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MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity
Open accessAbstract
Significance: Middle East respiratory syndrome (MERS) is a zoonotic disease of global health concern, and dromedary camels are the source of human infection. Although Africa has the largest number of dromedary camels, and MERS-coronavirus (MERS-CoV) is endemic in these camels, locally acquired zoonotic MERS is not reported from Africa. However, little is known of the genetic or phenotypic characterization of MERS-CoV from Africa. In this study we characterize MERS-CoV from Burkina Faso, Nigeria, Morocco, and Ethiopia. We demonstrate viral genetic and phenotypic differences in viruses from West Africa, which may be relevant to differences in zoonotic potential, highlighting the need for studies of MERS-CoV at the animal–human interface.
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Guindon, S., Dufayard, J.-F., Lefort, V., Anisimova, M., Hordijk, W., & Gascuel, O. (2010) · Systematic Biology · doi:10.1093/sysbio/syq010 · Cited by 18,376
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Metadata
- Authors
- Chu, D. K. W., Hui, K. P. Y., Perera, R. A. P. M., Miguel, E., Niemeyer, D., Zhao, J., Channappanavar, R., Dudas, G., Oladipo, J. O., Traoré, A., Fassi-Fihri, O., Ali, A., Demissié, G. F., Muth, D., Chan, M. C. W., Nicholls, J. M., Meyerholz, D. K., Kuranga, S. A., Mamo, G., Zhou, Z., So, R. T. Y., Hemida, M. G., Webby, R. J., Roger, F., Rambaut, A., Poon, L. L. M., Perlman, S., Drosten, C., Chevalier, V., & Peiris, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2018-03-05
- Volume
- 115
- Issue
- 12
- Pages
- 3144-3149
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2789368753
- Cited by
- 191
- References
- 1
- FWCI
- 20.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Chu, D. K. W., Hui, K. P. Y., Perera, R. A. P. M., Miguel, E., Niemeyer, D., Zhao, J., Channappanavar, R., Dudas, G., Oladipo, J. O., Traoré, A., Fassi-Fihri, O., Ali, A., Demissié, G. F., Muth, D., Chan, M. C. W., Nicholls, J. M., Meyerholz, D. K., Kuranga, S. A., Mamo, G., . . . Peiris, M. (2018). MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1718769115
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
