The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Neuroectodermal differentiation from mouse multipotent adult progenitor cells
Open accessAbstract
We recently showed that a rare cell from murine bone marrow, which we termed multipotent adult progenitor cells (MAPCs), can be expanded for >120 population doublings. Mouse (m)MAPCs differentiate into mesenchymal lineage cells as well as endothelium and endoderm, and, when injected in the blastocyst, mMAPCs contribute to most if not all somatic cell lineages including the different cell types of the brain. Our results, reported herein, demonstrate that mMAPCs can also be induced to differentiate into cells having anatomical and electrophysiological characteristics similar to those of midbrain neurons. Differentiation to a neuronal phenotype was achieved by coculturing mMAPCs with astrocytes, suggesting that neuronal differentiation may require astrocyte-derived factors similar to what is required for the differentiation of embryonic stem cells and neural stem cells to neurons. Differentiation of mMAPCs to neuron-like cells follows similar developmental steps as described for embryonic stem cells and neural stem cells. MAPCs therefore may constitute a source of cells for treatment of central nervous system disorders.
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Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Changing potency by spontaneous fusion
Ying, Q.-L., Nichols, J., Evans, E. P., & Smith, A. G. (2002) · Nature · doi:10.1038/nature729 · Cited by 1,494
Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor
Cattaneo, E., & McKay, R. (1990) · Nature · doi:10.1038/347762a0 · Cited by 717
Cited by
Stem cell therapy for human neurodegenerative disorders–how to make it work
Lindvall, O., Kokaia, Z., & Martinez-Serrano, A. (2004) · Nature Medicine · doi:10.1038/nm1064 · Cited by 915
In vitro Hepatic Differentiation of Human Mesenchymal Stem Cells
Lee, K., Kuo, T. K., Whang–Peng, J., Chung, Y., Lin, C., Chou, S., Chen, J., Chen, Y., & Lee, O. K. (2004) · Hepatology · doi:10.1002/hep.20469 · Cited by 865
Lu, P., Blesch, A., & Tuszynski, M. H. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20148 · Cited by 435
Herder, V., Hansmann, F., Stangel, M., Skripuletz, T., Baumgärtner, W., & Beineke, A. (2011) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2011.01168.x · Cited by 45
Metadata
- Authors
- Jiang, Y., Henderson, D., Blackstad, M., Chen, A., Miller, R. F., & Verfaillie, C. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-09-30
- Volume
- 100
- Issue
- suppl_1
- Pages
- 11854-11860
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1991646393
- Cited by
- 349
- References
- 3
- FWCI
- 13.19
- Type
- journal article
- Language
- en
- Open access
- green
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- Jiang, Y., Henderson, D., Blackstad, M., Chen, A., Miller, R. F., & Verfaillie, C. M. (2003). Neuroectodermal differentiation from mouse multipotent adult progenitor cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1834196100
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