al. (2025) · Leukemia · doi:10.1038/s41375-025-02693-5 · Cited by 4

Metabolic adaptations underlie epigenetic vulnerabilities in chemoresistant breast cancerPreprint

Deblois, G., Tonekaboni, S. A. M., Kao, Y. I., Tai, F., Liu, X., Ettayebi, I., Guilhamon, P., Fedor, A. N., Grillo, G., Murison, A. J., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/286054 · Cited by 4

Viral mimicry acts as a tumor suppressor in colitis

Larsen, F., Jeong, W., Schep, D., Good, H. J., Shin, A. E., Zhang, L., Derouet, M., Wang, T. C., Castellani, C. A., Shooshtari, P., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-68850-1 · Cited by 4

The physiological functions of ascorbate in the development of cancer

Agathocleous, M. (2025) · Disease Models & Mechanisms · doi:10.1242/dmm.052201 · Cited by 4

Ultra-sensitive and specific detection of ascorbic acid using a laser-engraved graphene electrode modified with a molecularly imprinted polymer

Jin, W., Yao, H., Wang, X., Li, M., Gao, X., Chen, W., & Zhang, Y. (2025) · Journal of Materials Chemistry C · doi:10.1039/d4tc04412f · Cited by 3

Vitamins and dietary supplements in cancer treatment: is there a need for increased usage?

Esposito, T., Pentimalli, F., Giordano, A., & Cortellino, S. (2025) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2025.2501077 · Cited by 4

Enhancement of the Antileukemic Action of the Inhibitors of DNA and Histone Methylation: 5-Aza-2′-Deoxycytidine and 3-Deazaneplanocin-A by Vitamin C

Momparler, R. L., Côté, S., & Momparler, L. F. (2021) · Epigenomes · doi:10.3390/epigenomes5020007 · Cited by 4

DNA Methylation Changes in Cancer

Thomson, J. P., & Meehan, R. R. (2017) · Cancer drug discovery and develogment/Cancer drug discovery and development · doi:10.1007/978-3-319-59786-7_4 · Cited by 3

High Doses of Vitamin C and Leukemia: In Vitro Update

Mastrangelo, D., Massai, L., Fioritoni, G., Lo‐Coco, F., Noguera, N. I., & Testa, U. (2018) · InTech eBooks · doi:10.5772/intechopen.71484 · Cited by 3

PRC2 Loss and DNMT Inhibition Boost Viral Mimicry in Cancer

Guil, S., & Esteller, M. (2022) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-0733 · Cited by 3

Evolvability and emergence of tumor heterogeneity as a space–time function

Saha, B., Vannucci, L. E., Saha, B., Tenti, P., & Baral, R. (2022) · Cytokine · doi:10.1016/j.cyto.2022.156061 · Cited by 3

KnowYourCG: Facilitating base-level sparse methylome interpretation

Goldberg, D. C., Fu, H., Atkins, D., Moyer, E. J., Lee, C. N., Deng, Y., & Zhou, W. (2025) · Science Advances · doi:10.1126/sciadv.adw3027 · Cited by 4

Medical applications of stabilized ascorbic acid: a review of recent advances

Kim, Y., & Choi, G. (2023) · Medical Lasers · doi:10.25289/ml.23.032 · Cited by 2

L-Ascorbic Acid in the Epigenetic Regulation of Cancer Development and Stem Cell Reprogramming

Kovina, A. P., Petrova, N. V., Razin, S. V., & Kantidze, O. L. (2020) · Acta Naturae · doi:10.32607/actanaturae.11060 · Cited by 2

DNA-Demethylating Agents Enhance Cytolytic Activity of CD8 T Cells and Anti-Tumor ImmunityPreprint

Yau, H. L., Chakravarthy, A., de Almeida, F. C., Allard, D., Singhania, R., Ettayebi, I., Shen, S. Y., Medina, T. D. S., Mehdipour, P., Morancho, B., et al. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3155506 · Cited by 2

Faculty Opinions recommendation of Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells.

Bellastella, A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734936741.793557350 · Cited by 2

Lessons Learned from Cancer Metabolism for Physiology and DiseasePreprint

Campbell, S. L., & Christofk, H. R. (2024) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041554 · Cited by 2

The interplay between H3K36 methylation and DNA methylation in cancer

Dan, J., Du, Z., Zhang, J., & Chen, T. (2023) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2023.0234 · Cited by 1

The Vitamin C Level in Cases with Hematological Malignancies

Sincan, G., Erdem, F., & Kızıltunç, A. (2024) · Harran Üniversitesi Tıp Fakültesi Dergisi · doi:10.35440/hutfd.1458028 · Cited by 1

Oral vitamin C supplementation in patients with clonal cytopenia of undetermined significance or lower‐risk myeloid malignancies: Results from EVITA, a phase 2 randomized, placebo‐controlled trial

Mikkelsen, S. U., Al-Mousawi, A., Puglisi, A. B., Vallentin, A. P., Mortensen, A. Ø., Madaj, Z., Hinoue, T., Ottesen, H. N., Jespersen, J. S., Gillberg, L., et al. (2026) · Cancer · doi:10.1002/cncr.70549 · Cited by 2

Targeting Epigenetic Modifiers for Cancer Treatments

Chee, C. S., & Leung, D. (2018) · Current Pharmacology Reports · doi:10.1007/s40495-018-0130-9 · Cited by 1

Vitamin C: Current Concepts in Human Physiology

Carr, A. C., & Natarajan, R. (2018) · MDPI eBooks · doi:10.3390/books978-3-03897-295-2 · Cited by 1

Use of vitamins and minerals as dietary supplements for better health and cancer prevention

Arfin, S., & Kumar, D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-19193-0.00003-4 · Cited by 1

The epigenomic impact of methylation in metabolic dysfunction and cancer

Zahnow, C. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816843-1.00005-9 · Cited by 1

Profile of Peter A. Jones

Viegas, J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617318113

A Clinically Distinct and ‘Atypical’ Subgroup of Head and Neck Cancers Positive for a CpG Island Methylator Phenotype

Weisenberger, D. J. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.008

Obtenção de prolipossomas por recobrimento de sacarose micronizada, produção de lipossomas multilamelares encapsulando curcumina e incorporação das vesículas em iogurte

Silva, G. D. S. (2019) · doi:10.11606/t.74.2019.tde-13022019-102116

Inhibiting DDX3X Triggers Tumor-Intrinsic Type I Interferon Response and Enhances Anti-Tumor ImmunityPreprint

Choi, H., Kwon, J., Sun, J., Cho, M. S., Sun, Y., Casey, J. L., Toretsky, J. A., & Han, C. (2020) · doi:10.21203/rs.3.rs-60342/v1

Epigenetics in diagnosis, prognosis and therapy

Qazi, S., & Sharma, A. K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819753-0.00019-2

Novel approach in various types of cancer treatments

Patil, S. A., Shinde, K. S., Choudhary, H. B., Patekar, R. R., & Rede, S. D. (2021) · World Journal of Advanced Research and Reviews · doi:10.30574/wjarr.2021.10.3.0291

Extreme Activation of Androgen Receptor for Prostate Cancer Therapy

Alizadeh‐Ghodsi, M. (2021) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)

Multi-omic time-series analysis of T-cells as a model for identification of biomarkers, treatments and upstream disease regulators

Rundquist, O. (2021) · Linköping studies in science and technology. Dissertations · doi:10.3384/9789179291044

Faculty Opinions recommendation of Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

Schellhorn, H. E. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.729069935.793537498

Ascorbic Acid Therapy in Hematological Malignancies - The Current Knowledge and Future DirectionsPreprint

Lam, W. K., Ha, C. Y., & Yip, S. F. (2022) · doi:10.32388/pmlz1t.2

Ascorbic Acid Therapy in Hematological Malignancies - The Current Knowledge and Future DirectionsPreprint

Lam, W. K., Ha, C. Y., & Yip, S. F. (2022) · doi:10.32388/pmlz1t

Ascorbic Acid Therapy in Hematological Malignancies - The Current Knowledge and Future DirectionsPreprint

Lam, W. K., Ha, C. Y., & Yip, S. F. (2022) · doi:10.32388/pmlz1t.3

Ascorbic Acid Therapy in Hematological Malignancies - The Current Knowledge and Future DirectionsPreprint

Lam, W. K., Ha, C. Y., & Yip, S. F. (2022) · doi:10.32388/pmlz1t.4

Ascorbic Acid Therapy in Hematological Malignancies - The Current Knowledge and Future DirectionsPreprint

Lam, W. K., Ha, C. Y., & Yip, S. F. (2022) · doi:10.32388/pmlz1t.5

Data from G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma

Kelly, G., Al‐Ejeh, F., McCuaig, R., Casciello, F., Kamal, N. A., Ferguson, B., Pritchard, A. L., Ali, S., Silva, I. P., Wilmott, J. S., et al. (2023) · doi:10.1158/1078-0432.c.6531297

Data from G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma

Kelly, G., Al‐Ejeh, F., McCuaig, R., Casciello, F., Kamal, N. A., Ferguson, B., Pritchard, A. L., Ali, S., Silva, I. P., Wilmott, J. S., et al. (2023) · doi:10.1158/1078-0432.c.6531297.v1

Data from Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response

Choi, H., Kwon, J., Cho, M. S., Sun, Y., Zheng, X., Wang, J., Bouker, K. B., Casey, J. L., Atkins, M. B., Toretsky, J. A., et al. (2023) · doi:10.1158/0008-5472.c.6513106.v1

Methylation and hydroxymethylation in cancer

Asmar, F., Gillberg, L., & Grønbæk, K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91367-6.00020-9

Stress-induced endogenous-dsRNAs drive beta-cells to IFN-I statePreprint

Chi, K. K., Senapati, P., Leung, A., & Schones, D. E. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.10.566600

DNA methylation in T cell leukaemia

Bensberg, M. (2024) · Linköping University medical dissertations · doi:10.3384/9789180755405

Abstract IA14: Targeting human endogenous retroviruses for epigenetic therapy

Jones, P. A. (2017) · Cancer Research · doi:10.1158/1538-7445.newfront17-ia14

Oral Vitamin C Supplementation to Azacitidine in Patients with Myeloid Cancer: Normalization of Plasma Vitamin C Induces Epigenetic Changes

Gillberg, L., Ørskov, A. D., Nasif, A., Otani, H., Madaj, Z., Hansen, J. W., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, J., et al. (2018) · Blood · doi:10.1182/blood-2018-99-111525

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

Gillberg, L., Ørskov, A. D., Nasif, A., Ohtani, H., Madaj, Z., Hansen, J. W., Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., et al. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0739-5 · Cited by 91

The role of vitamin C in epigenetic cancer therapy

Mikkelsen, S. U., Gillberg, L., Lykkesfeldt, J., & Grønbæk, K. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.03.017 · Cited by 62

Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7

Sajadian, S. O., Tripura, C., Samani, F. S., Ruoß, M., Dooley, S., Baharvand, H., & Nussler, A. K. (2016) · Clinical Epigenetics · doi:10.1186/s13148-016-0213-6 · Cited by 63