The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
PIF3 is a negative regulator of the CBF pathway and freezing tolerance in Arabidopsis
Open accessAbstract
Significance: PHYTOCHROME-INTERACTING FACTORS (PIFs) are central integrators of plants’ responses to various environmental signals. In this study, we show that PIF3 acts as a negative regulator of plant cold acclimation by directly repressing the expression of CBF genes, whereas its protein stability is negatively regulated by two F-box proteins, EBF1 and EBF2, via the 26S proteasome pathway. Moreover, EBF1 and EBF2 are degraded under cold stress, which enhances the stability of PIF3 protein. Collectively, our study establishes an important regulatory paradigm for PIF3 in preventing runaway expression of the CBF genes at low temperature, which allows plants to adapt to and withstand harsh environments.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms
Thomashow, M. F. (1999) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.50.1.571 · Cited by 3,551
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (1998) · The Plant Cell · doi:10.1105/tpc.10.8.1391 · Cited by 3,044
Cold stress regulation of gene expression in plants
Chinnusamy, V., Zhu, J., & Zhu, J.-K. (2007) · Trends in Plant Science · doi:10.1016/j.tplants.2007.07.002 · Cited by 2,002
Arabidopsis CBF1 Overexpression Induces COR Genes and Enhances Freezing Tolerance
Jaglo-Ottosen, K. R., Gilmour, S. J., Zarka, D. G., Schabenberger, O., & Thomashow, M. F. (1998) · Science · doi:10.1126/science.280.5360.104 · Cited by 1,702
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis
Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.-H., Hong, X., Agarwal, M., & Zhu, J.-K. (2003) · Genes & Development · doi:10.1101/gad.1077503 · Cited by 1,673
Gilmour, S. J., Zarka, D. G., Stockinger, E. J., Salazar, M. P., Houghton, J. M., & Thomashow, M. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00310.x · Cited by 1,163
Agarwal, M., Hao, Y., Kapoor, A., Dong, C.-H., Fujii, H., Zheng, X., & Zhu, J.-K. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605895200 · Cited by 949
Phytochromes function as thermosensors in Arabidopsis
Jung, J.-H., Domijan, M., Klose, C., Biswas, S., Ezer, D., Gao, M., Khattak, A. K., Box, M. S., Charoensawan, V., Cortijo, S., et al. (2016) · Science · doi:10.1126/science.aaf6005 · Cited by 935
Guo, H., & Ecker, J. R. (2003) · Cell · doi:10.1016/s0092-8674(03)00969-3 · Cited by 928
Self-citationPhytochrome B integrates light and temperature signals in Arabidopsis
Legris, M., Klose, C., Burgie, E. S., Rojas, C. C. R., Neme, M., Hiltbrunner, A., Wigge, P. A., Schäfer, E., Vierstra, R. D., & Casal, J. J. (2016) · Science · doi:10.1126/science.aaf5656 · Cited by 867
Cited by
Molecular Regulation of Plant Responses to Environmental Temperatures
Ding, Y., Shi, Y., & Yang, S. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.02.004 · Cited by 787
Self-citationRegulatory networks in plant responses to drought and cold stress
Kim, J.-S., Kidokoro, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (2024) · Plant Physiology · doi:10.1093/plphys/kiae105 · Cited by 303
Guo, Q., Li, X., Niu, L., Jameson, P. E., & Zhou, W. (2021) · Plant Physiology · doi:10.1093/plphys/kiab050 · Cited by 253
Xie (2021) · doi:10.1111/jipb.13161 · Cited by 180
Metadata
- Authors
- Jiang, B., Shi, Y., Zhang, X., Xin, X., Qi, L., Guo, H., Li, J., & Yang, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2017-07-24
- Volume
- 114
- Issue
- 32
- Pages
- E6695-E6702
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2738282840
- Cited by
- 284
- References
- 44
- FWCI
- 20.47
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: PIF3 is a negative regulator of the CBF pathway and freezing tolerance in Arabidopsis. https://app.cochat.ai/papers/10.1073/pnas.1706226114
- The paper
- Jiang, B., Shi, Y., Zhang, X., Xin, X., Qi, L., Guo, H., Li, J., & Yang, S. (2017). PIF3 is a negative regulator of the CBF pathway and freezing tolerance in Arabidopsis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1706226114
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
