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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

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Targeting cancer vulnerabilities with high-dose vitamin C

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Ascorbic Acid in Cancer Treatment: Let the Phoenix Fly

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Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy

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Vitamin C in stem cell reprogramming and cancer

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High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model

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Intravenous Vitamin C for Cancer Therapy – Identifying the Current Gaps in Our Knowledge

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Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retrovirusesPreprint

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Dual inhibition of DNA and histone methyltransferases increases viral mimicry in ovarian cancer cells

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Reprogramming the epigenome with vitamin C

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Transposable element regulation and expression in cancer

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HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors

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Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells

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An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

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Vitamin C as a Modulator of the Response to Cancer Therapy

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TET family dioxygenases and the TET activator vitamin C in immune responses and cancer

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Epigenetic Regulation of Genomic Stability by Vitamin C

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Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

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Vitamin C – A new player in regulation of the cancer epigenome

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The Cancer Epigenome: Exploiting Its Vulnerabilities for Immunotherapy

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Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia

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Mechanisms of anti-cancer effects of ascorbate: Cytotoxic activity and epigenetic modulation

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Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

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Role of Transposable Elements in Genome Stability: Implications for Health and Disease

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Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis

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Genetic and Epigenetic Alterations in Bladder Cancer

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Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer

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Novel Strategies for Cancer Treatment: Highlights from the 55th IACR Annual Conference

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DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma

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DNA methyltransferases in hematological malignancies

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Differentiation therapy of myeloid leukemia: four decades of development

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TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia

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Endogenous Retrovirus-Derived Long Noncoding RNA Enhances Innate Immune Responses via Derepressing RELA Expression

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Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine

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Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor Guadecitabine (SGI‐110) in Hepatocellular Carcinoma

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Vitamin C Transporters and Their Implications in Carcinogenesis

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The role of vitamin C in epigenetic cancer therapy

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Reactivation of Endogenous Retroelements in Cancer Development and Therapy

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Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response

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Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?

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Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia

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The Epigenetic Role of Vitamin C in Neurodevelopment

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Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response

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Vitamin C supramolecular hydrogel for enhanced cancer immunotherapy

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The role of DNA-demethylating agents in cancer therapy

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On the physiological and cellular homeostasis of ascorbate

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Health-promoting role of dietary bioactive compounds through epigenetic modulations: a novel prophylactic and therapeutic approach

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Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells

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The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry

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Mitochondrial and Metabolic Pathways Regulate Nuclear Gene Expression to Control Differentiation, Stem Cell Function, and Immune Response in Leukemia

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Pharmacologic Induction of BRCAness in BRCA-Proficient Cancers: Expanding PARP Inhibitor Use

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High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients

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Vitamin C: From nutrition to oxygen sensing and epigenetics

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Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs

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HERVs and Cancer—A Comprehensive Review of the Relationship of Human Endogenous Retroviruses and Human Cancers

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Interplay between activation of endogenous retroviruses and inflammation as common pathogenic mechanism in neurological and psychiatric disorders

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Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer

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Nano-vitamin C: A promising candidate for therapeutic applications

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Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells

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G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma

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